6NYA

Crystal Structure of ubiquitin E1 (Uba1) in complex with Ubc3 (Cdc34) and ubiquitin

Summary for 6NYA

Entry DOI	10.2210/pdb6nya/pdb
Descriptor	Ubiquitin-activating enzyme E1 1, Ubiquitin, Ubiquitin-conjugating enzyme E2-34 kDa, ... (8 entities in total)
Functional Keywords	conformational change, thioester, adenylation, thioester transfer, transthioesterification, atp-binding, ubiquitin e2-binding, ubiquitination, ligase, ligase-transferase complex, ligase/transferase
Biological source	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More
Total number of polymer chains	6
Total formula weight	295712.21
Authors	Olsen, S.K.,Williams, K.M.,Atkison, J.H. (deposition date: 2019-02-11, release date: 2019-08-07, Last modification date: 2023-10-11)
Primary citation	Williams, K.M.,Qie, S.,Atkison, J.H.,Salazar-Arango, S.,Alan Diehl, J.,Olsen, S.K. Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34. Nat Commun, 10:3296-3296, 2019 Cited by PubMed: 31341161 DOI: 10.1038/s41467-019-11061-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.065 Å)

Structure validation