7B3Q

Crystal structure of c-MET bound by compound 1

Summary for 7B3Q

Entry DOI	10.2210/pdb7b3q/pdb
Descriptor	Hepatocyte growth factor receptor, 1-(phenylmethyl)-5~{H}-pyrrolo[3,2-c]pyridin-4-one, SULFATE ION, ... (4 entities in total)
Functional Keywords	c-met, kinase, folded p-loop, inhibitor, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	34106.53
Authors	Collie, G.W. (deposition date: 2020-12-01, release date: 2020-12-09, Last modification date: 2021-02-03)
Primary citation	Collie, G.W.,Michaelides, I.N.,Embrey, K.,Stubbs, C.J.,Borjesson, U.,Dale, I.L.,Snijder, A.,Barlind, L.,Song, K.,Khurana, P.,Phillips, C.,Storer, R.I. Structural Basis for Targeting the Folded P-Loop Conformation of c-MET. Acs Med.Chem.Lett., 12:162-167, 2021 Cited by PubMed: 33488978 DOI: 10.1021/acsmedchemlett.0c00392 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation