7XY8
Crystal structure of antibody Fab fragment in complex with CD147(EMMPIRIN)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Isoform 2 of Basigin | polymer | 205 | 22503.9 | 2 | UniProt (P35613) Pfam (PF13927) In PDB | Homo sapiens (human) | 5F7,Collagenase stimulatory factor,Extracellular matrix metalloproteinase inducer,EMMPRIN,Hepatoma-associated antigen,HAb18G,Leukocyte activation antigen M6,OK blood group antigen,Tumor cell-derived collagenase stimulatory factor,TCSF |
2 | H, I | heavy chain | polymer | 236 | 25277.3 | 2 | synthetic construct | ||
3 | L, M | light chain | polymer | 214 | 23432.9 | 2 | synthetic construct | ||
4 | water | water | 18.0 | 187 | Chemie (HOH) |
Sequence modifications
A, B: 22 - 205 (UniProt: P35613)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Gly 2 | - | expression tag |
Ser 3 | - | expression tag |
Ser 4 | - | expression tag |
His 5 | - | expression tag |
His 6 | - | expression tag |
His 7 | - | expression tag |
His 8 | - | expression tag |
His 9 | - | expression tag |
His 10 | - | expression tag |
Ser 11 | - | expression tag |
Ser 12 | - | expression tag |
Gly 13 | - | expression tag |
Glu 14 | - | expression tag |
Asn 15 | - | expression tag |
Leu 16 | - | expression tag |
Tyr 17 | - | expression tag |
Phe 18 | - | expression tag |
Gln 19 | - | expression tag |
Gly 20 | - | expression tag |
Ser 21 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 142428.3 | |
All* | Total formula weight | 142428.3 |