6NYO
Crystal structure of a human Cdc34-ubiquitin thioester mimetic
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Ubiquitin-conjugating enzyme E2 R2 | polymer | 204 | 23166.2 | 1 | UniProt (Q712K3) Pfam (PF00179) In PDB | Homo sapiens (Human) | E2 ubiquitin-conjugating enzyme R2,Ubiquitin carrier protein R2,Ubiquitin-conjugating enzyme E2-CDC34B,Ubiquitin-protein ligase R2 |
2 | E | Ubiquitin | polymer | 96 | 10740.1 | 1 | Pfam (PF00240) UniProt (by SIFTS) (P0CH08) In PDB | Schizosaccharomyces pombe (fission yeast) | |
3 | A | 4,5-dideoxy-5-(3',5'-dichlorobiphenyl-4-yl)-4-[(methoxyacetyl)amino]-L-arabinonic acid | non-polymer | 442.3 | 1 | Chemie (U94) | |||
4 | A, E | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
5 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
6 | water | water | 18.0 | 319 | Chemie (HOH) |
Sequence modifications
A: 1 - 202 (UniProt: Q712K3)
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ala 0 | - | expression tag |
Lys 93 | Cys 93 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 33906.3 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 723.5 | |
All* | Total formula weight | 34629.8 |