4WO1
Crystal structure of the DAP12 transmembrane domain in lipid cubic phase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | TYRO protein tyrosine kinase-binding protein | polymer | 33 | 3331.0 | 4 | UniProt (O43914) | Homo sapiens (Human) | DNAX-activation protein 12,Killer-activating receptor-associated protein,KAR-associated protein |
| 2 | E (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 3 | F, G, H, I, J... (A, B, C, D) | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 6 | Chemie (OLC) | |||
| 4 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 8 - 40 (UniProt: O43914)
| PDB | External Database | Details |
|---|---|---|
| Val 21 | Met 48 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 13324.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2179.3 | |
| All* | Total formula weight | 15503.5 |
