7XY8

Crystal structure of antibody Fab fragment in complex with CD147(EMMPIRIN)

Summary for 7XY8

• Entry DOI: 10.2210/pdb7xy8/pdb
• Descriptor: Isoform 2 of Basigin, heavy chain, light chain, ... (4 entities in total)
• Functional Keywords: cd147, complex, antibody, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 142428.30

Authors

Nakamura, K.,Amano, M.,Yoneda, K.,Suzuki, M.,Fukuchi, K. (deposition date: 2022-06-01, release date: 2022-11-23, Last modification date: 2023-11-29)

• Primary citation: Qin, S.,Fukuchi, K.,Nanai, K.,Yuita, H.,Maru, C.,Tsukada, J.,Ishigami, M.,Nagai, Y.,Nakano, Y.,Yoshimura, C.,Yoneda, K.,Amano, M.,Nakamura, K.,Oda, Y.,Nishigohri, H.,Yamamoto, S.,Ohnishi-Totoki, Y.,Inaki, K.,Komori, H.,Nakano, R.,Kanari, Y.,Nishida, A.,Matsui, Y.,Funo, S.,Takahashi, S.,Ohtsuka, T.,Agatsuma, T.; Novel Antibody Exerts Antitumor Effect through Downregulation of CD147 and Activation of Multiple Stress Signals; J Oncol, 2022:3552793-, 2022; DOI: 10.1155/2022/3552793

Experimental method

X-RAY DIFFRACTION (2.3 Å)