2CY1
| Crystal structure of APE1850 | Descriptor: | NusA protein homolog | Authors: | Shibata, R, Bessho, Y, Umehara, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-07-04 | Release date: | 2006-01-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystallization of the archaeal transcription termination factor NusA: a significant decrease in twinning under microgravity conditions Acta Crystallogr.,Sect.F, 63, 2007
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2D0K
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2ZHP
| Crystal structure of bleomycin-binding protein from Streptoalloteichus hindustanus complexed with bleomycin derivative | Descriptor: | Bleomycin resistance protein, CHLORIDE ION, COPPER (II) ION, ... | Authors: | Okumura, H, Miyazaki, I, Simizu, S, Osada, H. | Deposit date: | 2008-02-06 | Release date: | 2009-02-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure-Affinity Relationship Study of Bleomycins and Shble protein Using a Chemical Array To be Published
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7X91
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7X8W
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7X8Z
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7X8Y
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7X90
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3AJ3
| Crystal structure of selenomethionine substituted 4-pyridoxolactonase from Mesorhizobium loti | Descriptor: | 4-pyridoxolactonase, PHOSPHATE ION, ZINC ION | Authors: | Kobayashi, J, Yoshikane, Y, Baba, S, Mikami, B, Yagi, T. | Deposit date: | 2010-05-21 | Release date: | 2011-05-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.577 Å) | Cite: | Structure of 4-pyridoxolactonase from Mesorhizobium loti. Acta Crystallogr.,Sect.F, 70, 2014
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7XGP
| Human renin in complex with compound3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, UNKNOWN LIGAND | Authors: | Kashima, A. | Deposit date: | 2022-04-05 | Release date: | 2022-09-07 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Discovery of SPH3127: A Novel, Highly Potent, and Orally Active Direct Renin Inhibitor. J.Med.Chem., 65, 2022
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2Z9S
| Crystal Structure Analysis of rat HBP23/Peroxiredoxin I, Cys52Ser mutant | Descriptor: | Peroxiredoxin-1 | Authors: | Matsumura, T, Okamoto, K, Nishino, T, Abe, Y. | Deposit date: | 2007-09-25 | Release date: | 2007-11-20 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Dimer-Oligomer Interconversion of Wild-type and Mutant Rat 2-Cys Peroxiredoxin: DISULFIDE FORMATION AT DIMER-DIMER INTERFACES IS NOT ESSENTIAL FOR DECAMERIZATION J.Biol.Chem., 283, 2008
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7XY8
| Crystal structure of antibody Fab fragment in complex with CD147(EMMPIRIN) | Descriptor: | Isoform 2 of Basigin, heavy chain, light chain | Authors: | Nakamura, K, Amano, M, Yoneda, K, Suzuki, M, Fukuchi, K. | Deposit date: | 2022-06-01 | Release date: | 2022-11-23 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Novel Antibody Exerts Antitumor Effect through Downregulation of CD147 and Activation of Multiple Stress Signals. J Oncol, 2022, 2022
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7YI7
| Crystal structure of Human HPSE1 in complex with inhibitor | Descriptor: | (5~{S},6~{R},7~{S},8~{S})-6,7,8-tris(oxidanyl)-2-[2-[4-(trifluoromethyl)phenyl]ethyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid, Heparanase 50 kDa subunit, Heparanase 8 kDa subunit | Authors: | Mima, M, Fujimoto, N, Imai, Y. | Deposit date: | 2022-07-15 | Release date: | 2022-12-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Lead identification of novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid derivative as a potent heparanase-1 inhibitor. Bioorg.Med.Chem.Lett., 79, 2022
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7YJC
| Crystal structure of Human HPSE1 in complex with inhibitor | Descriptor: | (5~{S},6~{R},7~{S},8~{S})-6,7,8-tris(oxidanyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid, Heparanase 50 kDa subunit, Heparanase 8 kDa subunit | Authors: | Mima, M, Fujimoto, N, Imai, Y. | Deposit date: | 2022-07-19 | Release date: | 2022-12-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Lead identification of novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid derivative as a potent heparanase-1 inhibitor. Bioorg.Med.Chem.Lett., 79, 2022
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2ZK9
| Crystal Structure of Protein-glutaminase | Descriptor: | GLYCEROL, Protein-glutaminase, SODIUM ION | Authors: | Hashizume, R. | Deposit date: | 2008-03-13 | Release date: | 2009-03-17 | Last modified: | 2012-08-29 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Crystal structures of protein glutaminase and its pro forms converted into enzyme-substrate complex J.Biol.Chem., 286, 2011
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3A55
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2DDT
| Crystal structure of sphingomyelinase from Bacillus cereus with magnesium ion | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, SULFATE ION, ... | Authors: | Ago, H, Oda, M, Tsuge, H, Katunuma, N, Miyano, M, Sakurai, J, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-02-02 | Release date: | 2006-05-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of the sphingomyelin phosphodiesterase activity in neutral sphingomyelinase from Bacillus cereus. J.Biol.Chem., 281, 2006
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3A54
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2DK4
| Solution structure of Splicing Factor Motif in Pre-mRNA splicing factor 18 (hPRP18) | Descriptor: | Pre-mRNA-splicing factor 18 | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-06 | Release date: | 2006-10-06 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the splicing factor motif of the human Prp18 protein. Proteins, 80, 2012
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2E1T
| Crystal structure of Dendranthema morifolium DmAT complexed with malonyl-CoA | Descriptor: | MALONYL-COENZYME A, acyl transferase | Authors: | Unno, H, Ichimaida, F, Kusunoki, M, Nakayama, T. | Deposit date: | 2006-10-28 | Release date: | 2007-04-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and Mutational Studies of Anthocyanin Malonyltransferases Establish the Features of BAHD Enzyme Catalysis J.Biol.Chem., 282, 2007
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5WXI
| EarP bound with dTDP-rhamnose (soaked) | Descriptor: | 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, BETA-MERCAPTOETHANOL, EarP, ... | Authors: | Sengoku, T, Yokoyama, S, Yanagisawa, T. | Deposit date: | 2017-01-07 | Release date: | 2018-02-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of protein arginine rhamnosylation by glycosyltransferase EarP Nat. Chem. Biol., 14, 2018
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5WXJ
| Apo EarP | Descriptor: | BETA-MERCAPTOETHANOL, EarP, GLYCEROL, ... | Authors: | Sengoku, T, Yokoyama, S, Yanagisawa, T. | Deposit date: | 2017-01-07 | Release date: | 2018-02-28 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis of protein arginine rhamnosylation by glycosyltransferase EarP Nat. Chem. Biol., 14, 2018
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5WXK
| EarP bound with domain I of EF-P | Descriptor: | BETA-MERCAPTOETHANOL, EarP, Elongation factor P, ... | Authors: | Sengoku, T, Yokoyama, S, Yanagisawa, T. | Deposit date: | 2017-01-07 | Release date: | 2018-02-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | Structural basis of protein arginine rhamnosylation by glycosyltransferase EarP Nat. Chem. Biol., 14, 2018
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5X4A
| SLL-2-Forssman antigen tetrasaccharides complex | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Galactose-binding lectin, ... | Authors: | Kita, A, Miki, K. | Deposit date: | 2017-02-11 | Release date: | 2017-09-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Crystal structure of octocoral lectin SLL-2 complexed with Forssman antigen tetrasaccharide. Glycobiology, 2017
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5XMX
| Co-crystal structure of Inhibitor compound in complex with human PPARdelta LBD | Descriptor: | (E)-6-[2-[[[4-(furan-2-yl)phenyl]carbonyl-methyl-amino]methyl]phenoxy]-4-methyl-hex-4-enoic acid, Peroxisome proliferator-activated receptor delta | Authors: | Lakshminarasimhan, A, Rani, S.T, Senaiar, R.S, Krishnamurthy, N. | Deposit date: | 2017-05-16 | Release date: | 2018-05-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Novel highly selective peroxisome proliferator-activated receptor delta (PPAR delta) modulators with pharmacokinetic properties suitable for once-daily oral dosing. Bioorg. Med. Chem. Lett., 27, 2017
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