1U7V
Crystal Structure of the phosphorylated Smad2/Smad4 heterotrimeric complex
Summary for 1U7V
Entry DOI | 10.2210/pdb1u7v/pdb |
Related | 1U7F |
Descriptor | Mothers against decapentaplegic homolog 2, Mothers against decapentaplegic homolog 4 (2 entities in total) |
Functional Keywords | smad, tgf-beta, signal transduction, protein complex, phosphorylation, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q15796 Q13485 |
Total number of polymer chains | 3 |
Total formula weight | 70734.00 |
Authors | Chacko, B.M.,Qin, B.Y.,Tiwari, A.,Shi, G.,Lam, S.,Hayward, L.J.,de Caestecker, M.,Lin, K. (deposition date: 2004-08-04, release date: 2004-09-28, Last modification date: 2023-08-23) |
Primary citation | Chacko, B.M.,Qin, B.Y.,Tiwari, A.,Shi, G.,Lam, S.,Hayward, L.J.,De Caestecker, M.,Lin, K. Structural basis of heteromeric smad protein assembly in tgf-Beta signaling Mol.Cell, 15:813-823, 2004 Cited by PubMed: 15350224DOI: 10.1016/j.molcel.2004.07.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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