6NYO

Crystal structure of a human Cdc34-ubiquitin thioester mimetic

Summary for 6NYO

Entry DOI	10.2210/pdb6nyo/pdb
Related	6NYA 6NYD
Descriptor	Ubiquitin-conjugating enzyme E2 R2, Ubiquitin, 4,5-dideoxy-5-(3',5'-dichlorobiphenyl-4-yl)-4-[(methoxyacetyl)amino]-L-arabinonic acid, ... (6 entities in total)
Functional Keywords	conformational change, thioester, adenylation, thioester transfer, transthioesterification, atp-binding, ubiquitin e2-binding, ubiquitination, ligase, ligase-transferase complex, ligase/transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	34629.80
Authors	Olsen, S.K.,Williams, K.M.,Atkison, J.H. (deposition date: 2019-02-11, release date: 2019-08-07, Last modification date: 2023-10-11)
Primary citation	Williams, K.M.,Qie, S.,Atkison, J.H.,Salazar-Arango, S.,Alan Diehl, J.,Olsen, S.K. Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34. Nat Commun, 10:3296-3296, 2019 Cited by PubMed: 31341161 DOI: 10.1038/s41467-019-11061-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.502 Å)

Structure validation