PDB: 54296 resultsInfo pagesStatus searchChemie searchBIRD

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6SIH	Structure of bacterial flagellar capping protein FliD Descriptor: Flagellar hook-associated protein 2 Authors: Al-Otaibi, N.S, Farrell, D, DiMaio, F, Bergeron, J.R.C. Deposit date: 2019-08-09 Release date: 2020-05-27 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: The cryo-EM structure of the bacterial flagellum cap complex suggests a molecular mechanism for filament elongation. Nat Commun, 11, 2020
8JW0	PSI-AcpPCI supercomplex from Amphidinium carterae Descriptor: (3S,3'R,5R,6S,7cis)-7',8'-didehydro-5,6-dihydro-5,6-epoxy-beta,beta-carotene-3,3'-diol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... Authors: Li, Z.H, Li, X.Y, Wang, W.D. Deposit date: 2023-06-28 Release date: 2024-02-28 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structures and organizations of PSI-AcpPCI supercomplexes from red tidal and coral symbiotic photosynthetic dinoflagellates. Proc.Natl.Acad.Sci.USA, 121, 2024
4YXS	CAMP-DEPENDENT PROTEIN KINASE PKA CATALYTIC SUBUNIT WITH PKI-5-24 Descriptor: N-BENZYL-9H-PURIN-6-AMINE, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha Authors: Schiffer, A, Wendt, K.U. Deposit date: 2015-03-23 Release date: 2015-05-20 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.11 Å) Cite: A combination of spin diffusion methods for the determination of protein-ligand complex structural ensembles. Angew.Chem.Int.Ed.Engl., 54, 2015
2K33	Solution structure of an N-glycosylated protein using in vitro glycosylation Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-4)-[beta-D-glucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-2,4-bisacetamido-2,4,6-trideoxy-beta-D-glucopyranose, AcrA Authors: Slynko, V, Schubert, M, Numao, S, Kowarik, M, Aebi, M, Allain, F.H.-T. Deposit date: 2008-04-18 Release date: 2009-02-03 Last modified: 2024-11-06 Method: SOLUTION NMR Cite: NMR structure determination of a segmentally labeled glycoprotein using in vitro glycosylation. J.Am.Chem.Soc., 131, 2009
3TNP	Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit Authors: Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S. Deposit date: 2011-09-01 Release date: 2012-02-01 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure and allostery of the PKA RIIbeta tetrameric holoenzyme Science, 335, 2012
3DND	cAMP-dependent protein kinase PKA catalytic subunit with PKI-5-24 Descriptor: 5-benzyl-1,3-thiazol-2-amine, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha Authors: Schiffer, A, Wendt, K.U. Deposit date: 2008-07-02 Release date: 2009-06-23 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Crystallography-independent determination of ligand binding modes Angew.Chem.Int.Ed.Engl., 47, 2008
3DNE	cAMP-dependent protein kinase PKA catalytic subunit with PKI-5-24 Descriptor: 3-pyridin-4-yl-1H-indazole, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha Authors: Schiffer, A, Wendt, K.U. Deposit date: 2008-07-02 Release date: 2009-06-23 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystallography-independent determination of ligand binding modes Angew.Chem.Int.Ed.Engl., 47, 2008
3BFU	Structure of the ligand-binding core of GluR2 in complex with the agonist (R)-TDPA at 1.95 A resolution Descriptor: (2R)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propanoic acid, Glutamate receptor 2 Authors: Beich-Frandsen, M, Mirza, O, Vestergaard, B, Gajhede, M, Kastrup, J.S. Deposit date: 2007-11-23 Release date: 2008-10-14 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency. J.Med.Chem., 51, 2008
4O10	Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase Descriptor: 1,2-ETHANEDIOL, N-{4-[(3,5-difluorophenyl)sulfonyl]benzyl}indolizine-7-carboxamide, Nicotinamide phosphoribosyltransferase, ... Authors: Oh, A, Wang, W. Deposit date: 2013-12-14 Release date: 2014-06-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase. Chembiochem, 15, 2014
3BFT	Structure of the ligand-binding core of GluR2 in complex with the agonist (S)-TDPA at 2.25 A resolution Descriptor: (2S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propanoic acid, CACODYLATE ION, CHLORIDE ION, ... Authors: Beich-Frandsen, M, Mirza, O, Vestergaard, B, Gajhede, M, Kastrup, J.S. Deposit date: 2007-11-23 Release date: 2008-10-28 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency. J.Med.Chem., 51, 2008
4O12	Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase Descriptor: 2-[6-(4-chlorophenoxy)hexyl]-1-cyano-3-pyridin-4-ylguanidine, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION Authors: Oh, A, Wang, W. Deposit date: 2013-12-14 Release date: 2014-06-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.498 Å) Cite: Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase. Chembiochem, 15, 2014
4O0Z	Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase Descriptor: N-{4-[(3,5-difluorophenyl)sulfonyl]benzyl}indolizine-6-carboxamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION Authors: Oh, A, Wang, W. Deposit date: 2013-12-14 Release date: 2014-06-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.049 Å) Cite: Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase. Chembiochem, 15, 2014
2GFC	cAMP-dependent protein kinase PKA catalytic subunit with PKI-5-24 Descriptor: N-OCTANE, cAMP-dependent protein kinase inhibitor alpha, cAMP-dependent protein kinase, ... Authors: Bonn, S, Herrero, S, Breitenlechner, C.B, Engh, R.A, Gassel, M, Bossemeyer, D. Deposit date: 2006-03-21 Release date: 2006-05-23 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Structural Analysis of Protein Kinase A Mutants with Rho-kinase Inhibitor Specificity. J.Biol.Chem., 281, 2006
4XUX	Structure of ampC bound to RPX-7009 at 1.75 A Descriptor: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, Beta-lactamase, ... Authors: Clifton, M.C, Abendroth, J. Deposit date: 2015-01-26 Release date: 2015-04-01 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Discovery of a Cyclic Boronic Acid beta-Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases. J.Med.Chem., 58, 2015
3CP4	CRYSTAL STRUCTURE OF THE CYTOCHROME P450-CAM ACTIVE SITE MUTANT THR252ALA Descriptor: ADAMANTANE, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE Authors: Raag, R, Poulos, T.L. Deposit date: 1991-06-04 Release date: 1993-01-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of the cytochrome P-450CAM active site mutant Thr252Ala. Biochemistry, 30, 1991
4E3M	Crystal structure of AmpC beta-lactamase in complex with a 2-chloro-4-tetrazolyl benzene sulfonamide boronic acid inhibitor Descriptor: Beta-lactamase, PHOSPHATE ION, [({[2-chloro-4-(1H-tetrazol-5-yl)phenyl]sulfonyl}amino)methyl]boronic acid Authors: Eidam, O, Shoichet, B.K. Deposit date: 2012-03-09 Release date: 2012-09-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.44 Å) Cite: Fragment-guided design of subnanomolar beta-lactamase inhibitors active in vivo. Proc.Natl.Acad.Sci.USA, 109, 2012
4E3I	Crystal structure of AmpC beta-lactamase in complex with a designed 3-carboxyl benzyl sulfonamide boronic acid inhibitor Descriptor: 3-({[(dihydroxyboranyl)methyl]sulfamoyl}methyl)benzoic acid, Beta-lactamase, PHOSPHATE ION Authors: Eidam, O, Shoichet, B.K. Deposit date: 2012-03-09 Release date: 2012-09-26 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Fragment-guided design of subnanomolar beta-lactamase inhibitors active in vivo. Proc.Natl.Acad.Sci.USA, 109, 2012
4E3O	Crystal structure of AmpC beta-lactamase in complex with a small chloromethyl sulfonamide boronic acid inhibitor Descriptor: ({[(chloromethyl)sulfonyl]amino}methyl)boronic acid, Beta-lactamase, PHOSPHATE ION Authors: Eidam, O, Shoichet, B.K. Deposit date: 2012-03-09 Release date: 2012-09-26 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Fragment-guided design of subnanomolar beta-lactamase inhibitors active in vivo. Proc.Natl.Acad.Sci.USA, 109, 2012
2MD1	Fragment based approach and binding behavior of LFampinB with Lipopolysaccharide:biophysical aspects Descriptor: Lactotransferrin Authors: Bhunia, A, Chatterjee, S, Ghosh, A, Jana, J. Deposit date: 2013-08-29 Release date: 2013-09-25 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Sequence context induced antimicrobial activity: insight into lipopolysaccharide permeabilization. Mol Biosyst, 10, 2014
4E3L	Crystal structure of AmpC beta-lactamase in complex with a 3-chloro-4-tetrazolyl benzene sulfonamide boronic acid inhibitor Descriptor: Beta-lactamase, PHOSPHATE ION, [({[3-chloro-4-(1H-tetrazol-5-yl)phenyl]sulfonyl}amino)methyl]boronic acid Authors: Eidam, O, Shoichet, B.K. Deposit date: 2012-03-09 Release date: 2012-09-26 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Fragment-guided design of subnanomolar beta-lactamase inhibitors active in vivo. Proc.Natl.Acad.Sci.USA, 109, 2012
4E3K	Crystal structure of AmpC beta-lactamase in complex with a designed 4-tetrazolyl pyridine sulfonamide boronic acid inhibitor Descriptor: Beta-lactamase, PHOSPHATE ION, [({[6-(1H-tetrazol-5-yl)pyridin-3-yl]sulfonyl}amino)methyl]boronic acid Authors: Eidam, O, Shoichet, B.K. Deposit date: 2012-03-09 Release date: 2012-09-26 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.4299 Å) Cite: Fragment-guided design of subnanomolar beta-lactamase inhibitors active in vivo. Proc.Natl.Acad.Sci.USA, 109, 2012
4E3N	Crystal structure of AmpC beta-lactamase in complex with a 2-trifluoromethyl-4-tetrazolyl benzene sulfonamide boronic acid inhibitor Descriptor: Beta-lactamase, PHOSPHATE ION, [({[4-(1H-tetrazol-5-yl)-2-(trifluoromethyl)phenyl]sulfonyl}amino)methyl]boronic acid Authors: Eidam, O, Shoichet, B.K. Deposit date: 2012-03-09 Release date: 2012-09-26 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.49 Å) Cite: Fragment-guided design of subnanomolar beta-lactamase inhibitors active in vivo. Proc.Natl.Acad.Sci.USA, 109, 2012
2ZAW	Crystal Structure of Ferric Cytochrome P450cam Reconstituted with 6-Methyl-6-depropionated Hemin Descriptor: 6-METHY-6-DEPROPIONATEHEMIN, CAMPHOR, CHLORIDE ION, ... Authors: Harada, K, Sakurai, K, Shimada, H, Tsukihara, T, Hayashi, T. Deposit date: 2007-10-11 Release date: 2008-01-01 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Evaluation of the functional role of the heme-6-propionate side chain in cytochrome P450cam J.Am.Chem.Soc., 130, 2008
1XX2	Refinement of P99 beta-lactamase from Enterobacter cloacae Descriptor: Beta-lactamase Authors: Knox, J.R, Sun, T. Deposit date: 2004-11-03 Release date: 2004-11-23 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Crystallographic structure of a phosphonate derivative of the Enterobacter cloacae P99 cephalosporinase: mechanistic interpretation of a beta-lactamase transition-state analog. Biochemistry, 33, 1994
2MD3	Fragment based approach and binding behavior of LFampinB with Lipopolysaccharide:biophysical aspects Descriptor: Lactotransferrin Authors: Bhunia, A, Chatterjee, S, Ghosh, A, Jana, J. Deposit date: 2013-08-29 Release date: 2013-09-25 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Sequence context induced antimicrobial activity: insight into lipopolysaccharide permeabilization. Mol Biosyst, 10, 2014

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