3OIJ

Crystal structure of Saccharomyces Cerevisiae Nep1/Emg1 bound to S-adenosylhomocysteine and 2 molecules of cognate RNA

Summary for 3OIJ

• Entry DOI: 10.2210/pdb3oij/pdb
• Related: 3O7B 3OII 3OIN
• Descriptor: Essential for mitotic growth 1, 5'-R(*GP*GP*GP*CP*UP*UP*CP*AP*AP*CP*GP*CP*CP*C)-3', S-ADENOSYL-L-HOMOCYSTEINE, ... (5 entities in total)
• Functional Keywords: emg1, scnep1, spout, ribosome biogenesis, methyltransferase, rrna processing, ribosomal protein
• Biological source: Saccharomyces cerevisiae; More
• Cellular location: Nucleus, nucleolus : Q06287
• Total number of polymer chains: 4
• Total formula weight: 65655.55

Authors

Thomas, S.R.,LaRonde-LeBlanc, N. (deposition date: 2010-08-19, release date: 2010-12-01, Last modification date: 2023-09-06)

• Primary citation: Thomas, S.R.,Keller, C.A.,Szyk, A.,Cannon, J.R.,Laronde-Leblanc, N.A.; Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.; Nucleic Acids Res., 39:2445-2457, 2011; PubMed: 21087996; DOI: 10.1093/nar/gkq1131

Experimental method

X-RAY DIFFRACTION (3 Å)