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4WP9

Crystal structure of Adenylyl cyclase MA1120 from Mycobacterium Avium bound to 2'5'-DD-3'-ATP, Calcium and Magnesium ion

Functional Information from GO Data
ChainGOidnamespacecontents
A0009190biological_processcyclic nucleotide biosynthetic process
A0035556biological_processintracellular signal transduction
B0009190biological_processcyclic nucleotide biosynthetic process
B0035556biological_processintracellular signal transduction
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue MG A 301
ChainResidue
ALEU204
APHE207
AHOH405
AHOH433
AHOH475

site_idAC2
Number of Residues7
Detailsbinding site for residue MG A 302
ChainResidue
AHOH448
AHOH476
AHOH503
AASP61
AASP105
AZDA303
ACA304

site_idAC3
Number of Residues26
Detailsbinding site for residue ZDA A 303
ChainResidue
AASP61
AILE62
AGLU64
ASER65
ATHR66
AGLN103
AGLY104
AASP105
AARG143
AMG302
ACA304
AHOH416
AHOH471
AHOH508
AHOH528
AHOH532
AHOH580
AHOH598
BLYS101
BMET108
BASP157
BLEU158
BVAL163
BALA164
BALA167
BARG168

site_idAC4
Number of Residues5
Detailsbinding site for residue CA A 304
ChainResidue
AASP61
AILE62
AASP105
AMG302
AZDA303

site_idAC5
Number of Residues4
Detailsbinding site for residue CA A 305
ChainResidue
AARG168
AGLN172
ALEU204
ALYS205

site_idAC6
Number of Residues26
Detailsbinding site for residue ZDA B 301
ChainResidue
ALYS101
AGLN103
AMET108
AASP157
ALEU158
AVAL163
AALA164
ALYS205
BASP61
BILE62
BGLU64
BSER65
BTHR66
BGLN103
BASP105
BARG143
BMG302
BCA303
BHOH407
BHOH410
BHOH423
BHOH428
BHOH435
BHOH503
BHOH520
BHOH560

site_idAC7
Number of Residues4
Detailsbinding site for residue MG B 302
ChainResidue
BASP61
BARG143
BZDA301
BHOH410

site_idAC8
Number of Residues4
Detailsbinding site for residue CA B 303
ChainResidue
BASP61
BILE62
BASP105
BZDA301

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PDB entries from 2024-11-06

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