7SNN
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![BU of 7snn by Molmil](/molmil-images/mine/7snn) | Disulfide stabilized HIV-1 CA hexamer in complex with capsid inhibitor N-(1-(3-(4-chloro-1-methyl-3-(methylsulfonamido)-1H-indazol-7-yl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-(3-(difluoromethyl)-5,6-dihydrocyclopenta[c]pyrazol-1(4H)-yl)acetamide | Descriptor: | CHLORIDE ION, Capsid protein p24, IODIDE ION, ... | Authors: | Bester, S.M, Kvaratskhelia, M. | Deposit date: | 2021-10-28 | Release date: | 2022-10-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Disulfide stabilized HIV-1 CA hexamer in complex with capsid inhibitor N-(1-(3-(4-chloro-1-methyl-3-(methylsulfonamido)-1H-indazol-7-yl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-(3-(difluoromethyl)-5,6-dihydrocyclopenta[c]pyrazol-1(4H)-yl)acetamide To Be Published
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4EB7
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![BU of 4eb7 by Molmil](/molmil-images/mine/4eb7) | A. fulgidus IscS-IscU complex structure | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, ... | Authors: | Marinoni, E.N, de Oliveira, J.S, Nicolet, Y, Raulfs, E.C, Amara, P, Dean, D.R, Fontecilla-Camps, J.C. | Deposit date: | 2012-03-23 | Release date: | 2012-05-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | (IscS-IscU)2 complex structures provide insights into Fe2S2 biogenesis and transfer. Angew.Chem.Int.Ed.Engl., 51, 2012
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1NZI
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![BU of 1nzi by Molmil](/molmil-images/mine/1nzi) | Crystal Structure of the CUB1-EGF Interaction Domain of Complement Protease C1s | Descriptor: | CALCIUM ION, Complement C1s component, MAGNESIUM ION | Authors: | Gregory, L.A, Thielens, N.M, Arlaud, G.J, Fontecilla-Camps, J.C, Gaboriaud, C. | Deposit date: | 2003-02-18 | Release date: | 2003-06-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | X-ray structure of the Ca2+-binding interaction domain of C1s. Insights into the assembly of the C1 complex of complement J.Biol.Chem., 278, 2003
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8CF2
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![BU of 8cf2 by Molmil](/molmil-images/mine/8cf2) | Solution structure of the RNA helix formed by the 5'-end of U1 snRNA and an A-1 bulged 5'-splice site in complex with SMN-CY | Descriptor: | 4-[(3~{S})-3-ethylpiperazin-1-yl]-2-fluoranyl-~{N}-(2-methylimidazo[1,2-a]pyrazin-6-yl)benzamide, RNA (5'-R(P*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3') | Authors: | Malard, F, Marquevielle, J, Campagne, S. | Deposit date: | 2023-02-02 | Release date: | 2024-02-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The diversity of splicing modifiers acting on A-1 bulged 5'-splice sites reveals rules for rational drug design. Nucleic Acids Res., 52, 2024
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8JC7
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![BU of 8jc7 by Molmil](/molmil-images/mine/8jc7) | Cryo-EM structure of Vibrio campbellii alpha-hemolysin | Descriptor: | CALCIUM ION, Hemolysin, POTASSIUM ION | Authors: | Wang, C.H, Yeh, M.K, Ho, M.C, Lin, S.M. | Deposit date: | 2023-05-10 | Release date: | 2023-09-27 | Last modified: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (2.06 Å) | Cite: | Structural basis for calcium-stimulating pore formation of Vibrio alpha-hemolysin. Nat Commun, 14, 2023
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1QOJ
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![BU of 1qoj by Molmil](/molmil-images/mine/1qoj) | Crystal Structure of E.coli UvrB C-terminal domain, and a model for UvrB-UvrC interaction. | Descriptor: | UVRB | Authors: | Sohi, M, Alexandrovich, A, Moolenaar, G, Visse, R, Goosen, N, Vernede, X, Fontecilla-Camps, J, Champness, J, Sanderson, M.R. | Deposit date: | 1999-11-10 | Release date: | 2000-11-10 | Last modified: | 2019-03-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of E.Coli Uvrb C-Terminal Domain, and a Model for Uvrb-Uvrc Interaction FEBS Lett., 465, 2000
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1QDD
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![BU of 1qdd by Molmil](/molmil-images/mine/1qdd) | CRYSTAL STRUCTURE OF HUMAN LITHOSTATHINE TO 1.3 A RESOLUTION | Descriptor: | LITHOSTATHINE, beta-D-galactopyranose-(1-3)-[N-acetyl-alpha-neuraminic acid-(2-6)]2-acetamido-2-deoxy-alpha-D-glucopyranose | Authors: | Gerbaud, V, Pignol, D, Loret, E, Bertrand, J.A, Berland, Y, Fontecilla-Camps, J.C, Canselier, J.P, Gabas, N, Verdier, J.M. | Deposit date: | 1999-05-20 | Release date: | 1999-05-28 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Mechanism of calcite crystal growth inhibition by the N-terminal undecapeptide of lithostathine. J.Biol.Chem., 275, 2000
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1T2B
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![BU of 1t2b by Molmil](/molmil-images/mine/1t2b) | Crystal Structure of cytochrome P450cin complexed with its substrate 1,8-cineole | Descriptor: | 1,3,3-TRIMETHYL-2-OXABICYCLO[2.2.2]OCTANE, P450cin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Meharenna, Y.T, Li, H, Hawkes, D.B, Pearson, A.G, De Voss, J, Poulos, T.L. | Deposit date: | 2004-04-20 | Release date: | 2005-04-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of P450cin in a complex with its substrate, 1,8-cineole, a close structural homologue to D-camphor, the substrate for P450cam Biochemistry, 43, 2004
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2VOS
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![BU of 2vos by Molmil](/molmil-images/mine/2vos) | Mycobacterium tuberculosis Folylpolyglutamate synthase complexed with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, COBALT (II) ION, FOLYLPOLYGLUTAMATE SYNTHASE PROTEIN FOLC, ... | Authors: | Young, P.G, Baker, E.N, Metcalf, P, Smith, C.A. | Deposit date: | 2008-02-19 | Release date: | 2008-07-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of Mycobacterium Tuberculosisfolylpolyglutamate Synthase Complexed with Adp and Amppcp. Acta Crystallogr.,Sect.D, 64, 2008
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1T6L
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![BU of 1t6l by Molmil](/molmil-images/mine/1t6l) | Crystal Structure of the Human Cytomegalovirus DNA Polymerase Subunit, UL44 | Descriptor: | DNA polymerase processivity factor | Authors: | Appleton, B.A, Loregian, A, Filman, D.J, Coen, D.M, Hogle, J.M. | Deposit date: | 2004-05-06 | Release date: | 2004-08-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The Cytomegalovirus DNA Polymerase Subunit UL44 Forms a C Clamp-Shaped Dimer. Mol.Cell, 15, 2004
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1A37
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![BU of 1a37 by Molmil](/molmil-images/mine/1a37) | 14-3-3 PROTEIN ZETA BOUND TO PS-RAF259 PEPTIDE | Descriptor: | 14-3-3 PROTEIN ZETA, PS-RAF259 PEPTIDE LSQRQRST(SEP)TPNVHM | Authors: | Petosa, C, Masters, S.C, Pohl, J, Wang, B, Fu, H, Liddington, R.C. | Deposit date: | 1998-01-28 | Release date: | 1999-03-02 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | 14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove. J.Biol.Chem., 273, 1998
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1BC0
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![BU of 1bc0 by Molmil](/molmil-images/mine/1bc0) | RECOMBINANT RAT ANNEXIN V, W185A MUTANT | Descriptor: | ANNEXIN V, CALCIUM ION, SULFATE ION | Authors: | Mo, Y.D, Swairjo, M.A, Li, C.W, Head, J.F, Seaton, B.A. | Deposit date: | 1998-05-04 | Release date: | 1998-11-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components. Biochemistry, 37, 1998
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4F3H
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![BU of 4f3h by Molmil](/molmil-images/mine/4f3h) | The structural of FimXEAL-c-di-GMP from Xanthomonas campestris | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Putative uncharacterized protein | Authors: | Chin, K.-H, Liao, Y.-T, Chou, S.-H. | Deposit date: | 2012-05-09 | Release date: | 2012-11-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural polymorphism of c-di-GMP bound to an EAL domain and in complex with a type II PilZ-domain protein. Acta Crystallogr.,Sect.D, 68, 2012
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4F48
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![BU of 4f48 by Molmil](/molmil-images/mine/4f48) | The X-ray structural of FimXEAL-c-di-GMP-PilZ complexes from Xanthomonas campestris | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Putative uncharacterized protein, Type IV fimbriae assembly protein | Authors: | Chin, K.-H, Liao, Y.-T, Chou, S.-H. | Deposit date: | 2012-05-10 | Release date: | 2012-11-14 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural polymorphism of c-di-GMP bound to an EAL domain and in complex with a type II PilZ-domain protein. Acta Crystallogr.,Sect.D, 68, 2012
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1MSM
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![BU of 1msm by Molmil](/molmil-images/mine/1msm) | The HIV protease (mutant Q7K L33I L63I) complexed with KNI-764 (an inhibitor) | Descriptor: | (4R)-3-{(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylbutanoyl}-5,5-dimethyl-N-(2-methylbenzyl)-1,3-thiazolidine-4-carboxamide, POL polyprotein | Authors: | Vega, S, Kang, L.-W, Velazquez-Campoy, A, Kiso, Y, Amzel, L.M, Freire, E. | Deposit date: | 2002-09-19 | Release date: | 2003-11-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A structural and thermodynamic escape mechanism from a drug resistant mutation of the HIV-1 protease. Proteins, 55, 2004
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1O53
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![BU of 1o53 by Molmil](/molmil-images/mine/1o53) | |
4HVK
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![BU of 4hvk by Molmil](/molmil-images/mine/4hvk) | Crystal structure and functional studies of an unusual L-cysteine desulfurase from Archaeoglobus fulgidus. | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, CALCIUM ION, CHLORIDE ION, ... | Authors: | Yamanaka, Y, Zeppieri, L, Nicolet, Y, Marinoni, E.N, de Oliveira, J.S, Masafumi, O, Dean, D.R, Fontecilla-Camps, J.C. | Deposit date: | 2012-11-06 | Release date: | 2012-12-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Crystal structure and functional studies of an unusual L-cysteine desulfurase from Archaeoglobus fulgidus. Dalton Trans, 42, 2013
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1TUM
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![BU of 1tum by Molmil](/molmil-images/mine/1tum) | MUTT PYROPHOSPHOHYDROLASE-METAL-NUCLEOTIDE-METAL COMPLEX, NMR, 16 STRUCTURES | Descriptor: | COBALT TETRAAMMINE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, ... | Authors: | Lin, J, Abeygunawardana, C, Frick, D.N, Bessman, M.J, Mildvan, A.S. | Deposit date: | 1996-12-05 | Release date: | 1997-05-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the quaternary MutT-M2+-AMPCPP-M2+ complex and mechanism of its pyrophosphohydrolase action. Biochemistry, 36, 1997
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4I8C
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![BU of 4i8c by Molmil](/molmil-images/mine/4i8c) | X-ray structure of NikA in complex with Ni-(L-His)2 | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Lebrette, H, Iannello, M, Fontecilla-Camps, J.C, Cavazza, C. | Deposit date: | 2012-12-03 | Release date: | 2013-01-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.503 Å) | Cite: | The binding mode of Ni-((L)-His)(2) in NikA revealed by X-ray crystallography. J.Inorg.Biochem., 121C, 2012
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1LOA
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![BU of 1loa by Molmil](/molmil-images/mine/1loa) | |
6M54
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![BU of 6m54 by Molmil](/molmil-images/mine/6m54) | Human apo ferritin frozen on TEM grid with Amorphous nickel titanium alloy supporting film | Descriptor: | FE (II) ION, Ferritin heavy chain | Authors: | Huang, X, Zhang, L, Wen, Z, Chen, H, Li, S, Ji, G, Yin, C, Sun, F. | Deposit date: | 2020-03-09 | Release date: | 2020-05-13 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Amorphous nickel titanium alloy film: A new choice for cryo electron microscopy sample preparation. Prog.Biophys.Mol.Biol., 156, 2020
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6APF
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![BU of 6apf by Molmil](/molmil-images/mine/6apf) | Trans-acting transferase from Disorazole synthase complexed with Citrate. | Descriptor: | CITRIC ACID, DisD protein, GLYCEROL, ... | Authors: | Mathews, I.I, Lyubimov, A, Soltis, M, Khosla, C, Cohen, A, Robbins, T. | Deposit date: | 2017-08-17 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | The Conformational Flexibility of the Acyltransferase from the Disorazole Polyketide Synthase Is Revealed by an X-ray Free-Electron Laser Using a Room-Temperature Sample Delivery Method for Serial Crystallography. Biochemistry, 56, 2017
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8D1U
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![BU of 8d1u by Molmil](/molmil-images/mine/8d1u) | E. coli beta-ketoacyl-[acyl carrier protein] synthase III (FabH) with an acetylated cysteine and in complex with oxa(dethia)-Coenzyme A | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] synthase 3, CHLORIDE ION, oxa(dethia)-CoA | Authors: | Benjamin, A.B, Stunkard, L.M, Ling, J, Nice, J.N, Lohman, J.R. | Deposit date: | 2022-05-27 | Release date: | 2022-06-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.302 Å) | Cite: | Structures of chloramphenicol acetyltransferase III and Escherichia coli beta-ketoacylsynthase III co-crystallized with partially hydrolysed acetyl-oxa(dethia)CoA. Acta Crystallogr.,Sect.F, 79, 2023
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6XLC
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![BU of 6xlc by Molmil](/molmil-images/mine/6xlc) | Full-length Hsc82 bound to AMPPNP | Descriptor: | ATP-dependent molecular chaperone HSC82, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Liu, Y.X, Sun, M, Myasnikov, A.G, Elnatan, D, Agard, D.A. | Deposit date: | 2020-06-28 | Release date: | 2021-06-30 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | Full-length Hsc82 bound to AMPPNP To Be Published
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6PIS
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![BU of 6pis by Molmil](/molmil-images/mine/6pis) | |