8JC7

Cryo-EM structure of Vibrio campbellii alpha-hemolysin

Summary for 8JC7

• Entry DOI: 10.2210/pdb8jc7/pdb
• Related: 8JBQ
• EMDB information: 36150
• Descriptor: Hemolysin, POTASSIUM ION, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: vibrio campbellii alpha-hemolysin, pore-forming toxins (pfts), calcium-dependent oligomerization, membrane association, structure-function relationship, toxin
• Biological source: Vibrio campbellii
• Total number of polymer chains: 7
• Total formula weight: 565059.28

Authors

Wang, C.H.,Yeh, M.K.,Ho, M.C.,Lin, S.M. (deposition date: 2023-05-10, release date: 2023-09-27, Last modification date: 2023-10-04)

• Primary citation: Chiu, Y.C.,Yeh, M.C.,Wang, C.H.,Chen, Y.A.,Chang, H.,Lin, H.Y.,Ho, M.C.,Lin, S.M.; Structural basis for calcium-stimulating pore formation of Vibrio alpha-hemolysin.; Nat Commun, 14:5946-5946, 2023; PubMed: 37741869; DOI: 10.1038/s41467-023-41579-x

Experimental method

ELECTRON MICROSCOPY (2.06 Å)