8BG8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bg8 by Molmil](/molmil-images/mine/8bg8) | SARS-CoV-2 S protein in complex with pT1696 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, pT1696 Fab heavy chain, ... | Authors: | Hansen, G, Benecke, T, Vollmer, B, Gruenewald, K, Krey, T. | Deposit date: | 2022-10-27 | Release date: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.64 Å) | Cite: | Activity of broadly neutralizing antibodies against sarbecoviruses: a trade-off between SARS-CoV-2 variants and distant coronaviruses? To be published
|
|
8C7H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c7h by Molmil](/molmil-images/mine/8c7h) | Cryo-EM Map of the latTGF-beta 28G11 Fab complex | Descriptor: | 28G11 Fab heavy chain, 28G11 Fab light chain, Transforming growth factor beta activator LRRC32, ... | Authors: | Ebenhoch, R, Nar, H. | Deposit date: | 2023-01-16 | Release date: | 2023-03-01 | Last modified: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Anti-GARP Antibodies Inhibit Release of TGF-beta by Regulatory T Cells via Different Modes of Action, but Do Not Influence Their Function In Vitro. Immunohorizons, 7, 2023
|
|
8C9N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c9n by Molmil](/molmil-images/mine/8c9n) | MiniCoV-ADDomer, a SARS-CoV-2 epitope presenting viral like particle | Descriptor: | Penton protein | Authors: | Bufton, J.C, Capin, J, Boruku, U, Garzoni, F, Schaffitzel, C, Berger, I. | Deposit date: | 2023-01-23 | Release date: | 2023-12-06 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (2.36 Å) | Cite: | In vitro generated antibodies guide thermostable ADDomer nanoparticle design for nasal vaccination and passive immunization against SARS-CoV-2. Antib Ther, 6, 2023
|
|
5LDY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ldy by Molmil](/molmil-images/mine/5ldy) | Structure of Yersinia pseudotuberculosis InvD | Descriptor: | Ig domain protein group 1 domain protein, PHOSPHATE ION | Authors: | Sadana, P, Scrima, A. | Deposit date: | 2016-06-28 | Release date: | 2017-06-14 | Last modified: | 2020-06-17 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The invasin D protein from Yersinia pseudotuberculosis selectively binds the Fab region of host antibodies and affects colonization of the intestine J.Biol.Chem., 2018
|
|
6DE7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6de7 by Molmil](/molmil-images/mine/6de7) | |
8OG0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8og0 by Molmil](/molmil-images/mine/8og0) | |
5DR5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dr5 by Molmil](/molmil-images/mine/5dr5) | Crystal structure of the sclerostin-neutralizing Fab AbD09097 | Descriptor: | AbD09097 Fab heavy chain, AbD09097 Fab light chain | Authors: | Mueller, T.D, Boschert, V, Weidauer, S.E, Muth, E.M, Knappik, A, Frisch, C. | Deposit date: | 2015-09-15 | Release date: | 2016-08-31 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Generation and Affinity Maturation of Neutralizing Anti-Sclerostin Antibodies to be published
|
|
1F9Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1f9q by Molmil](/molmil-images/mine/1f9q) | CRYSTAL STRUCTURE OF PLATELET FACTOR 4 | Descriptor: | PLATELET FACTOR 4 | Authors: | Yang, J, Doyle, M, Faulk, T, Visentin, G, Aster, R, Edwards, B. | Deposit date: | 2000-07-11 | Release date: | 2003-08-26 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure Comparison of Two Platelet Factor 4 Mutants with the Wild-Type Reveals the Epitopes for the Heparin-Induced Thrombocytopenia Antibodies To be Published
|
|
1F9R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1f9r by Molmil](/molmil-images/mine/1f9r) | CRYSTAL STRUCTURE OF PLATELET FACTOR 4 MUTANT 1 | Descriptor: | PLATELET FACTOR 4 | Authors: | Yang, J, Doyle, M, Faulk, T, Visentin, G, Aster, R, Edwards, B. | Deposit date: | 2000-07-11 | Release date: | 2003-08-26 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure Comparison of Two Platelet Factor 4 Mutants with the Wild-type Reveals the Epitopes for the Heparin-induced Thrombocytopenia Antibodies To be Published
|
|
1F9S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1f9s by Molmil](/molmil-images/mine/1f9s) | CRYSTAL STRUCTURE OF PLATELET FACTOR 4 MUTANT 2 | Descriptor: | PLATELET FACTOR 4 | Authors: | Yang, J, Doyle, M, Faulk, T, Visentin, G, Aster, R, Edwards, B. | Deposit date: | 2000-07-11 | Release date: | 2003-08-26 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Structure Comparison of Two Platelet Factor 4 Mutants with the Wild-type Reveals the Epitopes for the Heparin-induced Thrombocytopenia Antibodies To be Published
|
|
1FUJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1fuj by Molmil](/molmil-images/mine/1fuj) | PR3 (MYELOBLASTIN) | Descriptor: | PR3, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Fujinaga, M, Chernaia, M.M, Halenbeck, R, Koths, K, James, M.N.G. | Deposit date: | 1996-01-25 | Release date: | 1996-07-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The crystal structure of PR3, a neutrophil serine proteinase antigen of Wegener's granulomatosis antibodies. J.Mol.Biol., 261, 1996
|
|
6CEX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6cex by Molmil](/molmil-images/mine/6cex) | |
5YS6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ys6 by Molmil](/molmil-images/mine/5ys6) | |
6O89
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o89 by Molmil](/molmil-images/mine/6o89) | Anti-CD28xCD3 CODV Fab | Descriptor: | Anti-CD28xCD3 CODV-Fab Heavy chain, Anti-CD28xCD3 CODV-Fab Light chain | Authors: | Lord, D.M, Wei, R.R. | Deposit date: | 2019-03-09 | Release date: | 2019-11-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation Nat Cancer, 1, 2020
|
|
4O9H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o9h by Molmil](/molmil-images/mine/4o9h) | Structure of Interleukin-6 in complex with a Camelid Fab fragment | Descriptor: | Heavy Chain of the Camelid Fab fragment 61H7, Interleukin-6, Light Chain of the Camelid Fab fragment 61H7 | Authors: | Klarenbeek, A, Blanchetot, C, Schragel, G, Sadi, A.S, Ongenae, N, Hemrika, W, Wijdenes, J, Spinelli, S, Desmyter, A, Cambillau, C, Hultberg, A, Kretz-rommel, A, Dreier, T, De haard, H.J.W, Roovers, R.C. | Deposit date: | 2014-01-02 | Release date: | 2015-04-15 | Last modified: | 2015-04-29 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Combining residues of naturally-occurring Camelid somatic affinity variants yields ultra-potent human therapeutic IL-6 antibodies To be Published
|
|
8TQI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8tqi by Molmil](/molmil-images/mine/8tqi) | |
8TQK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8tqk by Molmil](/molmil-images/mine/8tqk) | |
7JR7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jr7 by Molmil](/molmil-images/mine/7jr7) | Cryo-EM structure of ABCG5/G8 in complex with Fab 2E10 and 11F4 | Descriptor: | ATP-binding cassette sub-family G member 5, ATP-binding cassette sub-family G member 8, Fab 11F4 heavy chain, ... | Authors: | Huang, C.S, Yu, X, Min, X, Wang, Z, Zhang, H. | Deposit date: | 2020-08-11 | Release date: | 2021-04-07 | Last modified: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structure of ABCG5/G8 in complex with modulating antibodies Commun Biol, 4, 2021
|
|
7DSS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dss by Molmil](/molmil-images/mine/7dss) | Complex of FMDV and M8 Nab | Descriptor: | M8 Nab, VP1 of O type FMDV capsid, VP2 of O-type FMDV capsid, ... | Authors: | Dong, H, Liu, P. | Deposit date: | 2021-01-02 | Release date: | 2021-03-31 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural and molecular basis for foot-and-mouth disease virus neutralization by two potent protective antibodies. Protein Cell, 13, 2022
|
|
7DST
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dst by Molmil](/molmil-images/mine/7dst) | FMDV capsid in complex with M170 Nab | Descriptor: | M170 Nab, VP1 of O type FMDV capsid, VP2 of O type FMDV capsid, ... | Authors: | Dong, H, Liu, P. | Deposit date: | 2021-01-02 | Release date: | 2021-03-10 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural and molecular basis for foot-and-mouth disease virus neutralization by two potent protective antibodies. Protein Cell, 13, 2022
|
|
7DN5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dn5 by Molmil](/molmil-images/mine/7dn5) | The cryo-EM structure of human papillomavirus type 58 pseudovirus | Descriptor: | Major capsid protein L1 | Authors: | He, M.Z, Chi, X, Zha, Z.H, Zheng, Q.B, Li, S.W, Xia, N.S. | Deposit date: | 2020-12-08 | Release date: | 2021-01-20 | Method: | ELECTRON MICROSCOPY (4.11 Å) | Cite: | Structural basis for the shared neutralization mechanism of three classes of human papillomavirus type 58 antibodies with disparate modes of binding to be published
|
|
7LVB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lvb by Molmil](/molmil-images/mine/7lvb) | CHOLERA TOXIN B SUBUNIT WITH ATTACHED SIV EPITOPE | Descriptor: | CHLORIDE ION, Cholera enterotoxin B-subunit,Surface protein gp120, TRIETHYLENE GLYCOL, ... | Authors: | Patskovsky, Y, Cardozo, T.J. | Deposit date: | 2021-02-24 | Release date: | 2022-03-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Cholera toxin B scaffolded, focused SIV V2 epitope elicits antibodies that influence the risk of SIV mac251 acquisition in macaques. Front Immunol, 14, 2023
|
|
7UCX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ucx by Molmil](/molmil-images/mine/7ucx) | LRP8 11H1 Fab complexed to a cyclized CR1 peptide | Descriptor: | 11H1 Fab Heavy chain, 11H1 Fab Light chain, Cyclized CR1 peptide, ... | Authors: | Argiriadi, M.A, Deng, K, Egan, D, Gao, L, Gizatullin, F, Harlan, J, Karaoglu, D, Qiu, W, Goodearl, A. | Deposit date: | 2022-03-17 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | The use of cyclic peptide antigens to generate LRP8 specific antibodies Front Drug Discov (Lausanne), 2, 2023
|
|
7WTK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wtk by Molmil](/molmil-images/mine/7wtk) | SARS-CoV-2 Omicron variant spike in complex with Fab XGv286 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of XGv286, ... | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-02-04 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Selection and structural bases of potent broadly neutralizing antibodies from 3-dose vaccinees that are highly effective against diverse SARS-CoV-2 variants, including Omicron sublineages. Cell Res., 32, 2022
|
|
7WTJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wtj by Molmil](/molmil-images/mine/7wtj) | SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv286 | Descriptor: | Heavy chain of XGv286, Light chain of XGv286, Spike protein S1 | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-02-04 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Selection and structural bases of potent broadly neutralizing antibodies from 3-dose vaccinees that are highly effective against diverse SARS-CoV-2 variants, including Omicron sublineages. Cell Res., 32, 2022
|
|