4WO1

Crystal structure of the DAP12 transmembrane domain in lipid cubic phase

Summary for 4WO1

Entry DOI	10.2210/pdb4wo1/pdb
Related	2L34 2L35 4WOL
Descriptor	TYRO protein tyrosine kinase-binding protein, CALCIUM ION, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... (4 entities in total)
Functional Keywords	alpha-helix transmembrane signaling, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	15503.49
Authors	Call, M.J.,Call, M.E.,Knoblich, K. (deposition date: 2014-10-15, release date: 2015-06-03, Last modification date: 2023-09-27)
Primary citation	Knoblich, K.,Park, S.,Lutfi, M.,van 't Hag, L.,Conn, C.E.,Seabrook, S.A.,Newman, J.,Czabotar, P.E.,Im, W.,Call, M.E.,Call, M.J. Transmembrane Complexes of DAP12 Crystallized in Lipid Membranes Provide Insights into Control of Oligomerization in Immunoreceptor Assembly. Cell Rep, 11:1184-1192, 2015 Cited by PubMed: 25981043 DOI: 10.1016/j.celrep.2015.04.045 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.14 Å)

Structure validation