PDB: 73665 resultsInfo pagesStatus searchChemie searchBIRD

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5ONS	Crystal structure of the minimal DENR-MCTS1 complex Descriptor: Density-regulated protein, GLYCEROL, Malignant T-cell-amplified sequence 1, ... Authors: Ahmed, Y.L, Sinning, I. Deposit date: 2017-08-04 Release date: 2018-05-23 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.14 Å) Cite: DENR-MCTS1 heterodimerization and tRNA recruitment are required for translation reinitiation. PLoS Biol., 16, 2018
3OIJ	Crystal structure of Saccharomyces Cerevisiae Nep1/Emg1 bound to S-adenosylhomocysteine and 2 molecules of cognate RNA Descriptor: 5'-R(*GP*GP*GP*CP*UP*UP*CP*AP*AP*CP*GP*CP*CP*C)-3', Essential for mitotic growth 1, MAGNESIUM ION, ... Authors: Thomas, S.R, LaRonde-LeBlanc, N. Deposit date: 2010-08-19 Release date: 2010-12-01 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis. Nucleic Acids Res., 39, 2011
3J0O	Core of mammalian 80S pre-ribosome in complex with tRNAs fitted to a 9A cryo-EM map: classic PRE state 2 Descriptor: 40S ribosomal RNA fragment, 60S ribosomal RNA fragment, Ribosomal protein L10a, ... Authors: Budkevich, T, Giesebrecht, J, Altman, R, Munro, J, Mielke, T, Nierhaus, K, Blanchard, S, Spahn, C.M. Deposit date: 2011-10-05 Release date: 2011-11-16 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (9 Å) Cite: Structure and dynamics of the Mammalian ribosomal pretranslocation complex. Mol.Cell, 44, 2011
3J0P	Core of mammalian 80S pre-ribosome in complex with tRNAs fitted to a 10.6A cryo-em map: rotated PRE state 1 Descriptor: 40S ribosomal RNA fragment, 60S ribosomal RNA fragment, Ribosomal protein L10a, ... Authors: Budkevich, T, Giesebrecht, J, Altman, R, Munro, J, Mielke, T, Nierhaus, K, Blanchard, S, Spahn, C.M. Deposit date: 2011-10-06 Release date: 2011-11-16 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (10.6 Å) Cite: Structure and dynamics of the Mammalian ribosomal pretranslocation complex. Mol.Cell, 44, 2011
3P87	Structure of human PCNA bound to RNASEH2B PIP box peptide Descriptor: Proliferating cell nuclear antigen, Ribonuclease H2 subunit B Authors: Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P. Deposit date: 2010-10-13 Release date: 2011-02-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.99 Å) Cite: PCNA directs type 2 RNase H activity on DNA replication and repair substrates. Nucleic Acids Res., 39, 2011
2P40	Crystal Structure of Dengue Methyltransferase in Complex with 7MeGpppG Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, SULFATE ION, type II methyltransferase Authors: Egloff, M.P, Marseilles Structural Genomics Program @ AFMB (MSGP) Deposit date: 2007-03-11 Release date: 2007-08-28 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.701 Å) Cite: Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5 J.Mol.Biol., 372, 2007
5L7P	In silico-powered specific incorporation of photocaged Dopa at multiple protein sites Descriptor: (2~{S})-2-azanyl-3-[3-[(2-nitrophenyl)methoxy]-4-oxidanyl-phenyl]propanoic acid, CALCIUM ION, CHLORIDE ION, ... Authors: Hauf, M, Richter, F, Schneider, T, Martins, B.M, Baumann, T, Durkin, P, Dobbek, H, Moeglich, A, Budisa, N. Deposit date: 2016-06-03 Release date: 2017-09-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Photoactivatable Mussel-Based Underwater Adhesive Proteins by an Expanded Genetic Code. Chembiochem, 18, 2017
4AIM	Crystal structure of C. crescentus PNPase bound to RNase E recognition peptide Descriptor: PHOSPHATE ION, POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE, RIBONUCLEASE, ... Authors: Hardwick, S.W, Gubbey, T, Hug, I, Jenal, U, Luisi, B.F. Deposit date: 2012-02-10 Release date: 2012-04-18 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Crystal Structure of Caulobacter Crescentus Polynucleotide Phosphorylase Reveals a Mechanism of RNA Substrate Channelling and RNA Degradosome Assembly. Open Biol., 2, 2012
4AID	Crystal structure of C. crescentus PNPase bound to RNase E recognition peptide Descriptor: PHOSPHATE ION, POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE, RIBONUCLEASE, ... Authors: Hardwick, S.W, Gubbey, T, Hug, I, Jenal, U, Luisi, B.F. Deposit date: 2012-02-09 Release date: 2012-04-18 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal Structure of Caulobacter Crescentus Polynucleotide Phosphorylase Reveals a Mechanism of RNA Substrate Channelling and RNA Degradosome Assembly. Open Biol., 2, 2012
3V9W	Crystal structure of RNase T in complex with a preferred ssDNA (TTA) with two Mg in the active site Descriptor: COBALT (II) ION, DNA (5'-D(*GP*CP*TP*TP*A)-3'), MAGNESIUM ION, ... Authors: Hsiao, Y.-Y, Yuan, H.S. Deposit date: 2011-12-28 Release date: 2012-07-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.702 Å) Cite: How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes Nucleic Acids Res., 40, 2012
3CV7	Crystal structure of porcine aldehyde reductase ternary complex Descriptor: 3,5-dichloro-2-hydroxybenzoic acid, Alcohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Carbone, V, El-Kabbani, O. Deposit date: 2008-04-18 Release date: 2008-10-28 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.412 Å) Cite: Structure of aldehyde reductase in ternary complex with coenzyme and the potent 20alpha-hydroxysteroid dehydrogenase inhibitor 3,5-dichlorosalicylic acid: Implications for inhibitor binding and selectivity Arch.Biochem.Biophys., 479, 2008
4M57	Crystal structure of the pentatricopeptide repeat protein PPR10 from maize Descriptor: Chloroplast pentatricopeptide repeat protein 10 Authors: Yin, P, Li, Q, Yan, C, Liu, Y, Yan, N. Deposit date: 2013-08-08 Release date: 2013-10-30 Last modified: 2013-12-18 Method: X-RAY DIFFRACTION (2.86 Å) Cite: Structural basis for the modular recognition of single-stranded RNA by PPR proteins. Nature, 504, 2013
3V9U	Crystal structure of RNase T in complex with a preferred ssDNA (AAT) with two Mg in the active site Descriptor: COBALT (II) ION, DNA (5'-D(*TP*TP*AP*CP*AP*AP*T)-3'), MAGNESIUM ION, ... Authors: Hsiao, Y.-Y, Yuan, H.S. Deposit date: 2011-12-28 Release date: 2012-07-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.298 Å) Cite: How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes Nucleic Acids Res., 40, 2012
3VA3	Crystal structure of RNase T in complex with a duplex DNA product (stem loop DNA with 2 nucleotide 3' overhang) Descriptor: COBALT (II) ION, DNA (5'-D(*GP*GP*CP*CP*CP*TP*CP*TP*TP*TP*AP*GP*GP*GP*CP*CP*TP*T)-3'), Ribonuclease T Authors: Hsiao, Y.-Y, Yuan, H.S. Deposit date: 2011-12-28 Release date: 2012-07-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.714 Å) Cite: How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes Nucleic Acids Res., 40, 2012
3DAT	Crystal structure of the ternary MTX NADPH complex of Bacillus anthracis dihydrofolate reductase Descriptor: Dihydrofolate reductase, METHOTREXATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Bennett, B.C, Dealwis, C.G. Deposit date: 2008-05-30 Release date: 2009-04-14 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.3 Å) Cite: X-ray structure of the ternary MTX.NADPH complex of the anthrax dihydrofolate reductase: a pharmacophore for dual-site inhibitor design. J.Struct.Biol., 166, 2009
3V9X	Crystal structure of RNase T in complex with a preferred ssDNA (AAA) with two Mg in the active site Descriptor: DNA (5'-D(*TP*TP*AP*TP*AP*AP*A)-3'), MAGNESIUM ION, Ribonuclease T Authors: Hsiao, Y.-Y, Yuan, H.S. Deposit date: 2011-12-28 Release date: 2012-07-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes Nucleic Acids Res., 40, 2012
3VA0	Crystal structure of RNase T in complex with a di-nucleotide product (GG) with one Mg in the active site Descriptor: COBALT (II) ION, DNA (5'-D(*GP*G)-3'), MAGNESIUM ION, ... Authors: Hsiao, Y.-Y, Yuan, H.S. Deposit date: 2011-12-28 Release date: 2012-07-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.201 Å) Cite: How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes Nucleic Acids Res., 40, 2012
3DAU	Crystal structure of the ternary MTX NADPH complex of Escherichia coli dihydrofolate reductase Descriptor: Dihydrofolate reductase, METHOTREXATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Bennett, B.C, Dealwis, C.G. Deposit date: 2008-05-30 Release date: 2009-04-14 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.5 Å) Cite: X-ray structure of the ternary MTX.NADPH complex of the anthrax dihydrofolate reductase: a pharmacophore for dual-site inhibitor design. J.Struct.Biol., 166, 2009
1XBP	Inhibition of peptide bond formation by pleuromutilins: The structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with Tiamulin Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... Authors: Schluenzen, F, Pyetan, E, Fucini, P, Yonath, A, Harms, J.M. Deposit date: 2004-08-31 Release date: 2005-03-01 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin. Mol.Microbiol., 54, 2004
6EXN	Post-catalytic P complex spliceosome with 3' splice site docked Descriptor: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat: UBC4 RNA, ... Authors: Wilkinson, M.E, Fica, S.M, Galej, W.P, Norman, C.M, Newman, A.J, Nagai, K. Deposit date: 2017-11-08 Release date: 2018-01-17 Last modified: 2020-10-07 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection. Science, 358, 2017
2CQH	Solution structure of the RNA binding domain of IGF-II mRNA-binding protein 2 Descriptor: IGF-II mRNA-binding protein 2 isoform a Authors: Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-05-20 Release date: 2005-11-20 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the RNA binding domain of IGF-II mRNA-binding protein 2 To be Published
7N0B	Cryo-EM structure of SARS-CoV-2 nsp10-nsp14 (WT)-RNA complex Descriptor: CALCIUM ION, Non-structural protein 10, Proofreading exoribonuclease, ... Authors: Liu, C, Yang, Y. Deposit date: 2021-05-25 Release date: 2021-07-28 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural basis of mismatch recognition by a SARS-CoV-2 proofreading enzyme. Science, 373, 2021
7N0D	Cryo-EM structure of the tetrameric form of SARS-CoV-2 nsp10-nsp14 (E191A)-RNA complex Descriptor: CHAPSO, MAGNESIUM ION, Non-structural protein 10, ... Authors: Liu, C, Yang, Y. Deposit date: 2021-05-25 Release date: 2021-07-28 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Structural basis of mismatch recognition by a SARS-CoV-2 proofreading enzyme. Science, 373, 2021
7N0C	Cryo-EM structure of the monomeric form of SARS-CoV-2 nsp10-nsp14 (E191A)-RNA complex Descriptor: MAGNESIUM ION, Non-structural protein 10, Proofreading exoribonuclease, ... Authors: Liu, C, Yang, Y. Deposit date: 2021-05-25 Release date: 2021-07-28 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis of mismatch recognition by a SARS-CoV-2 proofreading enzyme. Science, 373, 2021
7BMK	ATP-Competitive Partial Antagonists-'PAIR's-Rheostatically Modulate IRE1alpha's Kinase Helix-alphaC to Segregate its RNase-Mediated Biological Outputs Descriptor: 1,2-ETHANEDIOL, 2,2,2-tris(fluoranyl)-~{N}-[4-[3-[2-[[(3~{S})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxynaphthalen-1-yl]ethanesulfonamide, DI(HYDROXYETHYL)ETHER, ... Authors: Feldman, H.C, Ghosh, R, Auyeung, V, Mueller, J.L, Vidadala, V.N, Olivier, A, Backes, B.J, Zikherman, J, Papa, F.R, Maly, D.J. Deposit date: 2021-01-20 Release date: 2021-09-29 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.85 Å) Cite: ATP-competitive partial antagonists of the IRE1 alpha RNase segregate outputs of the UPR. Nat.Chem.Biol., 17, 2021

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