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6C16
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BU of 6c16 by Molmil
Ubiquitin variant (UbV.Fbl10.1) bound to a human Skp1-Fbl11 fragment complex.
Descriptor: Lysine-specific demethylase 2A, Polyubiquitin-B, S-phase kinase-associated protein 1
Authors:Manczyk, N, Sicheri, F.
Deposit date:2018-01-04
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
2ZVN
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BU of 2zvn by Molmil
NEMO CoZi domain incomplex with diubiquitin in P212121 space group
Descriptor: NF-kappa-B essential modulator, UBC protein
Authors:Rahighi, S, Ikeda, F, Kawasaki, M, Akutsu, M, Suzuki, N, Kato, R, Kensche, T, Uejima, T, Bloor, S, Komander, D, Randow, F, Wakatsuki, S, Dikic, I.
Deposit date:2008-11-12
Release date:2009-03-24
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
Cell(Cambridge,Mass.), 136, 2009
6BVA
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BU of 6bva by Molmil
Ubiquitin Variant (UbV.Fl10.1) bound to a human Skp1-Fbl10 fragment complex.
Descriptor: Lysine-specific demethylase 2B, Polyubiquitin-B, S-phase kinase-associated protein 1
Authors:Manczyk, N, Sicheri, F.
Deposit date:2017-12-12
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
6BYH
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BU of 6byh by Molmil
Ubiquitin Variant (UbV.Fl11.1) bound to a human Skp1-Fbl11 fragment complex.
Descriptor: Lysine-specific demethylase 2A, Polyubiquitin-B, S-phase kinase-associated protein 1
Authors:Manczyk, N, Sicheri, F.
Deposit date:2017-12-20
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
6DC6
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BU of 6dc6 by Molmil
Crystal structure of human ubiquitin activating enzyme E1 (Uba1) in complex with ubiquitin
Descriptor: MAGNESIUM ION, PYROPHOSPHATE 2-, Ubiquitin, ...
Authors:Lv, Z, Yuan, L, Williams, K.M, Atkison, J.H, Olsen, S.K.
Deposit date:2018-05-04
Release date:2018-10-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Crystal structure of a human ubiquitin E1-ubiquitin complex reveals conserved functional elements essential for activity.
J. Biol. Chem., 293, 2018
6DGF
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BU of 6dgf by Molmil
Ubiquitin Variant bound to USP2
Descriptor: Polyubiquitin-B, SULFATE ION, Ubiquitin carboxyl-terminal hydrolase 2, ...
Authors:Manczyk, N, Sicheri, F.
Deposit date:2018-05-17
Release date:2019-02-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Yeast Two-Hybrid Analysis for Ubiquitin Variant Inhibitors of Human Deubiquitinases.
J. Mol. Biol., 431, 2019
2ZVO
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BU of 2zvo by Molmil
NEMO CoZi domain in complex with diubiquitin in C2 space group
Descriptor: NF-kappa-B essential modulator, UBC protein
Authors:Rahighi, S, Ikeda, F, Kawasaki, M, Akutsu, M, Suzuki, N, Kato, R, Kensche, T, Uejima, T, Bloor, S, Komander, D, Randow, F, Wakatsuki, S, Dikic, I.
Deposit date:2008-11-12
Release date:2009-03-24
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
Cell(Cambridge,Mass.), 136, 2009
2Z59
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BU of 2z59 by Molmil
Complex Structures of Mouse Rpn13 (22-130aa) and ubiquitin
Descriptor: Protein ADRM1, Ubiquitin
Authors:Chen, X, Schreiner, P, Groll, M, Walters, K.J.
Deposit date:2007-07-01
Release date:2008-05-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction.
Nature, 453, 2008
3BY4
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BU of 3by4 by Molmil
Structure of Ovarian Tumor (OTU) domain in complex with Ubiquitin
Descriptor: 3-AMINOPROPANE, Ubiquitin, Ubiquitin thioesterase OTU1
Authors:Messick, T.E, Marmorstein, R.
Deposit date:2008-01-15
Release date:2008-02-19
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein
J.Biol.Chem., 283, 2008
3C0R
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BU of 3c0r by Molmil
Structure of Ovarian Tumor (OTU) domain in complex with Ubiquitin
Descriptor: 3-AMINOPROPANE, Ubiquitin, Ubiquitin thioesterase OTU1
Authors:Messick, T.E, Marmorstein, R.
Deposit date:2008-01-21
Release date:2008-02-19
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.315 Å)
Cite:Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein
J.Biol.Chem., 283, 2008
3AI5
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BU of 3ai5 by Molmil
Crystal structure of yeast enhanced green fluorescent protein-ubiquitin fusion protein
Descriptor: 1,2-ETHANEDIOL, yeast enhanced green fluorescent protein,Ubiquitin
Authors:Suzuki, N, Wakatsuki, S, Kawasaki, M.
Deposit date:2010-05-10
Release date:2010-09-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystallization of small proteins assisted by green fluorescent protein
Acta Crystallogr.,Sect.D, 66, 2010
3PRM
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BU of 3prm by Molmil
Structural analysis of a viral OTU domain protease from the Crimean-Congo Hemorrhagic Fever virus in complex with human ubiquitin
Descriptor: Polyubiquitin-B (Fragment), RNA-directed RNA polymerase L
Authors:Capodagli, G.C, McKercher, M.A, Baker, E.A, Masters, E.M, Brunzelle, J.S, Pegan, S.D.
Deposit date:2010-11-30
Release date:2011-01-26
Last modified:2023-02-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis of a viral ovarian tumor domain protease from the crimean-congo hemorrhagic Fever virus in complex with covalently bonded ubiquitin.
J.Virol., 85, 2011
3Q3F
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BU of 3q3f by Molmil
Engineering Domain-Swapped Binding Interfaces by Mutually Exclusive Folding: Insertion of Ubiquitin into position 103 of Barnase
Descriptor: Ribonuclease/Ubiquitin chimeric protein, SULFATE ION
Authors:Ha, J.-H, Karchin, J.M, Walker-Kopp, N, Huang, L.-S, Berry, E.A, Loh, S.N.
Deposit date:2010-12-21
Release date:2012-01-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.169 Å)
Cite:Engineering domain-swapped binding interfaces by mutually exclusive folding.
J.Mol.Biol., 416, 2012
3PLU
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BU of 3plu by Molmil
Structure of Hub-1 protein in complex with Snu66 peptide (HINDI)
Descriptor: 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Ubiquitin-like modifier HUB1
Authors:Mishra, S.K, Ammon, T, Popowicz, G.M, Krajewski, M, Nagel, R.J, Ares, M, Holak, T.A, Jentsch, S.
Deposit date:2010-11-15
Release date:2011-06-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing.
Nature, 474, 2011
3PHX
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BU of 3phx by Molmil
OTU Domain of Crimean Congo Hemorrhagic Fever Virus in complex with ISG15
Descriptor: ACETIC ACID, ETHANAMINE, RNA-directed RNA polymerase L, ...
Authors:Akutsu, M, Ye, Y, Virdee, S, Komander, D.
Deposit date:2010-11-04
Release date:2011-02-02
Last modified:2014-08-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains.
Proc.Natl.Acad.Sci.USA, 108, 2011
3PGE
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BU of 3pge by Molmil
Structure of sumoylated PCNA
Descriptor: Proliferating cell nuclear antigen, SUMO-modified proliferating cell nuclear antigen
Authors:Freudenthal, B.D, Brogie, J.E, Gakhar, L, Washington, T.
Deposit date:2010-11-01
Release date:2010-12-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of SUMO-Modified Proliferating Cell Nuclear Antigen.
J.Mol.Biol., 406, 2011
3PHD
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BU of 3phd by Molmil
Crystal structure of human HDAC6 in complex with ubiquitin
Descriptor: Histone deacetylase 6, Polyubiquitin, ZINC ION
Authors:Dong, A, Qui, W, Ravichandran, M, Schuetz, A, Loppnau, P, Li, F, Mackenzie, F, Kozieradzki, I, Ouyang, H, Structural Genomics Consortium (SGC)
Deposit date:2010-11-03
Release date:2011-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Protein Aggregates Are Recruited to Aggresome by Histone Deacetylase 6 via Unanchored Ubiquitin C Termini.
J.Biol.Chem., 287, 2012
3PLV
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BU of 3plv by Molmil
Structure of Hub-1 protein in complex with Snu66 peptide (HINDII)
Descriptor: 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Ubiquitin-like modifier HUB1
Authors:Mishra, S.K, Ammon, T, Popowicz, G.M, Krajewski, M, Nagel, R.J, Ares, M, Holak, T.A, Jentsch, S.
Deposit date:2010-11-15
Release date:2011-06-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing.
Nature, 474, 2011
3PRP
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BU of 3prp by Molmil
Structural analysis of a viral OTU domain protease from the Crimean-Congo Hemorrhagic Fever virus in complex with human ubiquitin
Descriptor: Polyubiquitin-B (Fragment), RNA-directed RNA polymerase L
Authors:Capodagli, G.C, McKercher, M.A, Baker, E.A, Masters, E.M, Brunzelle, J.S, Pegan, S.D.
Deposit date:2010-11-30
Release date:2011-01-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.699 Å)
Cite:Structural analysis of a viral ovarian tumor domain protease from the crimean-congo hemorrhagic Fever virus in complex with covalently bonded ubiquitin.
J.Virol., 85, 2011
3PSE
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BU of 3pse by Molmil
Structure of a viral OTU domain protease bound to interferon-stimulated gene 15 (ISG15)
Descriptor: 1.7.6 3-bromanylpropan-1-amine, GLYCEROL, RNA polymerase, ...
Authors:Bacik, J.P, James, T.W, Frias-Staheli, N, Garcia-Sastre, A, Mark, B.L.
Deposit date:2010-12-01
Release date:2011-01-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.
Proc.Natl.Acad.Sci.USA, 108, 2011
3PHW
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BU of 3phw by Molmil
OTU Domain of Crimean Congo Hemorrhagic Fever Virus in complex with Ubiquitin
Descriptor: ETHANAMINE, RNA-directed RNA polymerase L, Ubiquitin-40S ribosomal protein S27a
Authors:Akutsu, M, Ye, Y, Virdee, S, Komander, D.
Deposit date:2010-11-04
Release date:2011-02-02
Last modified:2014-08-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains.
Proc.Natl.Acad.Sci.USA, 108, 2011
3PT2
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BU of 3pt2 by Molmil
Structure of a viral OTU domain protease bound to Ubiquitin
Descriptor: 1.7.6 3-bromanylpropan-1-amine, ACETATE ION, RNA polymerase, ...
Authors:James, T.W, Bacik, J.P, Frias-Staheli, N, Garcia-Sastre, A, Mark, B.L.
Deposit date:2010-12-02
Release date:2011-01-19
Last modified:2023-05-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.
Proc.Natl.Acad.Sci.USA, 108, 2011
3OLM
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BU of 3olm by Molmil
Structure and Function of a Ubiquitin Binding Site within the Catalytic Domain of a HECT Ubiquitin Ligase
Descriptor: E3 ubiquitin-protein ligase RSP5, Ubiquitin
Authors:Kim, H.C, Steffen, A, Chen, J, Huibregtse, J.M.
Deposit date:2010-08-26
Release date:2011-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.495 Å)
Cite:Structure and function of a HECT domain ubiquitin-binding site.
Embo Rep., 12, 2011
5HPS
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BU of 5hps by Molmil
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: WWP1 and UbV P1.1
Descriptor: Ubiquitin variant P1.1, WWP1 HECT
Authors:Wu, K.-P, Mercredi, P.Y, Schulman, B.A.
Deposit date:2016-01-20
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
3RT3
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BU of 3rt3 by Molmil
Complex of influenza virus protein with host anti-viral factor
Descriptor: Non-structural protein 1, SUCCINIC ACID, Ubiquitin-like protein ISG15
Authors:Wang, X.Q, Li, L.
Deposit date:2011-05-03
Release date:2011-07-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:Crystal structure of human ISG15 in complex with influenza B virus NS1B
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