7KUG
| Fe-S cluster-bound transcription activator WhiB7 in complex with the SigmaAr4-RNAP Beta flap tip chimera | Descriptor: | IRON/SULFUR CLUSTER, Probable transcriptional regulator WhiB7, RNA polymerase sigma factor, ... | Authors: | Wan, T, Horova, M, Beltran, D.G, Li, S.R, Zhang, L.M. | Deposit date: | 2020-11-24 | Release date: | 2021-06-30 | Last modified: | 2021-10-06 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural insights into the functional divergence of WhiB-like proteins in Mycobacterium tuberculosis. Mol.Cell, 81, 2021
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7EYD
| Cryo-EM structure of cyanobacterial phycobilisome from Anabaena sp. PCC 7120 | Descriptor: | Allophycocyanin subunit alpha 1, Allophycocyanin subunit alpha-B, Allophycocyanin subunit beta, ... | Authors: | Zheng, L, Zheng, Z, Li, X, Wang, G, Zhang, K, Wei, P, Zhao, J, Gao, N. | Deposit date: | 2021-05-30 | Release date: | 2021-10-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural insight into the mechanism of energy transfer in cyanobacterial phycobilisomes. Nat Commun, 12, 2021
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7KUF
| Transcription activation subcomplex with WhiB7 bound to SigmaAr4-RNAP Beta flap tip chimera and DNA | Descriptor: | DNA (5'-D(*CP*AP*GP*AP*AP*AP*AP*TP*CP*GP*GP*TP*TP*GP*TP*GP*GP*T)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*AP*AP*CP*CP*GP*AP*TP*TP*TP*TP*CP*T)-3'), IRON/SULFUR CLUSTER, ... | Authors: | Wan, T, Horova, M, Beltran, D.G, Li, S.R, Zhang, L.M. | Deposit date: | 2020-11-24 | Release date: | 2021-06-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insights into the functional divergence of WhiB-like proteins in Mycobacterium tuberculosis. Mol.Cell, 81, 2021
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6P38
| Crystal Structure Analysis of TAF1 Bromodomain | Descriptor: | 4-{[(3R)-4-cyclopentyl-1,3-dimethyl-2-oxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-6-yl]amino}-N-(1-methylpiperidin-4-yl)-3-[(propan-2-yl)oxy]benzamide, Transcription initiation factor TFIID subunit 1 | Authors: | Seo, H.-S, Dhe-Paganon, S. | Deposit date: | 2019-05-23 | Release date: | 2020-05-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Dual Inhibition of TAF1 and BET Bromodomains from the BI-2536 Kinase Inhibitor Scaffold. Acs Med.Chem.Lett., 10, 2019
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3OXE
| crystal structure of glycine riboswitch, Mn2+ soaked | Descriptor: | GLYCINE, MAGNESIUM ION, MANGANESE (II) ION, ... | Authors: | Huang, L, Serganov, A, Patel, D.J. | Deposit date: | 2010-09-21 | Release date: | 2010-12-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.899 Å) | Cite: | Structural insights into ligand recognition by a sensing domain of the cooperative glycine riboswitch. Mol.Cell, 40, 2010
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1SL5
| Crystal Structure of DC-SIGN carbohydrate recognition domain complexed with LNFP III (Dextra L504). | Descriptor: | CALCIUM ION, MAGNESIUM ION, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, ... | Authors: | Guo, Y, Feinberg, H, Conroy, E, Mitchell, D.A, Alvarez, R, Blixt, O, Taylor, M.E, Weis, W.I, Drickamer, K. | Deposit date: | 2004-03-05 | Release date: | 2004-06-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for distinct ligand-binding and targeting properties of the receptors
DC-SIGN and DC-SIGNR Nat.Struct.Mol.Biol., 11, 2004
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1SKW
| Binary 3' complex of T7 DNA polymerase with a DNA primer/template containing a disordered cis-syn thymine dimer on the template | Descriptor: | 5'-D(*CP*CP*CP*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*C*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*(2DT))-3', DNA polymerase, ... | Authors: | Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T. | Deposit date: | 2004-03-05 | Release date: | 2004-07-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7. Nat.Struct.Mol.Biol., 11, 2004
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1RXX
| Structure of arginine deiminase | Descriptor: | Arginine deiminase | Authors: | Galkin, A, Kulakova, L, Sarikaya, E, Lim, K, Howard, A, Herzberg, O, Structure 2 Function Project (S2F) | Deposit date: | 2003-12-18 | Release date: | 2004-01-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural insight into arginine degradation by arginine deiminase, an antibacterial and parasite drug target. J.Biol.Chem., 279, 2004
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1SQT
| Substituted 2-Naphthamidine Inhibitors of Urokinase | Descriptor: | 7-METHOXY-8-[1-(METHYLSULFONYL)-1H-PYRAZOL-4-YL]NAPHTHALENE-2-CARBOXIMIDAMIDE, Urokinase-type plasminogen activator | Authors: | Wendt, M.D, Geyer, A, McClellan, W.J, Rockway, T.W, Weitzberg, M, Zhang, X, Mantei, R, Stewart, K, Nienaber, V, Klinghofer, V, Giranda, V.L. | Deposit date: | 2004-03-19 | Release date: | 2004-04-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Interaction with the S1beta-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors. Bioorg.Med.Chem.Lett., 14, 2004
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6PIF
| V. cholerae TniQ-Cascade complex, open conformation | Descriptor: | Cas7, type I-F CRISPR-associated protein, TniQ monomer 1, ... | Authors: | Halpin-Healy, T, Klompe, S, Sternberg, S.H. | Deposit date: | 2019-06-26 | Release date: | 2019-10-02 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system. Nature, 577, 2020
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3OVJ
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3WJF
| Crystal structure of mutant nitrobindin M75L/H76L/Q96C/V128W/M148L/H158L (NB9) from Arabidopsis thaliana | Descriptor: | UPF0678 fatty acid-binding protein-like protein At1g79260 | Authors: | Mizohata, E, Fukumoto, K, Onoda, A, Bocola, M, Arlt, M, Inoue, T, Schwaneberg, U, Hayashi, T. | Deposit date: | 2013-10-08 | Release date: | 2014-04-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A Rhodium Complex-linked Hybrid Biocatalyst: Stereo-controlled Phenylacetylene Polymerization within an Engineered Protein Cavity CHEMCATCHEM, 2014
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3OWZ
| Crystal structure of glycine riboswitch, soaked in Iridium | Descriptor: | Domain II of glycine riboswitch, GLYCINE, IRIDIUM HEXAMMINE ION, ... | Authors: | Huang, L, Serganov, A, Patel, D.J. | Deposit date: | 2010-09-20 | Release date: | 2010-12-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.949 Å) | Cite: | Structural insights into ligand recognition by a sensing domain of the cooperative glycine riboswitch. Mol.Cell, 40, 2010
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6F3T
| Crystal structure of the human TAF5-TAF6-TAF9 complex | Descriptor: | CHLORIDE ION, Transcription initiation factor TFIID subunit 5, Transcription initiation factor TFIID subunit 6, ... | Authors: | Haffke, M, Berger, I. | Deposit date: | 2017-11-28 | Release date: | 2018-12-05 | Last modified: | 2018-12-19 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Chaperonin CCT checkpoint function in basal transcription factor TFIID assembly. Nat. Struct. Mol. Biol., 25, 2018
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1TV2
| Crystal structure of the hydroxylamine MtmB complex | Descriptor: | 5-HYDROXYAMINO-3-METHYL-PYRROLIDINE-2-CARBOXYLIC ACID, Monomethylamine methyltransferase mtmB1 | Authors: | Hao, B, Zhao, G, Kang, P.T, Soares, J.A, Ferguson, T.K, Gallucci, J, Krzycki, J.A, Chan, M.K. | Deposit date: | 2004-06-26 | Release date: | 2004-10-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Reactivity and chemical synthesis of L-pyrrolysine- the 22(nd) genetically encoded amino acid Chem.Biol., 11, 2004
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6PGP
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1TWC
| RNA polymerase II complexed with GTP | Descriptor: | DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ... | Authors: | Westover, K.D, Bushnell, D.A, Kornberg, R.D. | Deposit date: | 2004-06-30 | Release date: | 2004-11-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center. Cell(Cambridge,Mass.), 119, 2004
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6F20
| Complex between MTH1 and compound 1 (a 7-azaindole-4-ester derivative) | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, ACETATE ION, Ethyl 1H-pyrrolo[2,3-b]pyridine-4-carboxylate, ... | Authors: | Viklund, J, Talagas, A, Tresaugues, L, Andersson, M, Ericsson, U, Forsblom, R, Ginman, T, Hallberg, K, Lindstrom, J, Persson, L, Silvander, C, Rahm, F. | Deposit date: | 2017-11-23 | Release date: | 2018-03-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design. J. Med. Chem., 61, 2018
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1TWA
| RNA polymerase II complexed with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, ... | Authors: | Westover, K.D, Bushnell, D.A, Kornberg, R.D. | Deposit date: | 2004-06-30 | Release date: | 2004-11-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center. Cell(Cambridge,Mass.), 119, 2004
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3WJG
| Crystal structure of mutant nitrobindin M75L/H76L/Q96C/M148W/H158L (NB10) from Arabidopsis thaliana | Descriptor: | GLYCEROL, UPF0678 fatty acid-binding protein-like protein At1g79260 | Authors: | Mizohata, E, Fukumoto, K, Onoda, A, Bocola, M, Arlt, M, Inoue, T, Schwaneberg, U, Hayashi, T. | Deposit date: | 2013-10-08 | Release date: | 2014-04-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | A Rhodium Complex-linked Hybrid Biocatalyst: Stereo-controlled Phenylacetylene Polymerization within an Engineered Protein Cavity CHEMCATCHEM, 2014
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6F6N
| CRYSTAL STRUCTURE OF EBOLAVIRUS GLYCOPROTEIN IN COMPLEX WITH SERTRALINE | Descriptor: | (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | Authors: | Ren, J, Zhao, Y, Fry, E.E, Stuart, D.I. | Deposit date: | 2017-12-05 | Release date: | 2018-01-03 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Target Identification and Mode of Action of Four Chemically Divergent Drugs against Ebolavirus Infection. J. Med. Chem., 61, 2018
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3OVL
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6P95
| Structure of Lassa virus glycoprotein in complex with Fab 25.6A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Saphire, E.O, Hastie, K.M. | Deposit date: | 2019-06-09 | Release date: | 2019-09-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Convergent Structures Illuminate Features for Germline Antibody Binding and Pan-Lassa Virus Neutralization. Cell, 178, 2019
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3OXB
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3OXM
| crystal structure of glycine riboswitch, Tl-Acetate soaked | Descriptor: | GLYCINE, MAGNESIUM ION, THALLIUM (I) ION, ... | Authors: | Huang, L, Serganov, A, Patel, D.J. | Deposit date: | 2010-09-21 | Release date: | 2010-12-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural insights into ligand recognition by a sensing domain of the cooperative glycine riboswitch. Mol.Cell, 40, 2010
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