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6QIP
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BU of 6qip by Molmil
Ternary complex of FcRn ectodomain, FcRn binding optimised human serum albumin and the albumin-biniding side chain of the human growth hormone derivative somapacitan
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-MERCAPTOETHANOL, Beta-2-microglobulin, ...
Authors:Johansson, E.
Deposit date:2019-01-21
Release date:2020-02-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Identification of Binding Sites on Human Serum Albumin for Somapacitan, a Long-Acting Growth Hormone Derivative.
Biochemistry, 59, 2020
6QIO
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BU of 6qio by Molmil
Ternary complex of FcRn ectodomain, FcRn binding optimised human serum albumin and the human growth hormone derivative somapacitan
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, CYSTEINE, ...
Authors:Johansson, E.
Deposit date:2019-01-21
Release date:2020-02-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Identification of Binding Sites on Human Serum Albumin for Somapacitan, a Long-Acting Growth Hormone Derivative.
Biochemistry, 59, 2020
1N76
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BU of 1n76 by Molmil
CRYSTAL STRUCTURE OF HUMAN SEMINAL LACTOFERRIN AT 3.4 A RESOLUTION
Descriptor: CARBONATE ION, FE (III) ION, LACTOFERRIN, ...
Authors:Kumar, J, Weber, W, Munchau, S, Yadav, S, Singh, S.B, Sarvanan, K, Paramsivam, M, Sharma, S, Kaur, P, Bhushan, A, Srinivasan, A, Betzel, C, Singh, T.P.
Deposit date:2002-11-12
Release date:2003-02-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structure of human seminal lactoferrin at 3.4A resolution
Indian J.Biochem.Biophys., 40, 2003
7LLI
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BU of 7lli by Molmil
Stimulatory immune receptor protein complex
Descriptor: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ...
Authors:Rice, M.T, Littler, D.R, Rossjohn, J, Gully, B.S.
Deposit date:2021-02-04
Release date:2021-11-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Recognition of the antigen-presenting molecule MR1 by a V delta 3 + gamma delta T cell receptor.
Proc.Natl.Acad.Sci.USA, 118, 2021
7LLJ
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BU of 7llj by Molmil
Inhibitory immune receptor protein complex
Descriptor: Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, N-(6-formyl-4-oxo-3,4-dihydropteridin-2-yl)acetamide, ...
Authors:Rice, M.T, Littler, D.R, Rossjohn, J, Gully, B.S.
Deposit date:2021-02-04
Release date:2021-11-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Recognition of the antigen-presenting molecule MR1 by a V delta 3 + gamma delta T cell receptor.
Proc.Natl.Acad.Sci.USA, 118, 2021
1I6Q
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Formation of a protein intermediate and its trapping by the simultaneous crystallization process: Crystal structure of an iron-saturated intermediate in the FE3+ binding pathway of camel lactoferrin at 2.7 resolution
Descriptor: CARBONATE ION, FE (III) ION, LACTOFERRIN
Authors:Khan, J.A, Kumar, P, Srinivasan, A, Singh, T.P.
Deposit date:2001-03-03
Release date:2001-11-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Protein intermediate trapped by the simultaneous crystallization process. Crystal structure of an iron-saturated intermediate in the Fe3+ binding pathway of camel lactoferrin at 2.7 a resolution.
J.Biol.Chem., 276, 2001
6D78
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BU of 6d78 by Molmil
The complex between high-affinity TCR DMF5(alpha-D26Y,beta-L98W) and human Class I MHC HLA-A2 with the bound MART-1(27-35)peptide
Descriptor: Beta-2-microglobulin, DMF5 alpha chain,DMF5 alpha chain, DMF5 beta chain,DMF5 beta chain, ...
Authors:Hellman, L.M, Singh, N.K.
Deposit date:2018-04-24
Release date:2019-04-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.347 Å)
Cite:Improving T Cell Receptor On-Target Specificity via Structure-Guided Design.
Mol. Ther., 27, 2019
6DKP
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BU of 6dkp by Molmil
The complex among DMF5(alpha-D26Y, alpha-Y50A,beta-L98W) TCR, human Class I MHC HLA-A2 and MART-1(26-35)(A27L) peptide
Descriptor: Beta-2-microglobulin, DMF5 T-cell Receptor Alpha Chain fusion, DMF5 T-cell Receptor Beta Chain fusion, ...
Authors:Hellman, L.M, Singh, N.K.
Deposit date:2018-05-30
Release date:2019-04-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.966 Å)
Cite:Improving T Cell Receptor On-Target Specificity via Structure-Guided Design.
Mol. Ther., 27, 2019
6D64
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BU of 6d64 by Molmil
Crystal Structure of Human CD1b in Complex with POPC
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1,2-ETHANEDIOL, Beta-2-microglobulin, ...
Authors:Shahine, A.E, Rossjohn, J.
Deposit date:2018-04-20
Release date:2019-01-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids.
Nat Commun, 10, 2019
4F7P
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BU of 4f7p by Molmil
Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009H1N1 PB1 (496-505)
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
Authors:Liu, J, Zhang, S, Tan, S, Yi, Y, Wu, B, Zhu, F, Wang, H, Qi, J, Gao, G.F.
Deposit date:2012-05-16
Release date:2012-10-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals.
J.Virol., 86, 2012
4F7M
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BU of 4f7m by Molmil
Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009 H1N1 PA (649-658)
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
Authors:Liu, J, Zhang, S, Tan, S, Yi, Y, Wu, B, Zhu, F, Wang, H, Qi, J, George, F.G.
Deposit date:2012-05-16
Release date:2012-10-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals.
J.Virol., 86, 2012
1SQY
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BU of 1sqy by Molmil
Structure of human diferric lactoferrin at 2.5A resolution using crystals grown at pH 6.5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
Authors:Vikram, P, Prem Kumar, R, Singh, N, Kumar, J, Ethayathulla, A.S, Sharma, S, Kaur, P, Singh, T.P.
Deposit date:2004-03-22
Release date:2004-04-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of human diferric lactoferrin at 2.5A resolution using crystals grown at pH 6.5.
To be Published
4O2E
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BU of 4o2e by Molmil
A peptide complexed with HLA-B*3901
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-39 alpha chain, ...
Authors:Sun, M, Liu, J, Qi, J, Tefsen, B, Shi, Y, Yan, J, Gao, G.F.
Deposit date:2013-12-17
Release date:2014-07-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.981 Å)
Cite:N alpha-terminal acetylation for T cell recognition: molecular basis of MHC class I-restricted n alpha-acetylpeptide presentation
J.Immunol., 192, 2014
4O2F
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BU of 4o2f by Molmil
A peptide complexed with HLA-B*3901
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-39 alpha chain, ...
Authors:Sun, M, Liu, J, Qi, J, Tefsen, B, Shi, Y, Yan, J, Gao, G.F.
Deposit date:2013-12-17
Release date:2014-07-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:N alpha-terminal acetylation for T cell recognition: molecular basis of MHC class I-restricted n alpha-acetylpeptide presentation
J.Immunol., 192, 2014
1JW1
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BU of 1jw1 by Molmil
Crystallization and structure determination of goat lactoferrin at 4.0 resolution: A new form of packing in lactoferrins with a high solvent content in crystals
Descriptor: FE (III) ION, LACTOFERRIN
Authors:Kumar, P, Yadav, S, Singh, T.P.
Deposit date:2001-09-02
Release date:2003-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystallization and structure determonation of goat lactoferrin at 4.0A resolution: A new form of packing in lactoferrins with a high solvent content in crystals
INDIAN J.BIOCHEM.BIOPHYS., 39, 2002
1LCF
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BU of 1lcf by Molmil
CRYSTAL STRUCTURE OF COPPER-AND OXALATE-SUBSTITUTED HUMAN LACTOFERRIN AT 2.0 ANGSTROMS RESOLUTION
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, COPPER (II) ION, ...
Authors:Smith, C.A, Anderson, B.F, Baker, H.M, Baker, E.N.
Deposit date:1994-01-11
Release date:1994-08-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of copper- and oxalate-substituted human lactoferrin at 2.0 A resolution.
Acta Crystallogr.,Sect.D, 50, 1994
1L5T
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BU of 1l5t by Molmil
Crystal Structure of a Domain-Opened Mutant (R121D) of the Human Lactoferrin N-lobe Refined From a Merohedrally-Twinned Crystal Form.
Descriptor: lactoferrin
Authors:Jameson, G.B, Anderson, B.F, Breyer, W.A, Tweedie, J.W, Baker, E.N.
Deposit date:2002-03-07
Release date:2002-03-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of a domain-opened mutant (R121D) of the human lactoferrin N-lobe refined from a merohedrally twinned crystal form.
Acta Crystallogr.,Sect.D, 58, 2002
1LCT
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BU of 1lct by Molmil
STRUCTURE OF THE RECOMBINANT N-TERMINAL LOBE OF HUMAN LACTOFERRIN AT 2.0 ANGSTROMS RESOLUTION
Descriptor: CARBONATE ION, FE (III) ION, LACTOFERRIN
Authors:Day, C.L, Anderson, B.F, Baker, E.N.
Deposit date:1993-06-19
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the recombinant N-terminal lobe of human lactoferrin at 2.0 A resolution.
J.Mol.Biol., 232, 1993
6JTO
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BU of 6jto by Molmil
Crystal structure of HLA-C05 in complex with a tumor mut10m peptide
Descriptor: 10-mer peptide, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Bai, P, Zhou, Q, Wei, P, Lei, Y.
Deposit date:2019-04-11
Release date:2020-04-15
Last modified:2021-05-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Rational discovery of a cancer neoepitope harboring the KRAS G12D driver mutation.
Sci China Life Sci, 2021
6LA7
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BU of 6la7 by Molmil
Cryo-EM structure of echovirus 11 complexed with its uncoating receptor FcRn at pH 5.5
Descriptor: Beta-2-microglobulin, Capsid protein VP1, Capsid protein VP2, ...
Authors:Liu, S, Gao, F.G.
Deposit date:2019-11-12
Release date:2020-10-07
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Molecular and structural basis of Echovirus 11 infection by using the dual-receptor system of CD55 and FcRn.
Chin.Sci.Bull., 2020
7KKZ
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BU of 7kkz by Molmil
Crystal structure of mouse anti-HIV potent neutralizing antibody M4H2K1
Descriptor: 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Heavy chain of Fab fragment of mouse monoclonal antibody M4H2K1, ...
Authors:Kumar, S, Wilson, I.A.
Deposit date:2020-10-28
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles.
Mbio, 12, 2021
7KMD
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BU of 7kmd by Molmil
Crystal structure of a HIV-1 clade C isolate Du172.17 HR1.R4.664 Env trimer in complex with human Fabs PGT124 and 35O22
Descriptor: 124 Heavy chain, 124 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kumar, S, Wilson, I.A.
Deposit date:2020-11-02
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.39228582 Å)
Cite:Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles.
Mbio, 12, 2021
7KLC
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BU of 7klc by Molmil
Crystal structure of M4H2K1 Fab bound to HIV-1 BG505 gp120 core and to 17b Fab
Descriptor: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kumar, S, Wilson, I.A.
Deposit date:2020-10-29
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles.
Mbio, 12, 2021
5VGE
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BU of 5vge by Molmil
Crystal structure of HLA-C*07:02 in complex with RYR peptide
Descriptor: ARG-TYR-ARG-PRO-GLY-THR-VAL-ALA-LEU, Beta-2-microglobulin, ZINC ION, ...
Authors:Mobbs, J.I, Vivian, J.P, Gras, S, Rossjohn, J.
Deposit date:2017-04-11
Release date:2017-06-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and regulatory diversity shape HLA-C protein expression levels.
Nat Commun, 8, 2017
5D7I
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BU of 5d7i by Molmil
Structure of human MR1-Ac-6-FP in complex with human MAIT M33.64 TCR
Descriptor: Beta-2-microglobulin, GLYCEROL, M33.64 TCR Alpha Chain, ...
Authors:Keller, A.N, Woolley, R.E, Rossjohn, J.
Deposit date:2015-08-14
Release date:2016-01-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition.
Immunity, 44, 2016

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