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1J3E
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Crystal Structure of the E.coli SeqA protein complexed with N6-methyladenine- guanine mismatch DNA
Descriptor: 5'-D(*AP*AP*GP*GP*(6MA)P*TP*CP*CP*AP*A)-3', 5'-D(*TP*TP*GP*GP*AP*GP*CP*CP*TP*T)-3', SeqA protein
Authors:Fujikawa, N, Kurumizaka, H, Nureki, O, Tanaka, Y, Yamazoe, M, Hiraga, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-01-24
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and biochemical analyses of hemimethylated DNA binding by the SeqA protein
Nucleic Acids Res., 32, 2004
2ZXO
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Crystal structure of RecJ from Thermus thermophilus HB8
Descriptor: Single-stranded DNA specific exonuclease RecJ
Authors:Wakamatsu, T, Kitamura, Y, Nakagawa, N, Masui, R, Kuramitsu, S.
Deposit date:2009-01-05
Release date:2010-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of RecJ exonuclease defines its specificity for single-stranded DNA
J.Biol.Chem., 285, 2010
3FK2
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BU of 3fk2 by Molmil
Crystal structure of the RhoGAP domain of human glucocorticoid receptor DNA-binding factor 1
Descriptor: Glucocorticoid receptor DNA-binding factor 1, UNKNOWN ATOM OR ION
Authors:Nedyalkova, L, Tong, Y, Tempel, W, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2008-12-15
Release date:2008-12-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the RhoGAP domain of human glucocorticoid receptor DNA-binding factor 1
To be Published
7QB3
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BU of 7qb3 by Molmil
Solution structure of a lanthanide-binding DNA aptamer
Descriptor: LUTETIUM (III) ION, Lanthanide-binding aptamer
Authors:Andralojc, W, Gdaniec, Z.
Deposit date:2021-11-18
Release date:2021-12-01
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Solution Structure of a Lanthanide-binding DNA Aptamer Determined Using High Quality pseudocontact shift restraints.
Chemistry, 28, 2022
2ZXP
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BU of 2zxp by Molmil
Crystal structure of RecJ in complex with Mn2+ from Thermus thermophilus HB8
Descriptor: MANGANESE (II) ION, Single-stranded DNA specific exonuclease RecJ
Authors:Wakamatsu, T, Kitamura, Y, Nakagawa, N, Masui, R, Kuramitsu, S.
Deposit date:2009-01-05
Release date:2010-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of RecJ exonuclease defines its specificity for single-stranded DNA
J.Biol.Chem., 285, 2010
4MGT
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ALKBH2 R110A cross-linked to undamaged dsDNA
Descriptor: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA1, DNA2, ...
Authors:Chen, B, Gan, J, Yang, C.G.
Deposit date:2013-08-28
Release date:2014-02-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The complex structures of ALKBH2 mutants cross-linked to dsDNA reveal the conformational swing of β-hairpin
Sci China Chem, 57, 2014
3EY1
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BU of 3ey1 by Molmil
A Conformational Transition in the Structure of a 2'-Thiomethyl-Modified DNA Visualized at High Resolution
Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*(USM)P*(USM)P*CP*GP*CP*G)-3', GLYCEROL, Ribonuclease H
Authors:Egli, M, Pallan, P.S.
Deposit date:2008-10-17
Release date:2009-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A conformational transition in the structure of a 2'-thiomethyl-modified DNA visualized at high resolution.
Chem.Commun.(Camb.), 15, 2009
5YTZ
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BU of 5ytz by Molmil
Crystal structure of echinomycin-d(ACGTCGT)2 complex
Descriptor: 2-CARBOXYQUINOXALINE, DNA (5'-D(P*AP*CP*GP*TP*CP*GP*(UD))-3'), Echinomycin, ...
Authors:Hou, M.H, Wu, P.C, Kao, Y.F.
Deposit date:2017-11-20
Release date:2018-05-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Cooperative recognition of T:T mismatch by echinomycin causes structural distortions in DNA duplex
Nucleic Acids Res., 46, 2018
5YZE
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Crystal structure of the [Co2+-(chromomycin A3)2]-d(CCG)3 complex
Descriptor: (1S)-5-deoxy-1-O-methyl-1-C-[(2R,3S)-3,5,7,10-tetrahydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl]-D-xylulose, 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose-(1-3)-(2R,3R,6R)-6-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate, 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol, ...
Authors:Hou, M.H, Chen, Y.W, Wu, P.C, Satange, R.B.
Deposit date:2017-12-14
Release date:2018-10-17
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:CoII(Chromomycin)2 Complex Induces a Conformational Change of CCG Repeats from i-Motif to Base-Extruded DNA Duplex
Int J Mol Sci, 19, 2018
8VX9
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BU of 8vx9 by Molmil
Structure of HamAB apo complex from the Escherichia coli Hachiman defense system
Descriptor: HamA, HamB
Authors:Tuck, O.T, Doudna, J.A.
Deposit date:2024-02-03
Release date:2024-03-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Hachiman is a genome integrity sensor.
Biorxiv, 2024
4QQZ
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BU of 4qqz by Molmil
Crystal structure of T. fusca Cas3-AMPPNP
Descriptor: CRISPR-associated helicase, Cas3 family, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
Authors:Ke, A, Huo, Y, Nam, K.H.
Deposit date:2014-06-30
Release date:2014-08-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
1OUO
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BU of 1ouo by Molmil
Crystal structure of the periplasmic endonuclease Vvn
Descriptor: MAGNESIUM ION, Nuclease
Authors:Yuan, H.S, Li, C.L.
Deposit date:2003-03-25
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:DNA binding and cleavage by the periplasmic nuclease Vvn: a novel structure with a known active site.
Embo J., 22, 2003
4M61
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BU of 4m61 by Molmil
Crystal structure of unliganded anti-DNA Fab A52
Descriptor: Fab A52 heavy chain, Fab A52 light chain, SULFATE ION
Authors:Stanfield, R.L, Eilat, D, Wilson, I.A.
Deposit date:2013-08-08
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal structure determination of anti-DNA Fab A52.
Proteins, 82, 2014
4QQW
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BU of 4qqw by Molmil
Crystal structure of T. fusca Cas3
Descriptor: CRISPR-associated helicase, Cas3 family, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
Authors:Ke, A, Huo, Y, Nam, K.H.
Deposit date:2014-06-30
Release date:2014-08-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.664 Å)
Cite:Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
2ZXR
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BU of 2zxr by Molmil
Crystal structure of RecJ in complex with Mg2+ from Thermus thermophilus HB8
Descriptor: MAGNESIUM ION, Single-stranded DNA specific exonuclease RecJ
Authors:Wakamatsu, T, Kitamura, Y, Nakagawa, N, Masui, R, Kuramitsu, S.
Deposit date:2009-01-05
Release date:2010-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of RecJ exonuclease defines its specificity for single-stranded DNA
J.Biol.Chem., 285, 2010
2H8C
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BU of 2h8c by Molmil
Structure of RusA D70N in complex with DNA
Descriptor: 5'-D(*CP*CP*GP*GP*TP*AP*CP*CP*GP*GP*T)-3', Crossover junction endodeoxyribonuclease rusA
Authors:Macmaster, R.A.
Deposit date:2006-06-07
Release date:2007-04-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:RusA Holliday junction resolvase: DNA complex structure--insights into selectivity and specificity.
Nucleic Acids Res., 34, 2006
4FW1
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BU of 4fw1 by Molmil
Crystal structure of two-domain RSV INTEGRASE covalently linked with DNA
Descriptor: Integrase
Authors:Shi, K, Aihara, H.
Deposit date:2012-06-29
Release date:2013-05-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:A possible role for the asymmetric C-terminal domain dimer of Rous sarcoma virus integrase in viral DNA binding.
Plos One, 8, 2013
1HX4
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BU of 1hx4 by Molmil
MOLECULAR TOPOLOGY OF POLYCYCLIC AROMATIC CARCINOGENS DETERMINES DNA ADDUCT CONFORMATION: A LINK TO TUMORIGENIC ACTIVITY
Descriptor: (1R)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL, 5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3'
Authors:Patel, D.J, Lin, C.H, Geacintov, N.E, Broyde, S, Huang, X, Kolbanovskii, A, Hingerty, B.E, Amin, S.
Deposit date:2001-01-11
Release date:2001-03-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity.
J.Mol.Biol., 306, 2001
1EUG
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BU of 1eug by Molmil
CRYSTAL STRUCTURE OF ESCHERICHIA COLI URACIL DNA GLYCOSYLASE AND ITS COMPLEXES WITH URACIL AND GLYCEROL: STRUCTURE AND GLYCOSYLASE MECHANISM REVISITED
Descriptor: PROTEIN (GLYCOSYLASE)
Authors:Xiao, G, Tordova, M, Jagadeesh, J, Drohat, A.C, Stivers, J.T, Gilliland, G.L.
Deposit date:1998-10-12
Release date:1999-10-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: structure and glycosylase mechanism revisited.
Proteins, 35, 1999
1EKI
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BU of 1eki by Molmil
AVERAGE SOLUTION STRUCTURE OF D(TTGGCCAA)2 BOUND TO CHROMOMYCIN-A3 AND COBALT
Descriptor: (1S)-5-deoxy-1-O-methyl-1-C-[(2R,3S)-3,5,7,10-tetrahydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl]-D-xylulose, 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose-(1-3)-4-O-acetyl-2,6-dideoxy-beta-D-galactopyranose, 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose-(1-3)-beta-D-Olivopyranose-(1-3)-beta-D-Olivopyranose, ...
Authors:Gochin, M.
Deposit date:2000-03-08
Release date:2000-03-20
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:A high-resolution structure of a DNA-chromomycin-Co(II) complex determined from pseudocontact shifts in nuclear magnetic resonance.
Structure Fold.Des., 8, 2000
1ADN
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BU of 1adn by Molmil
SOLUTION STRUCTURE OF THE DNA METHYLPHOSPHOTRIESTER REPAIR DOMAIN OF ESCHERICHIA COLI ADA
Descriptor: N-ADA 10, ZINC ION
Authors:Myers, L.C, Verdine, G.L, Wagner, G.
Deposit date:1993-09-30
Release date:1994-01-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the DNA methyl phosphotriester repair domain of Escherichia coli Ada.
Biochemistry, 32, 1993
3F73
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BU of 3f73 by Molmil
Alignment of guide-target seed duplex within an argonaute silencing complex
Descriptor: ARGONAUTE, DNA (5'-D(P*DTP*DGP*DAP*DGP*DGP*DTP*DAP*DGP*DTP*DAP*DGP*DGP*DTP*DTP*DGP*DTP*DA*DTP*DAP*DGP*DT)-3'), MAGNESIUM ION, ...
Authors:Wang, Y, Li, H, Sheng, G, Juranek, S, Tuschl, T, Patel, D.J.
Deposit date:2008-11-07
Release date:2008-12-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex.
Nature, 456, 2008
7DW5
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BU of 7dw5 by Molmil
Crystal structure of DUX4 HD1-HD2 domain complexed with ERG sites
Descriptor: BROMIDE ION, DNA (5'-D(P*CP*GP*AP*CP*TP*TP*GP*AP*TP*GP*AP*GP*AP*TP*TP*AP*GP*AP*CP*TP*G)-3'), Double homeobox protein 4-like protein 2
Authors:Zhang, H, Cheng, N, Li, Z, Zhang, W, Dong, X, Huang, J, Meng, G.
Deposit date:2021-01-15
Release date:2021-11-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:DNA crosslinking and recombination-activating genes 1/2 (RAG1/2) are required for oncogenic splicing in acute lymphoblastic leukemia.
Cancer Commun (Lond), 41, 2021
3NP6
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The crystal structure of Berberine bound to DNA d(CGTACG)
Descriptor: 5'-D(*CP*GP*TP*AP*CP*G)-3', BERBERINE, CALCIUM ION
Authors:Ferraroni, M, Bazzicalupi, C, Gratteri, P, Bilia, A.R.
Deposit date:2010-06-28
Release date:2011-05-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-Ray diffraction analyses of the natural isoquinoline alkaloids Berberine and Sanguinarine complexed with double helix DNA d(CGTACG)
Chem.Commun.(Camb.), 47, 2011
6SCE
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BU of 6sce by Molmil
Structure of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate
Descriptor: Uncharacterized protein, cyclic oligoadenylate
Authors:McMahon, S.A, Zhu, W, Graham, S, White, M.F, Gloster, T.M.
Deposit date:2019-07-24
Release date:2020-02-19
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structure and mechanism of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate.
Nat Commun, 11, 2020

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