2RLJ
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![BU of 2rlj by Molmil](/molmil-images/mine/2rlj) | NMR Structure of Ebola fusion peptide in SDS micelles at pH 7 | Descriptor: | Envelope glycoprotein | Authors: | Freitas, M.S, Gaspar, L.P, Lorenzoni, M, Almeida, F.C, Tinoco, L.W, Almeida, M.S, Maia, L.F, Degreve, L, Valente, A.P, Silva, J.L. | Deposit date: | 2007-07-05 | Release date: | 2007-08-07 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of the Ebola fusion peptide in a membrane-mimetic environment and the interaction with lipid rafts. J.Biol.Chem., 282, 2007
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2TRC
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![BU of 2trc by Molmil](/molmil-images/mine/2trc) | PHOSDUCIN/TRANSDUCIN BETA-GAMMA COMPLEX | Descriptor: | GADOLINIUM ATOM, PHOSDUCIN, TRANSDUCIN | Authors: | Gaudet, R, Bohm, A, Sigler, P.B. | Deposit date: | 1997-01-06 | Release date: | 1997-06-05 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin. Cell(Cambridge,Mass.), 87, 1996
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6IP8
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![BU of 6ip8 by Molmil](/molmil-images/mine/6ip8) | Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | Deposit date: | 2018-11-02 | Release date: | 2019-05-29 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | HCV IRES Captures an Actively Translating 80S Ribosome. Mol.Cell, 74, 2019
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6ID1
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![BU of 6id1 by Molmil](/molmil-images/mine/6id1) | Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | Authors: | Zhang, X, Zhan, X, Yan, C, Shi, Y. | Deposit date: | 2018-09-07 | Release date: | 2019-03-13 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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6I7O
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![BU of 6i7o by Molmil](/molmil-images/mine/6i7o) | The structure of a di-ribosome (disome) as a unit for RQC and NGD quality control pathways recognition. | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Tesina, P, Cheng, J, Becker, T, Beckmann, R. | Deposit date: | 2018-11-16 | Release date: | 2019-01-16 | Last modified: | 2019-03-13 | Method: | ELECTRON MICROSCOPY (5.3 Å) | Cite: | Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways. EMBO J., 38, 2019
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8Q1N
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![BU of 8q1n by Molmil](/molmil-images/mine/8q1n) | Cyclic peptide binder of the WBM-site of WDR5 | Descriptor: | Cyclic peptide inhibitor, WD repeat-containing protein 5 | Authors: | Schmeing, S, Chang, J.Y, t Hart, P, Gasper, R. | Deposit date: | 2023-08-01 | Release date: | 2023-09-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.843 Å) | Cite: | Macrocyclic peptides as inhibitors of WDR5-lncRNA interactions. Chem.Commun.(Camb.), 59, 2023
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6IP5
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![BU of 6ip5 by Molmil](/molmil-images/mine/6ip5) | Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | Deposit date: | 2018-11-02 | Release date: | 2019-05-29 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | HCV IRES Captures an Actively Translating 80S Ribosome. Mol.Cell, 74, 2019
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2VGB
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![BU of 2vgb by Molmil](/molmil-images/mine/2vgb) | HUMAN ERYTHROCYTE PYRUVATE KINASE | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, 2-PHOSPHOGLYCOLIC ACID, MANGANESE (II) ION, ... | Authors: | Valentini, G, Chiarelli, L, Fortin, R, Dolzan, M, Galizzi, A, Abraham, D.J, Wang, C, Bianchi, P, Zanella, A, Mattevi, A. | Deposit date: | 2007-11-12 | Release date: | 2007-11-20 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Structure and Function of Human Erythrocyte Pyruvate Kinase. Molecular Basis of Nonspherocytic Hemolytic Anemia. J.Biol.Chem., 277, 2002
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8P2F
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![BU of 8p2f by Molmil](/molmil-images/mine/8p2f) | Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid cyclopentane in post-translocational state | Descriptor: | 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 2-[(3~{R},4~{S},5~{S},8~{S},9~{S},10~{S},11~{R},13~{S},14~{S},16~{S})-16-acetyloxy-4,8,10,14-tetramethyl-3,11-bis(oxidanyl)-1,2,3,4,5,6,7,9,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5-cyclopentyl-pentanoic acid, ... | Authors: | Gonzalez-Lopez, A, Selmer, M. | Deposit date: | 2023-05-16 | Release date: | 2024-05-01 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.44 Å) | Cite: | Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane. Sci Rep, 14, 2024
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8P2G
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![BU of 8p2g by Molmil](/molmil-images/mine/8p2g) | Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid cyclopentane with a tRNA in pe/E chimeric state | Descriptor: | 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 2-[(3~{R},4~{S},5~{S},8~{S},9~{S},10~{S},11~{R},13~{S},14~{S},16~{S})-16-acetyloxy-4,8,10,14-tetramethyl-3,11-bis(oxidanyl)-1,2,3,4,5,6,7,9,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5-cyclopentyl-pentanoic acid, ... | Authors: | Gonzalez-Lopez, A, Selmer, M. | Deposit date: | 2023-05-16 | Release date: | 2024-05-01 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.02 Å) | Cite: | Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane. Sci Rep, 14, 2024
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8P2H
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![BU of 8p2h by Molmil](/molmil-images/mine/8p2h) | |
8OVJ
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![BU of 8ovj by Molmil](/molmil-images/mine/8ovj) | CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : PARENTAL STRAIN | Descriptor: | 40S ribosomal protein S12, 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, ... | Authors: | Rajan, K.S, Yonath, A. | Deposit date: | 2023-04-26 | Release date: | 2024-05-08 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. Cell Rep, 43, 2024
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8PJK
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![BU of 8pjk by Molmil](/molmil-images/mine/8pjk) | ST171-bound serotonin 5-HT1A receptor - Gi Protein Complex | Descriptor: | (2R)-1-(heptadecanoyloxy)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 5-hydroxytryptamine receptor 1A, 6-[3-[2-(2-methoxyphenoxy)ethylamino]propoxy]-4~{H}-1,4-benzoxazin-3-one, ... | Authors: | Schneider, J, Gmeiner, P, Rasmussen, T, Boettcher, B. | Deposit date: | 2023-06-23 | Release date: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Discovery of a functionally selective serotonin 1A receptor agonist
for the treatment of pain To Be Published
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3B6J
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![BU of 3b6j by Molmil](/molmil-images/mine/3b6j) | WrbA from Escherichia coli, NADH complex | Descriptor: | ADENOSINE MONOPHOSPHATE, FLAVIN MONONUCLEOTIDE, Flavoprotein wrbA, ... | Authors: | Andrade, S.L.A, Patridge, E.V, Ferry, J.G, Einsle, O. | Deposit date: | 2007-10-29 | Release date: | 2007-12-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of the NADH:quinone oxidoreductase WrbA from Escherichia coli. J.Bacteriol., 189, 2007
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2V37
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![BU of 2v37 by Molmil](/molmil-images/mine/2v37) | Solution structure of the N-terminal extracellular domain of human T- cadherin | Descriptor: | CADHERIN-13 | Authors: | Dames, S.A, Bang, E.J, Ahrens, T, Haeussinger, D, Grzesiek, S. | Deposit date: | 2007-06-13 | Release date: | 2008-06-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Insights into the low adhesive capacity of human T-cadherin from the NMR structure of Its N-terminal extracellular domain. J. Biol. Chem., 283, 2008
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6JWN
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![BU of 6jwn by Molmil](/molmil-images/mine/6jwn) | |
8QCA
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![BU of 8qca by Molmil](/molmil-images/mine/8qca) | CryoEM structure of a S. Cerevisiae Ski2387 complex in the closed state bound to RNA | Descriptor: | Antiviral helicase SKI2, Antiviral protein SKI8, RNA (5'-R(P*UP*UP*UP*U)-3'), ... | Authors: | Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E. | Deposit date: | 2023-08-25 | Release date: | 2023-11-15 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly. Mol.Cell, 83, 2023
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6HJY
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![BU of 6hjy by Molmil](/molmil-images/mine/6hjy) | X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) Delta8 truncation mutant in complex with nanobody 72 | Descriptor: | Cys-loop ligand-gated ion channel, nanobody 72 | Authors: | Spurny, R, Govaerts, C, Evans, G.L, Pardon, E, Steyaert, J, Ulens, C. | Deposit date: | 2018-09-04 | Release date: | 2019-10-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | A lipid site shapes the agonist response of a pentameric ligand-gated ion channel. Nat.Chem.Biol., 15, 2019
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8P5D
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![BU of 8p5d by Molmil](/molmil-images/mine/8p5d) | Spraguea lophii ribosome in the closed conformation by cryo sub tomogram averaging | Descriptor: | 40S Ribosomal protein S19, 40S ribosomal protein S0, 40S ribosomal protein S10, ... | Authors: | Gil Diez, P, McLaren, M, Isupov, M.N, Daum, B, Conners, R, Williams, B. | Deposit date: | 2023-05-23 | Release date: | 2023-06-21 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (10.8 Å) | Cite: | CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state. Nat Microbiol, 8, 2023
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8P60
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![BU of 8p60 by Molmil](/molmil-images/mine/8p60) | Spraguea lophii ribosome dimer | Descriptor: | 40S Ribosomal protein S19, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | Authors: | Gil Diez, P, McLaren, M, Isupov, M.N, Daum, B, Conners, R, Williams, B. | Deposit date: | 2023-05-24 | Release date: | 2023-06-21 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (14.3 Å) | Cite: | CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state. Nat Microbiol, 8, 2023
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6GZ5
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![BU of 6gz5 by Molmil](/molmil-images/mine/6gz5) | tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-3 (TI-POST-3) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | Authors: | Flis, J, Holm, M, Rundlet, E.J, Loerke, J, Hilal, T, Dabrowski, M, Buerger, J, Mielke, T, Blanchard, S.C, Spahn, C.M.T, Budkevich, T.V. | Deposit date: | 2018-07-03 | Release date: | 2018-12-05 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis. Cell Rep, 25, 2018
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2W9R
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![BU of 2w9r by Molmil](/molmil-images/mine/2w9r) | Structural basis of N-end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS | Descriptor: | ATP-DEPENDENT CLP PROTEASE ADAPTER PROTEIN CLPS, DNA PROTECTION DURING STARVATION PROTEIN | Authors: | Schuenemann, V, Kralik, S.M, Albrecht, R, Spall, S.K, Truscott, K.N, Dougan, D.A, Zeth, K. | Deposit date: | 2009-01-28 | Release date: | 2009-04-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis of N-End Rule Substrate Recognition in Escherichia Coli by the Clpap Adaptor Protein Clps. Embo Rep., 10, 2009
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8PPL
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![BU of 8ppl by Molmil](/molmil-images/mine/8ppl) | MERS-CoV Nsp1 bound to the human 43S pre-initiation complex | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N. | Deposit date: | 2023-07-07 | Release date: | 2023-10-18 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.65 Å) | Cite: | Universal features of Nsp1-mediated translational shutdown by coronaviruses. Mol.Cell, 83, 2023
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8PPK
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![BU of 8ppk by Molmil](/molmil-images/mine/8ppk) | Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N. | Deposit date: | 2023-07-07 | Release date: | 2023-10-18 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Universal features of Nsp1-mediated translational shutdown by coronaviruses. Mol.Cell, 83, 2023
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8QCB
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![BU of 8qcb by Molmil](/molmil-images/mine/8qcb) | CryoEM structure of a S. Cerevisiae Ski2387 complex in the open state | Descriptor: | Antiviral helicase SKI2, Antiviral protein SKI8, Superkiller protein 3, ... | Authors: | Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E. | Deposit date: | 2023-08-25 | Release date: | 2023-11-08 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly. Mol.Cell, 83, 2023
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