8ERH
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8ERG
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2Z7B
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![BU of 2z7b by Molmil](/molmil-images/mine/2z7b) | Crystal Structure of Mesorhizobium loti 3-hydroxy-2-methylpyridine-4,5-dicarboxylate decarboxylase | Descriptor: | MANGANESE (II) ION, Mlr6791 protein | Authors: | McCulloch, K.M, Mukherjee, T, Ealick, S.E, Begley, T.P. | Deposit date: | 2007-08-17 | Release date: | 2007-11-13 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Gene Identification and Structural Characterization of the Pyridoxal 5'-Phosphate Degradative Protein 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate Decarboxylase from Mesorhizobium loti MAFF303099 Biochemistry, 46, 2007
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6LNI
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![BU of 6lni by Molmil](/molmil-images/mine/6lni) | Cryo-EM structure of amyloid fibril formed by full-length human prion protein | Descriptor: | Major prion protein | Authors: | Wang, L.Q, Zhao, K, Yuan, H.Y, Wang, Q, Guan, Z.Y, Tao, J, Li, X.N, Hao, M.M, Chen, J, Zhang, D.L, Zhu, H.L, Yin, P, Liu, C, Liang, Y. | Deposit date: | 2019-12-30 | Release date: | 2020-06-10 | Last modified: | 2020-06-24 | Method: | ELECTRON MICROSCOPY (2.702 Å) | Cite: | Cryo-EM structure of an amyloid fibril formed by full-length human prion protein. Nat.Struct.Mol.Biol., 27, 2020
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6XRW
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![BU of 6xrw by Molmil](/molmil-images/mine/6xrw) | Chromosomal ParDE TA system from P. aeruginosa | Descriptor: | BENZAMIDINE, GLYCEROL, NONAETHYLENE GLYCOL, ... | Authors: | Bourne, C.R, Snead, K.J, Thomas, L.M. | Deposit date: | 2020-07-13 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | ParD Antitoxin Hotspot Alters a Disorder-to-Order Transition upon Binding to Its Cognate ParE Toxin, Lessening Its Interaction Affinity and Increasing Its Protease Degradation Kinetics. Biochemistry, 61, 2022
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8FJ0
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![BU of 8fj0 by Molmil](/molmil-images/mine/8fj0) | Crystal Structure of the Tick Evasin EVA-AAM1001(Y44A) Complexed to Human Chemokine CCL2 | Descriptor: | C-C motif chemokine 2, Evasin P1243 | Authors: | Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J. | Deposit date: | 2022-12-18 | Release date: | 2023-03-29 | Last modified: | 2023-07-26 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins. Nat Commun, 14, 2023
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8FX9
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8FUZ
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![BU of 8fuz by Molmil](/molmil-images/mine/8fuz) | Human IMPDH2 mutant - L245P, treated with GTP, ATP, IMP, and NAD+; filament assembly interface reconstruction | Descriptor: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | O'Neill, A.G, Kollman, J.M. | Deposit date: | 2023-01-18 | Release date: | 2023-04-19 | Last modified: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (2.1 Å) | Cite: | Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation. J.Biol.Chem., 299, 2023
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7DWV
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![BU of 7dwv by Molmil](/molmil-images/mine/7dwv) | Cryo-EM structure of amyloid fibril formed by familial prion disease-related mutation E196K | Descriptor: | Major prion protein | Authors: | Wang, L.Q, Zhao, K, Yuan, H.Y, Li, X.N, Dang, H.B, Ma, Y.Y, Wang, Q, Wang, C, Sun, Y.P, Chen, J, Li, D, Zhang, D.L, Yin, P, Liu, C, Liang, Y. | Deposit date: | 2021-01-18 | Release date: | 2021-10-13 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Genetic prion disease-related mutation E196K displays a novel amyloid fibril structure revealed by cryo-EM. Sci Adv, 7, 2021
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6XYP
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![BU of 6xyp by Molmil](/molmil-images/mine/6xyp) | Multiple system atrophy Type II-1 alpha-synuclein filament | Descriptor: | Alpha-synuclein | Authors: | Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M. | Deposit date: | 2020-01-30 | Release date: | 2020-02-12 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.29 Å) | Cite: | Structures of alpha-synuclein filaments from multiple system atrophy. Nature, 585, 2020
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5JLH
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![BU of 5jlh by Molmil](/molmil-images/mine/5jlh) | Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 2, ... | Authors: | von der Ecken, J, Heissler, S.M, Pathan-Chhatbar, S, Manstein, D.J, Raunser, S. | Deposit date: | 2016-04-27 | Release date: | 2016-06-15 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution. Nature, 534, 2016
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8I9Q
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![BU of 8i9q by Molmil](/molmil-images/mine/8i9q) | The focused refinement of CCT4-PhLP2A from TRiC-PhLP2A complex in the open state | Descriptor: | Phosducin-like protein 3, T-complex protein 1 subunit delta | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | Deposit date: | 2023-02-07 | Release date: | 2023-12-20 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.22 Å) | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle. Nat Commun, 15, 2024
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8IB8
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![BU of 8ib8 by Molmil](/molmil-images/mine/8ib8) | Human TRiC-PhLP2A-actin complex in the closed state | Descriptor: | ACTB protein (Fragment), Phosducin-like protein 3, T-complex protein 1 subunit alpha, ... | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | Deposit date: | 2023-02-09 | Release date: | 2023-12-20 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.42 Å) | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle. Nat Commun, 15, 2024
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6C48
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![BU of 6c48 by Molmil](/molmil-images/mine/6c48) | Crystal structure of B-Myb-LIN9-LIN52 complex | Descriptor: | Myb-related protein B, Protein lin-52 homolog, Protein lin-9 homolog, ... | Authors: | Guiley, K.Z, Tripathi, S.M, Rubin, S.M. | Deposit date: | 2018-01-11 | Release date: | 2018-09-19 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Structural mechanism of Myb-MuvB assembly. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8I9U
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![BU of 8i9u by Molmil](/molmil-images/mine/8i9u) | Human TRiC-PhLP2A complex in the open state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Phosducin-like protein 3, T-complex protein 1 subunit alpha, ... | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | Deposit date: | 2023-02-07 | Release date: | 2024-01-17 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle. Nat Commun, 15, 2024
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8I1U
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![BU of 8i1u by Molmil](/molmil-images/mine/8i1u) | Human TRiC-PhLP2A complex in the closed state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | Deposit date: | 2023-01-13 | Release date: | 2024-01-31 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle. Nat Commun, 15, 2024
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8I6J
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![BU of 8i6j by Molmil](/molmil-images/mine/8i6j) | The focused refinement of CCT3-PhLP2A from TRiC-PhLP2A complex in the open state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Phosducin-like protein 3, T-complex protein 1 subunit gamma | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | Deposit date: | 2023-01-28 | Release date: | 2024-01-31 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle. Nat Commun, 15, 2024
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8AYZ
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![BU of 8ayz by Molmil](/molmil-images/mine/8ayz) | Poliovirus type 2 (strain MEF-1) virus-like particle in complex with capsid binder compound 17 | Descriptor: | 4-[[4-[1,3-bis(oxidanylidene)isoindol-2-yl]phenyl]sulfonylamino]benzoic acid, Capsid protein, VP0, ... | Authors: | Bahar, M.W, Fry, E.E, Stuart, D.I. | Deposit date: | 2022-09-04 | Release date: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (1.88 Å) | Cite: | A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation. Commun Biol, 5, 2022
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8AYY
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![BU of 8ayy by Molmil](/molmil-images/mine/8ayy) | Poliovirus type 3 (strain Saukett) stabilised virus-like particle (PV3 SC8) in complex with GSH and Pleconaril | Descriptor: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, Capsid protein, VP0, ... | Authors: | Bahar, M.W, Fry, E.E, Stuart, D.I. | Deposit date: | 2022-09-04 | Release date: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation. Commun Biol, 5, 2022
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8AYX
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![BU of 8ayx by Molmil](/molmil-images/mine/8ayx) | Poliovirus type 3 (strain Saukett) stabilised virus-like particle (PV3 SC8) in complex with GSH and GPP3 | Descriptor: | 1-[(3S)-5-[4-[(E)-ETHOXYIMINOMETHYL]PHENOXY]-3-METHYL-PENTYL]-3-PYRIDIN-4-YL-IMIDAZOLIDIN-2-ONE, Capsid protein, VP0, ... | Authors: | Bahar, M.W, Fry, E.E, Stuart, D.I. | Deposit date: | 2022-09-04 | Release date: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation. Commun Biol, 5, 2022
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6BVB
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![BU of 6bvb by Molmil](/molmil-images/mine/6bvb) | Crystal structure of HIF-2alpha-pVHL-elongin B-elongin C | Descriptor: | Elongin-B, Elongin-C, Hypoxia-Inducible Factor 2 alpha, ... | Authors: | Tarade, D, Ohh, M, Lee, J.E. | Deposit date: | 2017-12-12 | Release date: | 2018-08-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | HIF-2 alpha-pVHL complex reveals broad genotype-phenotype correlations in HIF-2 alpha-driven disease. Nat Commun, 9, 2018
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8GJZ
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![BU of 8gjz by Molmil](/molmil-images/mine/8gjz) | Structure of a STING receptor from S. pistillata Sp-STING1 bound to 2'3'-cUA | Descriptor: | 2'3'-cUA, Stimulator of interferon genes protein | Authors: | Li, Y, Toyoda, H, Slavik, K.M, Morehouse, B.R, Kranzusch, P.J. | Deposit date: | 2023-03-16 | Release date: | 2023-07-05 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
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6XYQ
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![BU of 6xyq by Molmil](/molmil-images/mine/6xyq) | Multiple system atrophy Type II-2 alpha-synuclein filament | Descriptor: | Alpha-synuclein | Authors: | Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M. | Deposit date: | 2020-01-30 | Release date: | 2020-02-12 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Structures of alpha-synuclein filaments from multiple system atrophy. Nature, 585, 2020
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5VMS
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![BU of 5vms by Molmil](/molmil-images/mine/5vms) | CryoEM structure of Xenopus KCNQ1 channel | Descriptor: | CALCIUM ION, Calmodulin, Potassium voltage-gated channel subfamily KQT member 1 | Authors: | Mackinnon, R, Sun, J. | Deposit date: | 2017-04-28 | Release date: | 2017-06-07 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Cryo-EM Structure of a KCNQ1/CaM Complex Reveals Insights into Congenital Long QT Syndrome. Cell, 169, 2017
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5WBX
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![BU of 5wbx by Molmil](/molmil-images/mine/5wbx) | |