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7RIH
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BU of 7rih by Molmil
hyen D
Descriptor: CITRATE ANION, Cyclotide hyen-D, D-[I11L]hyen D
Authors:Du, Q, Huang, Y.H, Craik, D.J, Wang, C.K.
Deposit date:2021-07-20
Release date:2021-09-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Enabling efficient folding and high-resolution crystallographic analysis of bracelet cyclotides
Molecules, 26(18), 2021
4OWQ
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BU of 4owq by Molmil
Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 3-methylanthranilate, PRPP and Magnesium
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-azanyl-3-methyl-benzoic acid, Anthranilate phosphoribosyltransferase, ...
Authors:Castell, A, Cookson, T.V.M, Short, F.L, Lott, J.S.
Deposit date:2014-02-03
Release date:2014-04-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.
Biochem.J., 461, 2014
2G48
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BU of 2g48 by Molmil
crystal structure of human insulin-degrading enzyme in complex with amylin
Descriptor: 1,4-DIETHYLENE DIOXIDE, Insulin-degrading enzyme, Islet amyloid polypeptide
Authors:Shen, Y, Tang, W.-J.
Deposit date:2006-02-21
Release date:2006-10-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism.
Nature, 443, 2006
8SBU
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BU of 8sbu by Molmil
Crystal structure of MBP fusion with HPPK from Methanocaldococcus jannaschii
Descriptor: Maltose/maltodextrin-binding periplasmic protein,6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Shaw, G.X, Needle, D, Stair, N.R, Cherry, S, Tropea, J.E, Waugh, D.S, Ji, X.
Deposit date:2023-04-04
Release date:2024-07-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of MBP fusion with HPPK from Methanocaldococcus jannaschii
To be published
7RKV
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BU of 7rkv by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C118 (State 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C118 Fab Heavy Chain, C118 Fab Light Chain, ...
Authors:Barnes, C.O, Jette, C.A, Bjorkman, P.J.
Deposit date:2021-07-22
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies.
Cell Rep, 36, 2021
7RR0
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BU of 7rr0 by Molmil
SARS-CoV-2 receptor binding domain bound to Fab PDI 222
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PDI 222 Fab Heavy Chain, PDI 222 Fab Light Chain, ...
Authors:Pymm, P, Glukhova, A, Black, K.A, Tham, W.H.
Deposit date:2021-08-08
Release date:2021-10-06
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Cell Rep, 37, 2021
7MHT
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BU of 7mht by Molmil
CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX
Descriptor: 5'-D(P*CP*CP*AP*TP*GP*AP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ...
Authors:O'Gara, M, Horton, J.R, Roberts, R.J, Cheng, X.
Deposit date:1998-08-05
Release date:1998-11-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
Nat.Struct.Biol., 5, 1998
4OBS
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BU of 4obs by Molmil
Crystal structure of human alpha-L-iduronidase in the P212121 form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-L-iduronidase, CHLORIDE ION, ...
Authors:Bie, H, Yin, J, He, X, Kermode, A.R, James, M.N.G.
Deposit date:2014-01-07
Release date:2015-01-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystal structure of human alpha-L-iduronidase in the P212121 form
To be Published
7RK2
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BU of 7rk2 by Molmil
Crystal structure of the human astrovirus serotype 8 capsid spike in complex with scFv 2D9, an astrovirus-neutralizing antibody, at 2.65-A resolution
Descriptor: Capsid protein VP25, scFv 2D9
Authors:Meyer, L, Cuellar, C, DuBois, R.M.
Deposit date:2021-07-21
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structures of Two Human Astrovirus Capsid/Neutralizing Antibody Complexes Reveal Distinct Epitopes and Inhibition of Virus Attachment to Cells.
J.Virol., 96, 2022
7MSF
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BU of 7msf by Molmil
MS2 PROTEIN CAPSID/RNA COMPLEX
Descriptor: 5'-R(*UP*CP*GP*CP*CP*AP*AP*CP*AP*GP*GP*CP*GP*G)-3', MS2 PROTEIN CAPSID
Authors:Rowsell, S, Stonehouse, N.J, Convery, M.A, Adams, C.J, Ellington, A.D, Hirao, I, Peabody, D.S, Stockley, P.G, Phillips, S.E.V.
Deposit date:1998-05-20
Release date:1998-11-11
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of a series of RNA aptamers complexed to the same protein target.
Nat.Struct.Biol., 5, 1998
6QUE
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BU of 6que by Molmil
Structure of ovine transhydrogenase in the presence of NADP+ in a "single face-down" conformation
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Nicotinamide nucleotide transhydrogenase
Authors:Kampjut, D, Sazanov, L.A.
Deposit date:2019-02-27
Release date:2019-08-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure and mechanism of mitochondrial proton-translocating transhydrogenase.
Nature, 573, 2019
7ROY
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BU of 7roy by Molmil
The structure of the Fem1B:FNIP1 complex
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Folliculin-interacting protein 1, Protein fem-1 homolog B, ...
Authors:Gee, C.L, Mena, E.L, Manford, A.G, Rape, M.
Deposit date:2021-08-02
Release date:2021-10-13
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis and regulation of the reductive stress response.
Cell, 184, 2021
7RK1
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BU of 7rk1 by Molmil
Crystal structure of the human astrovirus serotype 8 capsid spike in complex with scFv 3E8, an astrovirus-neutralizing antibody, at 2.05-A resolution
Descriptor: Capsid polyprotein VP70, scFv 3E8
Authors:Meyer, L, DuBois, R.M.
Deposit date:2021-07-21
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structures of Two Human Astrovirus Capsid/Neutralizing Antibody Complexes Reveal Distinct Epitopes and Inhibition of Virus Attachment to Cells.
J.Virol., 96, 2022
6QZF
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BU of 6qzf by Molmil
The cryo-EM structure of the collar complex and tail axis in genome emptied bacteriophage phi29
Descriptor: Portal protein, Pre-neck appendage protein, Proximal tail tube connector protein
Authors:Xu, J, Wang, D, Gui, M, Xiang, Y.
Deposit date:2019-03-11
Release date:2019-06-12
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural assembly of the tailed bacteriophage φ29.
Nat Commun, 10, 2019
2G49
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BU of 2g49 by Molmil
Crystal structure of human insulin-degrading enzyme in complex with glucagon
Descriptor: 1,4-DIETHYLENE DIOXIDE, Insulin-degrading enzyme, glucagon preproprotein
Authors:Shen, Y, Tang, W.-J.
Deposit date:2006-02-21
Release date:2006-10-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism.
Nature, 443, 2006
7REP
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BU of 7rep by Molmil
Crystal structure of an engineered variant of single-chain Penicillin G Acylase from Kluyvera cryocrescens (A1-Ac Rd3CHis)
Descriptor: CALCIUM ION, Penicillin G acylase, phenylmethanesulfonic acid
Authors:Orth, P.
Deposit date:2021-07-13
Release date:2021-11-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.192 Å)
Cite:A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins.
Science, 376, 2022
7REO
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BU of 7reo by Molmil
Crystal structure of an engineered variant of single-chain Penicillin G Acylase from Kluyvera cryocrescens (global hydrolysis Rd3CHis)
Descriptor: CALCIUM ION, Penicillin G Acylase
Authors:Orth, P.
Deposit date:2021-07-13
Release date:2021-11-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.812 Å)
Cite:A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins.
Science, 376, 2022
7RDX
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BU of 7rdx by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC - open class
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-11-24
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
7RE1
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BU of 7re1 by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC (composite)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-12-01
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
7RDZ
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BU of 7rdz by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC - apo class
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Helicase, MAGNESIUM ION, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-11-24
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
7RE3
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BU of 7re3 by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC dimer
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-11-24
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
7RE2
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BU of 7re2 by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(1)-RTC
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-12-01
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
7R9G
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BU of 7r9g by Molmil
Catalytically inactive yeast Pseudouridine Synthase, PUS1, bound to RNA
Descriptor: CHLORIDE ION, RNA (5'-R(*AP*AP*AP*UP*CP*GP*GP*GP*AP*UP*UP*CP*CP*GP*GP*AP*UP*A)-3'), SULFATE ION, ...
Authors:Doyle, L.A, Stoddard, B.L.
Deposit date:2021-06-29
Release date:2021-12-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structural basis of mRNA recognition and binding by yeast pseudouridine synthase PUS1.
Plos One, 18, 2023
7R9F
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BU of 7r9f by Molmil
Wild-type yeast Pseudouridine Synthase, PUS1, bound to 5-Fluorouracil RNA
Descriptor: RNA (5'-R(*UP*AP*AP*UP*CP*GP*GP*GP*AP*UP*UP*CP*CP*GP*GP*AP*UP*A)-3'), SULFATE ION, tRNA pseudouridine synthase 1
Authors:Doyle, L.A, Stoddard, B.L.
Deposit date:2021-06-29
Release date:2021-12-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:The structural basis of mRNA recognition and binding by yeast pseudouridine synthase PUS1.
Plos One, 18, 2023
7RDY
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BU of 7rdy by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC - engaged class
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-12-01
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022

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