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1U7V

Crystal Structure of the phosphorylated Smad2/Smad4 heterotrimeric complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, C)
Mothers against decapentaplegic homolog 2polymer19822499.32UniProt (Q15796)
Pfam (PF03166)
Homo sapiens (human)SMAD 2, Mothers against DPP homolog 2, Mad-related protein 2, hMAD-2, JV18-1, hSMAD2
2C
(B)
Mothers against decapentaplegic homolog 4polymer23625735.31UniProt (Q13485)
Pfam (PF03166)
Homo sapiens (human)SMAD 4, Mothers against DPP homolog 4, Deletion target in pancreatic carcinoma 4, hSMAD4
Sequence modifications
A, C: 270 - 467 (UniProt: Q15796)
PDBExternal DatabaseDetails
Sep 465Ser 465modified residue
Sep 467Ser 467modified residue
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight70734.0
All*Total formula weight70734.0
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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