2D0K

Methionine-free mutant of Escherichia coli dihydrofolate reductase

Summary for 2D0K

Entry DOI	10.2210/pdb2d0k/pdb
Descriptor	Dihydrofolate reductase, CHLORIDE ION, FOLIC ACID, ... (4 entities in total)
Functional Keywords	alpha + beta, oxidoreductase, structural genomics
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	36801.54
Authors	Katayanagi, K. (deposition date: 2005-08-04, release date: 2006-02-28, Last modification date: 2023-10-25)
Primary citation	Iwakura, M.,Maki, K.,Takahashi, H.,Takenawa, T.,Yokota, A.,Katayanagi, K.,Kamiyama, T.,Gekko, K. Evolutional Design of a Hyperactive Cysteine- and Methionine-free Mutant of Escherichia coli Dihydrofolate Reductase J.Biol.Chem., 281:13234-13246, 2006 Cited by PubMed: 16510443 DOI: 10.1074/jbc.M508823200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation