PDB: 1466 resultsInfo pagesStatus searchChemie searchBIRD

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6R7F	Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome Descriptor: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... Authors: Faull, S.V, Lau, A.M.C, Martens, C, Ahdash, Z, Yebenes, H, Schmidt, C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. Deposit date: 2019-03-28 Release date: 2019-08-28 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (8.2 Å) Cite: Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
6R7H	Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome Descriptor: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... Authors: Faull, S.V, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. Deposit date: 2019-03-28 Release date: 2019-08-28 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (8.8 Å) Cite: Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
6R7I	Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome Descriptor: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... Authors: Faull, S.F, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. Deposit date: 2019-03-28 Release date: 2019-08-28 Last modified: 2019-09-04 Method: ELECTRON MICROSCOPY (5.9 Å) Cite: Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
6R6P	Structure of XBP1u-paused ribosome nascent chain complex (rotated state) Descriptor: 18S rRNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... Authors: Shanmuganathan, V, Cheng, J, Berninghausen, O, Beckmann, R. Deposit date: 2019-03-27 Release date: 2019-07-10 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural and mutational analysis of the ribosome-arresting human XBP1u. Elife, 8, 2019
6R6G	Structure of XBP1u-paused ribosome nascent chain complex with SRP. Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... Authors: Shanmuganathan, V, Cheng, J, Braunger, K, Berninghausen, O, Beatrix, B, Beckmann, R. Deposit date: 2019-03-27 Release date: 2019-07-10 Last modified: 2019-10-30 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural and mutational analysis of the ribosome-arresting human XBP1u. Elife, 8, 2019
6R6H	Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome Descriptor: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... Authors: Morris, E.P, Faull, S.V, Lau, A.M.C, Politis, A, Beuron, F, Cronin, N. Deposit date: 2019-03-27 Release date: 2019-08-28 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (8.4 Å) Cite: Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
6R5Q	Structure of XBP1u-paused ribosome nascent chain complex (post-state) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... Authors: Shanmuganathan, V, Cheng, J, Berninghausen, O, Beckmann, R. Deposit date: 2019-03-25 Release date: 2019-07-10 Last modified: 2019-10-30 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural and mutational analysis of the ribosome-arresting human XBP1u. Elife, 8, 2019
6OAM	Crystal Structure of ChlaDUB2 DUB domain Descriptor: Deubiquitinase and deneddylase Dub2, Ubiquitin Authors: Hausman, J.M, Das, C. Deposit date: 2019-03-17 Release date: 2020-04-22 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.503 Å) Cite: The Two Deubiquitinating Enzymes fromChlamydia trachomatisHave Distinct Ubiquitin Recognition Properties. Biochemistry, 59, 2020
6OA9	Cdc48-Npl4 complex processing poly-ubiquitinated substrate in the presence of ATP Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ... Authors: Twomey, E.C, Ji, Z, Wales, T.E, Bodnar, N.O, Engen, J.R, Rapoport, T.A. Deposit date: 2019-03-15 Release date: 2019-07-03 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding. Science, 365, 2019
6OAA	Cdc48-Npl4 complex processing poly-ubiquitinated substrate in the presence of ADP-BeFx, state 1 Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ... Authors: Twomey, E.C, Ji, Z, Wales, T.E, Bodnar, N.O, Engen, J.R, Rapoport, T.A. Deposit date: 2019-03-15 Release date: 2019-07-03 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding. Science, 365, 2019
6O96	Dot1L bound to the H2BK120 Ubiquitinated nucleosome Descriptor: DNA (146-MER), Histone H2A, Histone H2B 1.1, ... Authors: Valencia-Sanchez, M.I, De Ioannes, P.E, Miao, W, Vasilyev, N, Chen, R, Nudler, E, Armache, J.-P, Armache, K.-J. Deposit date: 2019-03-13 Release date: 2019-04-24 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination. Mol.Cell, 74, 2019
6O83	S. pombe ubiquitin E1~ubiquitin-AMP tetrahedral intermediate mimic Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-{[(3-aminopropyl)sulfonyl]amino}-5'-deoxyadenosine, ... Authors: Hann, Z.S, Lima, C.D. Deposit date: 2019-03-08 Release date: 2019-06-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.153 Å) Cite: Structural basis for adenylation and thioester bond formation in the ubiquitin E1. Proc.Natl.Acad.Sci.USA, 116, 2019
6O82	S. pombe ubiquitin E1 complex with a ubiquitin-AMP mimic Descriptor: 1,2-ETHANEDIOL, 5'-deoxy-5'-(sulfamoylamino)adenosine, MAGNESIUM ION, ... Authors: Olsen, S.K, Lima, C.D. Deposit date: 2019-03-08 Release date: 2019-06-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.604 Å) Cite: Structural basis for adenylation and thioester bond formation in the ubiquitin E1. Proc.Natl.Acad.Sci.USA, 116, 2019
6JMA	cryo-EM structure of DOT1L bound to H2B ubiquitinated nucleosome Descriptor: DNA I&J, Histone H2A, Histone H2B 1.1, ... Authors: Jang, S, Song, J.J. Deposit date: 2019-03-07 Release date: 2019-05-15 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (6.8 Å) Cite: Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase. Genes Dev., 33, 2019
6QX9	Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, AdML pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Charenton, C, Wilkinson, M.E, Nagai, K. Deposit date: 2019-03-07 Release date: 2019-04-17 Last modified: 2020-10-07 Method: ELECTRON MICROSCOPY (3.28 Å) Cite: Mechanism of 5' splice site transfer for human spliceosome activation. Science, 364, 2019
6JKY	Crystal structure of MvcA-UBE2N-Ub complex from Legionella pneumophila Descriptor: MvcA, Ub, Ubiquitin-conjugating enzyme E2 N Authors: Ouyang, S.Y, Guan, H. Deposit date: 2019-03-03 Release date: 2019-12-18 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.454 Å) Cite: Legionella pneumophila regulates the activity of UBE2N by deamidase-mediated deubiquitination. Embo J., 39, 2020
6JL3	Crystal Structure of the UBL domain of Plasmodium Falciparum Dsk2 Descriptor: Ubiquitin domain-containing protein DSK2,putative Authors: Gupta, I, Khan, S. Deposit date: 2019-03-03 Release date: 2020-02-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.303 Å) Cite: The recognition of proteasomal receptors by Plasmodium falciparum DSK2. Mol.Biochem.Parasitol., 236, 2020
6O49	CRYSTAL STRUCTURE OF SMT FUSION PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FROM BURKHOLDERIA PSEUDOMALLEI COMPLEXED WITH SF339 Descriptor: (2~{S})-~{N}-[3-oxidanylidene-3-[(3,4,5-trimethoxyphenyl)amino]propyl]-1-(phenylmethyl)sulfonyl-piperidine-2-carboxamide, 1,2-ETHANEDIOL, CALCIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2019-02-28 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.85 Å) Cite: CRYSTAL STRUCTURE OF SMT FUSION PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FROM BURKHOLDERIA PSEUDOMALLEI COMPLEXED WITH SF339 to be published
6O4A	CRYSTAL STRUCTURE OF SMT FUSION PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FROM BURKHOLDERIA PSEUDOMALLEI COMPLEXED WITH SF355 Descriptor: 2-(pyridin-3-ylcarbonylamino)ethyl (2~{S})-1-(phenylmethyl)sulfonylpiperidine-2-carboxylate, CALCIUM ION, Ubiquitin-like protein SMT3,Peptidyl-prolyl cis-trans isomerase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2019-02-28 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.1 Å) Cite: CRYSTAL STRUCTURE OF SMT FUSION PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FROM BURKHOLDERIA PSEUDOMALLEI COMPLEXED WITH SF355 to be published
6QTZ	Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Kargas, V, Warren, A.J. Deposit date: 2019-02-26 Release date: 2019-06-26 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Mechanism of completion of peptidyltransferase centre assembly in eukaryotes. Elife, 8, 2019
6QT0	Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Kargas, V, Warren, A.J. Deposit date: 2019-02-22 Release date: 2019-06-26 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Mechanism of completion of peptidyltransferase centre assembly in eukaryotes. Elife, 8, 2019
6JH1	Crystal structure of bISG15/NS1B complex Descriptor: Non-structural protein 1, Ubiquitin-like protein ISG15 Authors: Jiang, Y.N, Wang, X.W. Deposit date: 2019-02-16 Release date: 2019-10-16 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal structure of bISG15/NS1B complex To Be Published
6NZO	Set2 bound to nucleosome Descriptor: DNA (149-MER), Histone H2B 1.1, Histone H3, ... Authors: Halic, M, Bilokapic, S. Deposit date: 2019-02-14 Release date: 2019-08-28 Last modified: 2019-09-04 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Nucleosome and ubiquitin position Set2 to methylate H3K36. Nat Commun, 10, 2019
6NYA	Crystal Structure of ubiquitin E1 (Uba1) in complex with Ubc3 (Cdc34) and ubiquitin Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Olsen, S.K, Williams, K.M, Atkison, J.H. Deposit date: 2019-02-11 Release date: 2019-08-07 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.065 Å) Cite: Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34. Nat Commun, 10, 2019
6NYO	Crystal structure of a human Cdc34-ubiquitin thioester mimetic Descriptor: 1,2-ETHANEDIOL, 4,5-dideoxy-5-(3',5'-dichlorobiphenyl-4-yl)-4-[(methoxyacetyl)amino]-L-arabinonic acid, PHOSPHATE ION, ... Authors: Olsen, S.K, Williams, K.M, Atkison, J.H. Deposit date: 2019-02-11 Release date: 2019-08-07 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.502 Å) Cite: Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34. Nat Commun, 10, 2019

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