4YXS

CAMP-DEPENDENT PROTEIN KINASE PKA CATALYTIC SUBUNIT WITH PKI-5-24

Summary for 4YXS

Related4EXF
DescriptorcAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, N-BENZYL-9H-PURIN-6-AMINE, ... (4 entities in total)
Functional Keywordsatp-binding, phosphoprotein, serine/threonine-protein kinase, transferase, camp, protein kinase inhibitor, transferase-in complex, transferase-inhibitor complex, transferase/inhibitor
Biological sourceBos taurus (Bovine)
More
Cellular locationCytoplasm  P00517
Total number of polymer chains2
Total molecular weight43159.06
Authors
Schiffer, A.,Wendt, K.U. (deposition date: 2015-03-23, release date: 2015-05-20, Last modification date: 2015-06-03)
Primary citation
Pilger, J.,Mazur, A.,Monecke, P.,Schreuder, H.,Elshorst, B.,Bartoschek, S.,Langer, T.,Schiffer, A.,Krimm, I.,Wegstroth, M.,Lee, D.,Hessler, G.,Wendt, K.U.,Becker, S.,Griesinger, C.
A combination of spin diffusion methods for the determination of protein-ligand complex structural ensembles.
Angew.Chem.Int.Ed.Engl., 54:6511-6515, 2015
PubMed: 25877959 (PDB entries with the same primary citation)
DOI: 10.1002/anie.201500671
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.11 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.237305.8%1.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution