8A2X

Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP(S)-2'F,2'dAMP(S))

Summary for 8A2X

• Entry DOI: 10.2210/pdb8a2x/pdb
• Descriptor: Stimulator of interferon protein, 9-[(1~{R},3~{R},6~{R},8~{R},9~{R},10~{R},12~{R},15~{R},17~{R},18~{S})-8-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanylidene)-3,12-bis(sulfanyl)-2,4,7,11,13-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-17-yl]purin-6-amine (2 entities in total)
• Functional Keywords: sting, antiviral, activator, antiviral protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 23881.62

Authors

Klima, M.,Smola, M.,Boura, E. (deposition date: 2022-06-06, release date: 2023-12-20)

• Primary citation: Klima, M.,Smola, M.,Boura, E.; Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP(S)-2'F,2'dAMP(S)); To Be Published,

Experimental method

X-RAY DIFFRACTION (3 Å)