2D0K
Methionine-free mutant of Escherichia coli dihydrofolate reductase
Summary for 2D0K
Entry DOI | 10.2210/pdb2d0k/pdb |
Descriptor | Dihydrofolate reductase, CHLORIDE ION, FOLIC ACID, ... (4 entities in total) |
Functional Keywords | alpha + beta, oxidoreductase, structural genomics |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 36801.54 |
Authors | Katayanagi, K. (deposition date: 2005-08-04, release date: 2006-02-28, Last modification date: 2023-10-25) |
Primary citation | Iwakura, M.,Maki, K.,Takahashi, H.,Takenawa, T.,Yokota, A.,Katayanagi, K.,Kamiyama, T.,Gekko, K. Evolutional Design of a Hyperactive Cysteine- and Methionine-free Mutant of Escherichia coli Dihydrofolate Reductase J.Biol.Chem., 281:13234-13246, 2006 Cited by PubMed: 16510443DOI: 10.1074/jbc.M508823200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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