4WGJ
 
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4WQT
 | | Thermus thermophilus RNA polymerase complexed with an RNA cleavage stimulating factor (a GreA/Gfh1 chimeric protein) | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Murayama, Y, Sekine, S, Yokoyama, S. | | Deposit date: | 2014-10-22 | | Release date: | 2015-02-18 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (4.4 Å) | | Cite: | The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions.
Mol.Cell, 57, 2015
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6WQE
 | | Solution Structure of the IWP-051-bound H-NOX from Shewanella woodyi in the Fe(II)CO ligation state | | Descriptor: | 5-fluoro-2-{1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)-1H-pyrazol-3-yl}pyrimidin-4-ol, CARBON MONOXIDE, Heme NO binding domain protein, ... | | Authors: | Chen, C.Y, Lee, W, Montfort, W.R. | | Deposit date: | 2020-04-28 | | Release date: | 2020-07-22 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the Shewanella woodyi H-NOX protein in the presence and absence of soluble guanylyl cyclase stimulator IWP-051.
Protein Sci., 30, 2021
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3TW4
 | | Crystal Structure of Human Septin 7 GTPase Domain | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Septin-7 | | Authors: | Serrao, V.H.B, Alessandro, F, Pereira, H.M, Thiemann, O.T, Garratt, R.C. | | Deposit date: | 2011-09-21 | | Release date: | 2011-11-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Promiscuous interactions of human septins: The GTP binding domain of SEPT7 forms filaments within the crystal.
Febs Lett., 585, 2011
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4WL0
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2ZQZ
 | | R-state structure of allosteric L-lactate dehydrogenase from Lactobacillus casei | | Descriptor: | L-lactate dehydrogenase, SULFATE ION | | Authors: | Arai, K, Ishimitsu, T, Fushinobu, S, Uchikoba, H, Matsuzawa, H, Taguchi, H. | | Deposit date: | 2008-08-22 | | Release date: | 2009-09-08 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Active and inactive state structures of unliganded Lactobacillus casei allosteric L-lactate dehydrogenase.
Proteins, 78, 2010
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4WOD
 | | The duplicated taurocyamine kinase from Schistosoma mansoni complexed with arginine | | Descriptor: | ARGININE, Taurocyamine kinase | | Authors: | Merceron, R, Awama, A, Montserret, R, Marcillat, O, Gouet, P. | | Deposit date: | 2014-10-15 | | Release date: | 2015-04-15 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The Substrate-free and -bound Crystal Structures of the Duplicated Taurocyamine Kinase from the Human Parasite Schistosoma mansoni.
J.Biol.Chem., 290, 2015
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4WY5
 | | Structural analysis of two fungal esterases from Rhizomucor miehei explaining their substrate specificity | | Descriptor: | Esterase, SULFATE ION | | Authors: | Qin, Z, Yang, S, Duan, X, Yan, Q, Jiang, Z. | | Deposit date: | 2014-11-15 | | Release date: | 2015-07-01 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.43 Å) | | Cite: | Structural insights into the substrate specificity of two esterases from the thermophilic Rhizomucor miehei
J.Lipid Res., 56, 2015
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4X09
 | | Structure of human RNase 6 in complex with sulphate anions | | Descriptor: | GLYCEROL, Ribonuclease K6, SULFATE ION | | Authors: | Prats-Ejarque, G, Arranz-Trullen, J, Blanco, J.A, Pulido, D, Moussaoui, M, Boix, E. | | Deposit date: | 2014-11-21 | | Release date: | 2016-04-06 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.722 Å) | | Cite: | The first crystal structure of human RNase 6 reveals a novel substrate-binding and cleavage site arrangement.
Biochem.J., 473, 2016
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8SV8
 | | Cryo-EM structure of a double loaded human UBA7-UBE2L6-ISG15 thioester mimetic complex from a composite map | | Descriptor: | ADENOSINE MONOPHOSPHATE, Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-like protein ISG15, ... | | Authors: | Afsar, M, Jia, L, Ruben, E.A, Olsen, S.K. | | Deposit date: | 2023-05-15 | | Release date: | 2023-10-11 | | Method: | ELECTRON MICROSCOPY (3.38 Å) | | Cite: | Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer.
Nat Commun, 14, 2023
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1U7V
 | | Crystal Structure of the phosphorylated Smad2/Smad4 heterotrimeric complex | | Descriptor: | Mothers against decapentaplegic homolog 2, Mothers against decapentaplegic homolog 4 | | Authors: | Chacko, B.M, Qin, B.Y, Tiwari, A, Shi, G, Lam, S, Hayward, L.J, de Caestecker, M, Lin, K. | | Deposit date: | 2004-08-04 | | Release date: | 2004-09-28 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis of heteromeric smad protein assembly in tgf-Beta signaling
Mol.Cell, 15, 2004
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4NC4
 | | Crystal structure of photoreceptor AtUVR8 mutant W285F and light-induced structural changes at 120K | | Descriptor: | MAGNESIUM ION, Ultraviolet-B receptor UVR8 | | Authors: | Yang, X, Zeng, X, Zhao, K.-H, Ren, Z. | | Deposit date: | 2013-10-23 | | Release date: | 2016-10-26 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Dynamic Crystallography Reveals Early Signalling Events in Ultraviolet Photoreceptor UVR8.
Nat Plants, 1, 2015
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3TZC
 | | Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG)(Y155F) from Vibrio cholerae | | Descriptor: | 3-oxoacyl-[acyl-carrier protein] reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION | | Authors: | Hou, J, Chruszcz, M, Zheng, H, Grabowski, M, Domagalski, M, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2011-09-27 | | Release date: | 2011-10-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.
J.Bacteriol., 198, 2015
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4WP9
 | | Crystal structure of Adenylyl cyclase MA1120 from Mycobacterium Avium bound to 2'5'-DD-3'-ATP, Calcium and Magnesium ion | | Descriptor: | 2',5'-dideoxyadenosine 3'-(tetrahydrogen triphosphate), CALCIUM ION, MAGNESIUM ION, ... | | Authors: | Bharambe, N.G, Barathy, D.V, Suguna, K. | | Deposit date: | 2014-10-17 | | Release date: | 2015-09-02 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.382 Å) | | Cite: | Autoinhibitory mechanism and activity-related structural changes in a mycobacterial adenylyl cyclase
J.Struct.Biol., 190, 2015
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4X1W
 | | Crystal structure of unbound RHDVb P domain | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, VP1 | | Authors: | Leuthold, M.M, Hansman, G.S. | | Deposit date: | 2014-11-25 | | Release date: | 2015-01-14 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural analysis of a rabbit hemorrhagic disease virus binding to histo-blood group antigens.
J.Virol., 89, 2015
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4WP8
 | | Crystal structure of Adenylyl cyclase Ma1120 from Mycobacterium Avium in complex with 2'5'-DD-3'-ATP and Manganese ion | | Descriptor: | 2',5'-dideoxyadenosine 3'-(tetrahydrogen triphosphate), CHLORIDE ION, MANGANESE (II) ION, ... | | Authors: | Barathy, D.V, Bharambe, N.G, Suguna, K. | | Deposit date: | 2014-10-17 | | Release date: | 2015-09-02 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Autoinhibitory mechanism and activity-related structural changes in a mycobacterial adenylyl cyclase
J.Struct.Biol., 190, 2015
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4WQM
 | | Structure of the toluene 4-monooxygenase NADH oxidoreductase T4moF, K270S K271S variant | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Acheson, J.F, Fox, B.G. | | Deposit date: | 2014-10-22 | | Release date: | 2015-09-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Structure of T4moF, the Toluene 4-Monooxygenase Ferredoxin Oxidoreductase.
Biochemistry, 54, 2015
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4WJ9
 | | Structure of Human apo ALDH1A1 | | Descriptor: | CHLORIDE ION, Retinal dehydrogenase 1, YTTERBIUM (III) ION | | Authors: | Morgan, C.A, Hurley, T.D. | | Deposit date: | 2014-09-29 | | Release date: | 2014-12-10 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1.
Chem.Biol.Interact., 234, 2015
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4WO1
 | | Crystal structure of the DAP12 transmembrane domain in lipid cubic phase | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, TYRO protein tyrosine kinase-binding protein | | Authors: | Call, M.J, Call, M.E, Knoblich, K. | | Deposit date: | 2014-10-15 | | Release date: | 2015-06-03 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Transmembrane Complexes of DAP12 Crystallized in Lipid Membranes Provide Insights into Control of Oligomerization in Immunoreceptor Assembly.
Cell Rep, 11, 2015
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2ZTA
 | | X-RAY STRUCTURE OF THE GCN4 LEUCINE ZIPPER, A TWO-STRANDED, PARALLEL COILED COIL | | Descriptor: | GCN4 LEUCINE ZIPPER | | Authors: | O'Shea, E.K, Klemm, J.D, Kim, P.S, Alber, T. | | Deposit date: | 1991-07-05 | | Release date: | 1992-10-15 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil.
Science, 254, 1991
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4WQ5
 | | YgjD(V85E)-YeaZ heterodimer in complex with ATP | | Descriptor: | ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, FE (III) ION, ... | | Authors: | Zhang, W. | | Deposit date: | 2014-10-21 | | Release date: | 2015-01-28 | | Last modified: | 2015-02-25 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | The ATP-mediated formation of the YgjD-YeaZ-YjeE complex is required for the biosynthesis of tRNA t6A in Escherichia coli.
Nucleic Acids Res., 43, 2015
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4WP3
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4WOL
 | | Crystal Structure of the DAP12 transmembrane domain in lipidic cubic phase | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, POTASSIUM ION, TYRO protein tyrosine kinase-binding protein | | Authors: | Call, M.J, Call, M.E, Knoblich, K. | | Deposit date: | 2014-10-16 | | Release date: | 2015-06-03 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Transmembrane Complexes of DAP12 Crystallized in Lipid Membranes Provide Insights into Control of Oligomerization in Immunoreceptor Assembly.
Cell Rep, 11, 2015
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4X1Z
 | | Crystal structure of RHDVb P domain in complex with H type 2 | | Descriptor: | SODIUM ION, VP1, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose | | Authors: | Leuthold, M.M, Hansman, G.S. | | Deposit date: | 2014-11-25 | | Release date: | 2015-01-14 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.36 Å) | | Cite: | Structural analysis of a rabbit hemorrhagic disease virus binding to histo-blood group antigens.
J.Virol., 89, 2015
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4MHD
 | | Crystal structure of spermidine N-acetyltransferase from Vibrio cholerae in complex with spermidine | | Descriptor: | SPERMIDINE, Spermidine n1-acetyltransferase | | Authors: | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Kuhn, M.L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2013-08-29 | | Release date: | 2013-09-25 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | A Novel Polyamine Allosteric Site of SpeG from Vibrio cholerae Is Revealed by Its Dodecameric Structure.
J.Mol.Biol., 427, 2015
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