5C9K

Crystal structure of a highly fibrillogenic Arg24Gly mutant of the Recombinant variable domain 6AJL2

Summary for 5C9K

• Entry DOI: 10.2210/pdb5c9k/pdb
• Related: 3B5G 3BDX
• Descriptor: Amyloid lambda 6 light chain variable region PIP, ACETATE ION (3 entities in total)
• Functional Keywords: lambda vi subgroup, beta-sandwich, immunoglobulin, al amyloidosis, immune system
• Biological source: Homo sapiens
• Total number of polymer chains: 8
• Total formula weight: 95130.32

Authors

Hernandez-Santoyo, A.,Rodriguez-Romero, A.,Luna-Martinez, O.D.,Becerril-Lujan, B. (deposition date: 2015-06-27, release date: 2015-08-05, Last modification date: 2023-09-27)

• Primary citation: Luna-Martinez, O.D.,Villalba-Velazquez, M.I.,Sanchez-Alcala, R.,Hernandez-Santoyo, A.,Fernandez-Velasco, D.A.,Rodriguez-Romero, A.,Becerril-Lujan, B.; Mutating amyloidogenic lambda6 light chain AR back to germline 6aJL2; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.92 Å)