1U7V
Crystal Structure of the phosphorylated Smad2/Smad4 heterotrimeric complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Mothers against decapentaplegic homolog 2 | polymer | 198 | 22499.3 | 2 | UniProt (Q15796) Pfam (PF03166) | Homo sapiens (human) | SMAD 2, Mothers against DPP homolog 2, Mad-related protein 2, hMAD-2, JV18-1, hSMAD2 |
| 2 | C (B) | Mothers against decapentaplegic homolog 4 | polymer | 236 | 25735.3 | 1 | UniProt (Q13485) Pfam (PF03166) | Homo sapiens (human) | SMAD 4, Mothers against DPP homolog 4, Deletion target in pancreatic carcinoma 4, hSMAD4 |
Sequence modifications
A, C: 270 - 467 (UniProt: Q15796)
| PDB | External Database | Details |
|---|---|---|
| Sep 465 | Ser 465 | modified residue |
| Sep 467 | Ser 467 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 70734.0 | |
| All* | Total formula weight | 70734.0 |






