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2N7K
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BU of 2n7k by Molmil
Unveiling the structural determinants of KIAA0323 binding preference for NEDD8
Descriptor: NEDD8, Protein KHNYN
Authors:Santonico, E, Nepravishta, R, Mattioni, A, Valentini, E, Mandaliti, W, Procopio, R, Iannuccelli, M, Castagnoli, L, Polo, S, Paci, M, Cesareni, G.
Deposit date:2015-09-14
Release date:2016-09-14
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Unveiling the structural determinants of KIAA0323 binding preference for NEDD8
To be Published
2N7D
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BU of 2n7d by Molmil
Solution structure of the UBL domain of human Ddi2
Descriptor: Protein DDI1 homolog 2
Authors:Siva, M, Grantz Saskova, K, Veverka, V.
Deposit date:2015-09-08
Release date:2016-07-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog.
Sci Rep, 6, 2016
5DK8
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BU of 5dk8 by Molmil
Human ubiquitin in the P1 space group
Descriptor: MAGNESIUM ION, Polyubiquitin-B
Authors:Camara-Artigas, A, Bacarizo, J.
Deposit date:2015-09-03
Release date:2015-12-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:New crystal form of human ubiquitin in the presence of magnesium.
Acta Crystallogr.,Sect.F, 72, 2016
5DFL
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BU of 5dfl by Molmil
Crystal structure of Ube2K~Ubiquitin conjugate
Descriptor: GLYCEROL, Ubiquitin, Ubiquitin-conjugating enzyme E2 K
Authors:Middleton, A.J, Day, C.L.
Deposit date:2015-08-27
Release date:2015-12-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The molecular basis of lysine 48 ubiquitin chain synthesis by Ube2K.
Sci Rep, 5, 2015
5D6J
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BU of 5d6j by Molmil
Crystal structure of a mycobacterial protein
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Acyl-CoA synthase, MAGNESIUM ION, ...
Authors:Li, W.J, Bi, L.J.
Deposit date:2015-08-12
Release date:2016-03-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of FadD32, an enzyme essential for mycolic acid biosynthesis in mycobacteria.
Sci Rep, 5, 2015
5D0K
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BU of 5d0k by Molmil
Structure of UbE2D2:RNF165:Ub complex
Descriptor: Polyubiquitin-B, RING finger protein 165, Ubiquitin-conjugating enzyme E2 D2, ...
Authors:Wright, J.D, Day, C.L, Mace, P.D.
Deposit date:2015-08-03
Release date:2015-12-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity.
Nat.Struct.Mol.Biol., 23, 2016
5D0M
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BU of 5d0m by Molmil
Structure of UbE2D2:RNF165:Ub complex
Descriptor: PHOSPHATE ION, Polyubiquitin-B, RING finger protein 165, ...
Authors:Wright, J.D, Day, C.L, Mace, P.D.
Deposit date:2015-08-03
Release date:2015-12-09
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (1.913 Å)
Cite:Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity.
Nat.Struct.Mol.Biol., 23, 2016
5CVM
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BU of 5cvm by Molmil
USP46~ubiquitin BEA covalent complex
Descriptor: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, ZINC ION
Authors:Harris, S.F, Yin, J.
Deposit date:2015-07-27
Release date:2015-10-07
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Structure, 23, 2015
5CVN
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BU of 5cvn by Molmil
WDR48 (2-580):USP46~ubiquitin ternary complex
Descriptor: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, WD repeat-containing protein 48, ...
Authors:Harris, S.F, Yin, J.
Deposit date:2015-07-27
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.36 Å)
Cite:Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Structure, 23, 2015
5CVO
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BU of 5cvo by Molmil
WDR48:USP46~ubiquitin ternary complex
Descriptor: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, WD repeat-containing protein 48, ...
Authors:Harris, S.F, Yin, J.
Deposit date:2015-07-27
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.885 Å)
Cite:Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Structure, 23, 2015
5CRA
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BU of 5cra by Molmil
Structure of the SdeA DUB Domain
Descriptor: METHYL 4-AMINOBUTANOATE, Polyubiquitin-B, SULFATE ION, ...
Authors:Sheedlo, M.J, Qiu, J, Luo, Z.Q, Das, C.
Deposit date:2015-07-22
Release date:2015-11-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural basis of substrate recognition by a bacterial deubiquitinase important for dynamics of phagosome ubiquitination.
Proc.Natl.Acad.Sci.USA, 112, 2015
5CHW
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BU of 5chw by Molmil
Structure of ISG15 in space group P212121
Descriptor: GLYCEROL, SULFATE ION, Ubiquitin-like protein ISG15
Authors:Fritz, G, Basters, A.
Deposit date:2015-07-10
Release date:2016-09-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of ISG15 in space group P212121
To Be Published
5CHF
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BU of 5chf by Molmil
Crystal structure of murine ISG15 in space group P21212
Descriptor: GLYCEROL, SULFATE ION, Ubiquitin-like protein ISG15
Authors:Fritz, G, Basters, A.
Deposit date:2015-07-10
Release date:2016-09-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of murine ISG15 in space group P21212
To Be Published
5CHV
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BU of 5chv by Molmil
Crystal structure of USP18-ISG15 complex
Descriptor: CHLORIDE ION, SULFATE ION, Ubiquitin-like protein ISG15, ...
Authors:Fritz, G, Basters, A.
Deposit date:2015-07-10
Release date:2016-09-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Structural basis of the specificity of USP18 toward ISG15.
Nat. Struct. Mol. Biol., 24, 2017
5CAW
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BU of 5caw by Molmil
Structure of Pediculus humanus Parkin bound to phospho-ubiquitin
Descriptor: E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, SULFATE ION, ...
Authors:Wauer, T, Komander, D.
Deposit date:2015-06-30
Release date:2015-07-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Mechanism of phospho-ubiquitin-induced PARKIN activation.
Nature, 524, 2015
5C7M
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BU of 5c7m by Molmil
CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT
Descriptor: E3 ubiquitin-protein ligase Itchy homolog, Polyubiquitin-C
Authors:Walker, J.R, Hu, J, Dong, A, Wernimont, A, Zhang, W, Sidhu, S, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC)
Deposit date:2015-06-24
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
5C7J
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BU of 5c7j by Molmil
CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT
Descriptor: E3 ubiquitin-protein ligase NEDD4, Polyubiquitin-C
Authors:Walker, J.R, Hu, J, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC)
Deposit date:2015-06-24
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
3JAP
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BU of 3jap by Molmil
Structure of a partial yeast 48S preinitiation complex in closed conformation
Descriptor: 18S rRNA, MAGNESIUM ION, METHIONINE, ...
Authors:Llacer, J.L, Hussain, T, Ramakrishnan, V.
Deposit date:2015-06-18
Release date:2015-08-12
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
3JAM
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BU of 3jam by Molmil
CryoEM structure of 40S-eIF1A-eIF1 complex from yeast
Descriptor: 18S rRNA, MAGNESIUM ION, RACK1, ...
Authors:Llacer, J.L, Hussain, T, Ramakrishnan, V.
Deposit date:2015-06-17
Release date:2015-08-12
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
5A5B
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BU of 5a5b by Molmil
Structure of the 26S proteasome-Ubp6 complex
Descriptor: 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ...
Authors:Aufderheide, A, Beck, F, Stengel, F, Hartwig, M, Schweitzer, A, Pfeifer, G, Goldberg, A.L, Sakata, E, Baumeister, W, Foerster, F.
Deposit date:2015-06-17
Release date:2015-07-22
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Structural Characterization of the Interaction of Ubp6 with the 26S Proteasome.
Proc.Natl.Acad.Sci.USA, 112, 2015
2N4F
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BU of 2n4f by Molmil
EC-NMR Structure of Arabidopsis thaliana At2g32350 Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data. Northeast Structural Genomics Consortium target AR3433A
Descriptor: uncharacterized protein AR3433A
Authors:Tang, Y, Huang, Y.J, Hopf, T.A, Sander, C, Marks, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-06-17
Release date:2015-07-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Protein structure determination by combining sparse NMR data with evolutionary couplings.
Nat.Methods, 12, 2015
5C23
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BU of 5c23 by Molmil
Parkin (S65DUblR0RBR)
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ...
Authors:Kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H.
Deposit date:2015-06-15
Release date:2015-07-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
5C1Z
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BU of 5c1z by Molmil
Parkin (UblR0RBR)
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ...
Authors:kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H.
Deposit date:2015-06-15
Release date:2015-07-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
5BZ0
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BU of 5bz0 by Molmil
Crystal structure of IBV papain-like protease PLpro C101S mutant in complex with ubiquitin
Descriptor: Replicase polyprotein 1ab, Ubiquitin-40S ribosomal protein S27a, ZINC ION
Authors:Kong, L.Y, Yan, L.M, Zhang, Y, Rao, Z.H.
Deposit date:2015-06-11
Release date:2016-06-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of IBV papain-like protease PLpro C101S mutant in complex with ubiquitin
To Be Published
3JAG
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BU of 3jag by Molmil
Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V.
Deposit date:2015-06-10
Release date:2015-08-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Structural basis for stop codon recognition in eukaryotes.
Nature, 524, 2015

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