8AYY

Poliovirus type 3 (strain Saukett) stabilised virus-like particle (PV3 SC8) in complex with GSH and Pleconaril

Summary for 8AYY

• Entry DOI: 10.2210/pdb8ayy/pdb
• Related: 8AYX 8AYZ
• EMDB information: 15725 15726 15727
• Descriptor: Capsid protein, VP1, Capsid protein, VP0, Capsid protein, VP3, ... (5 entities in total)
• Functional Keywords: capsid protein, virus like particle, glutathione, inhibitor, complex
• Biological source: Human poliovirus 3; More
• Total number of polymer chains: 3
• Total formula weight: 98189.58

Authors

Bahar, M.W.,Fry, E.E.,Stuart, D.I. (deposition date: 2022-09-04, release date: 2022-12-07)

• Primary citation: Bahar, M.W.,Nasta, V.,Fox, H.,Sherry, L.,Grehan, K.,Porta, C.,Macadam, A.J.,Stonehouse, N.J.,Rowlands, D.J.,Fry, E.E.,Stuart, D.I.; A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation.; Commun Biol, 5:1293-1293, 2022; PubMed: 36434067; DOI: 10.1038/s42003-022-04252-5

Experimental method

ELECTRON MICROSCOPY (2.6 Å)