4WP9

Crystal structure of Adenylyl cyclase MA1120 from Mycobacterium Avium bound to 2'5'-DD-3'-ATP, Calcium and Magnesium ion

Summary for 4WP9

• Entry DOI: 10.2210/pdb4wp9/pdb
• Related: 4WP3 4WP8 4WPA
• Descriptor: Ma1120, MAGNESIUM ION, 2',5'-dideoxyadenosine 3'-(tetrahydrogen triphosphate), ... (5 entities in total)
• Functional Keywords: 2'5'-dd-3'-atp, p-site inhibitor, adenylyl cyclase, lyase
• Biological source: Mycobacterium avium
• Total number of polymer chains: 2
• Total formula weight: 40318.20

Authors

Bharambe, N.G.,Barathy, D.V.,Suguna, K. (deposition date: 2014-10-17, release date: 2015-09-02, Last modification date: 2023-11-08)

• Primary citation: Barathy, D.V.,Bharambe, N.G.,Syed, W.,Zaveri, A.,Visweswariah, S.S.,Cola sigmaf o, M.,Misquith, S.,Suguna, K.; Autoinhibitory mechanism and activity-related structural changes in a mycobacterial adenylyl cyclase; J.Struct.Biol., 190:304-313, 2015; PubMed: 25916753; DOI: 10.1016/j.jsb.2015.04.013

Experimental method

X-RAY DIFFRACTION (1.382 Å)