6QIP
Ternary complex of FcRn ectodomain, FcRn binding optimised human serum albumin and the albumin-biniding side chain of the human growth hormone derivative somapacitan
Summary for 6QIP
Entry DOI | 10.2210/pdb6qip/pdb |
Descriptor | Serum albumin, IgG receptor FcRn large subunit p51, Beta-2-microglobulin, ... (8 entities in total) |
Functional Keywords | complex, albumin binding, long-acting growth hormone, somapacitan, hormone, transport protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 111045.20 |
Authors | Johansson, E. (deposition date: 2019-01-21, release date: 2020-02-05, Last modification date: 2024-01-24) |
Primary citation | Johansson, E.,Nielsen, A.D.,Demuth, H.,Wiberg, C.,Schjodt, C.B.,Huang, T.,Chen, J.,Jensen, S.,Petersen, J.,Thygesen, P. Identification of Binding Sites on Human Serum Albumin for Somapacitan, a Long-Acting Growth Hormone Derivative. Biochemistry, 59:1410-1419, 2020 Cited by PubMed: 32208682DOI: 10.1021/acs.biochem.0c00019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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