4WO1

Crystal structure of the DAP12 transmembrane domain in lipid cubic phase

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue CA A 101

Chain	Residue
A	ASP23
A	HOH203
A	HOH204
A	HOH205
B	ASP23
B	HOH204
C	HOH204
C	HOH205
D	HOH205

---

site_id	AC2
Number of Residues	4
Details	binding site for residue OLC A 102

Chain	Residue
A	VAL34
C	VAL34
C	TYR35
D	OLC101

---

site_id	AC3
Number of Residues	8
Details	binding site for residue OLC B 101

Chain	Residue
A	GLY14
A	GLY18
A	GLY22
B	LEU29
B	PHE36
B	LEU40
B	HOH201
C	VAL21

---

site_id	AC4
Number of Residues	6
Details	binding site for residue OLC B 102

Chain	Residue
A	LEU29
A	PHE36
B	GLY14
B	GLY18
B	VAL21
B	GLY22

---

site_id	AC5
Number of Residues	8
Details	binding site for residue OLC C 101

Chain	Residue
B	ALA17
C	GLY18
C	GLY18
C	ILE19
C	GLY22
D	LEU29
D	LEU32
D	PHE36

---

site_id	AC6
Number of Residues	5
Details	binding site for residue OLC D 101

Chain	Residue
A	OLC102
B	VAL34
D	ALA31
D	VAL34
D	TYR35

---

site_id	AC7
Number of Residues	8
Details	binding site for residue OLC D 102

Chain	Residue
A	VAL20
C	LEU29
C	LEU37
D	VAL15
D	GLY18
D	ILE19
D	GLY22
D	LEU26

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	80
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"25981043","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25981043","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Site: {"description":"Important for interaction with transmembrane receptors","evidences":[{"source":"PubMed","id":"20890284","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---