8C9N

MiniCoV-ADDomer, a SARS-CoV-2 epitope presenting viral like particle

Summary for 8C9N

Entry DOI	10.2210/pdb8c9n/pdb
EMDB information	11730 16512
Descriptor	Penton protein (1 entity in total)
Functional Keywords	addomer, vlp, viral, like, particle, ad3, penton, base, vaccine, covid-19, covid, mini-covid, dodecahedron, pb, protein, adenovirus, human, virus like particle
Biological source	Human adenovirus B3
Total number of polymer chains	60
Total formula weight	3997112.82
Authors	Bufton, J.C.,Capin, J.,Boruku, U.,Garzoni, F.,Schaffitzel, C.,Berger, I. (deposition date: 2023-01-23, release date: 2023-12-06, Last modification date: 2023-12-20)
Primary citation	Buzas, D.,Bunzel, A.H.,Staufer, O.,Milodowski, E.J.,Edmunds, G.L.,Bufton, J.C.,Vidana Mateo, B.V.,Yadav, S.K.N.,Gupta, K.,Fletcher, C.,Williamson, M.K.,Harrison, A.,Borucu, U.,Capin, J.,Francis, O.,Balchin, G.,Hall, S.,Vega, M.V.,Durbesson, F.,Lingappa, S.,Vincentelli, R.,Roe, J.,Wooldridge, L.,Burt, R.,Anderson, R.J.L.,Mulholland, A.J.,Hare, J.,Bailey, M.,Davidson, A.D.,Finn, A.,Morgan, D.,Mann, J.,Spatz, J.,Garzoni, F.,Schaffitzel, C.,Berger, I. In vitro generated antibodies guide thermostable ADDomer nanoparticle design for nasal vaccination and passive immunization against SARS-CoV-2. Antib Ther, 6:277-297, 2023 Cited by PubMed: 38075238 DOI: 10.1093/abt/tbad024 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.36 Å)

Structure validation