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1F93
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BU of 1f93 by Molmil
CRYSTAL STRUCTURE OF A COMPLEX BETWEEN THE DIMERIZATION DOMAIN OF HNF-1 ALPHA AND THE COACTIVATOR DCOH
Descriptor: DIMERIZATION COFACTOR OF HEPATOCYTE NUCLEAR FACTOR 1-ALPHA, HEPATOCYTE NUCLEAR FACTOR 1-ALPHA
Authors:Rose, R.B, Bayle, J.H, Endrizzi, J.A, Cronk, J.D, Crabtree, G.R, Alber, T.
Deposit date:2000-07-06
Release date:2000-09-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of dimerization, coactivator recognition and MODY3 mutations in HNF-1alpha.
Nat.Struct.Biol., 7, 2000
8WHI
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BU of 8whi by Molmil
Crystal structure of native CLASP2 in complex with CLIP170
Descriptor: 1,2-ETHANEDIOL, CLIP-associating protein 2, CLIP1 protein, ...
Authors:Jin, G, Wei, Z.
Deposit date:2023-09-23
Release date:2024-08-28
Method:X-RAY DIFFRACTION (1.853 Å)
Cite:CLASP-mediated competitive binding in protein condensates directs microtubule growth.
Nat Commun, 15, 2024
8DC1
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BU of 8dc1 by Molmil
Structural and biochemical characterization of L. interrogans Lsa45 reveals a penicillin-binding protein with esterase activity
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IODIDE ION, ...
Authors:Santos, J.C, Nascimento, A.L.T.O.
Deposit date:2022-06-15
Release date:2023-01-11
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structural and biochemical characterization of Leptospira interrogans Lsa45 reveals a penicillin-binding protein with esterase activity.
Process Biochem, 125, 2023
6X0O
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BU of 6x0o by Molmil
Single-Particle Cryo-EM Structure of Arabinosyltransferase EmbB from Mycobacterium smegmatis
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, CALCIUM ION, Integral membrane indolylacetylinositol arabinosyltransferase EmbB
Authors:Tan, Y.Z, Rodrigues, J, Keener, J.E, Zheng, R.B, Brunton, R, Kloss, B, Giacometti, S.I, Rosario, A.L, Zhang, L, Niederweis, M, Clarke, O.B, Lowary, T.L, Marty, M.T, Archer, M, Potter, C.S, Carragher, B, Mancia, F.
Deposit date:2020-05-17
Release date:2020-06-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of arabinosyltransferase EmbB from Mycobacterium smegmatis.
Nat Commun, 11, 2020
8DJD
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BU of 8djd by Molmil
CRYSTAL STRUCTURE OF GLYCOGEN SYNTHASE KINASE 3 BETA COMPLEXED WITH 3-[(CYCLOPROPYLMETHYL)AMINO] -N-(4-PHENYLPYRIDIN-3-YL)IMIDAZO[1,2-B]PYRIDAZINE-8-CARBOX AMIDE
Descriptor: 2-[(cyclopropanecarbonyl)amino]-N-(5-phenylpyridin-3-yl)pyridine-4-carboxamide, Glycogen synthase kinase-3 beta
Authors:Lewis, H.A, Muckelbauer, J.K.
Deposit date:2022-06-30
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.205 Å)
Cite:Structure-activity relationship (SAR) studies on substituted N-(pyridin-3-yl)-2-amino-isonicotinamides as highly potent and selective glycogen synthase kinase-3 (GSK-3) inhibitors.
Bioorg.Med.Chem.Lett., 81, 2023
7R6O
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BU of 7r6o by Molmil
Pyrrolysyl-tRNA synthetase from methanogenic archaeon ISO4-G1 (G1PylRS)
Descriptor: 1,2-ETHANEDIOL, Pyrrolysyl-tRNA synthetase PylS, SULFATE ION
Authors:Frkic, R.L, Huber, T, Jackson, C.J.
Deposit date:2021-06-23
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Genetic Encoding of Cyanopyridylalanine for In-Cell Protein Macrocyclization by the Nitrile-Aminothiol Click Reaction.
Angew.Chem.Int.Ed.Engl., 61, 2022
8W9H
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BU of 8w9h by Molmil
Crystal structure of anti-human CLEC12A antibody 50C1
Descriptor: 1,2-ETHANEDIOL, SULFATE ION, anti-human CLEC12A antibody 50C1 Fab Heavy chain, ...
Authors:Mori, S, Nagae, M, Yamasaki, S.
Deposit date:2023-09-05
Release date:2024-03-06
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands.
Int.Immunol., 36, 2024
1FBR
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BU of 1fbr by Molmil
FOURTH AND FIFTH FIBRONECTIN TYPE I MODULE PAIR
Descriptor: FIBRONECTIN
Authors:Phan, I.Q.H, Williams, M.J, Campbell, I.D.
Deposit date:1995-08-08
Release date:1995-10-15
Last modified:2024-11-13
Method:SOLUTION NMR
Cite:Solution structure of a pair of fibronectin type 1 modules with fibrin binding activity.
J.Mol.Biol., 235, 1994
6WZK
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BU of 6wzk by Molmil
LY3041658 Fab bound to CXCL3
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, C-X-C motif chemokine 3, ...
Authors:Durbin, J.D, Druzina, Z.
Deposit date:2020-05-14
Release date:2020-11-25
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody.
Mabs, 12
6Z2O
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BU of 6z2o by Molmil
Crystal structure of wild type OgpA from Akkermansia muciniphila in P 21 21 21
Descriptor: 1,2-ETHANEDIOL, O-glycan protease, ZINC ION
Authors:Trastoy, B, Naegali, A, Anso, I, Sjogren, J, Guerin, M.E.
Deposit date:2020-05-18
Release date:2020-09-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.649 Å)
Cite:Structural basis of mammalian mucin processing by the human gut O-glycopeptidase OgpA from Akkermansia muciniphila.
Nat Commun, 11, 2020
1FLE
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BU of 1fle by Molmil
CRYSTAL STRUCTURE OF ELAFIN COMPLEXED WITH PORCINE PANCREATIC ELASTASE
Descriptor: ELAFIN, ELASTASE
Authors:Tsunemi, M, Matsuura, Y, Sakakibara, S, Katsube, Y.
Deposit date:1996-07-04
Release date:1997-01-11
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution.
Biochemistry, 35, 1996
6VZ6
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BU of 6vz6 by Molmil
Methanococcoides burtonii cytochrome b5 domain protein (WP 011499504.1)
Descriptor: Cytochrome b5-domain protein, PROTOPORPHYRIN IX CONTAINING FE
Authors:Teakel, S.L, Forwood, J.K, Aragao, D, Cahill, M.A, Marama, M.
Deposit date:2020-02-27
Release date:2020-03-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Methanococcoides burtonii cytochrome b5 domain protein (WP 011499504.1)
To Be Published
8DMR
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BU of 8dmr by Molmil
Legionella macrodomain effector MavL R370A in complex with ADP-ribose
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MavL, ...
Authors:Zhang, Z, Das, C.
Deposit date:2022-07-08
Release date:2023-07-12
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain.
Nat Commun, 15, 2024
7RHD
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BU of 7rhd by Molmil
darkmRuby M94T/F96Y mutant at pH 7.5
Descriptor: 1,2-ETHANEDIOL, darkmRuby M94T/F96Y mutant
Authors:Huang, M, Ng, H.L, Zhang, S, Deng, M, Chu, J.
Deposit date:2021-07-16
Release date:2022-07-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Long-range Interaction Affects Brightness and pH Stability of a Dark Fluorescent Protein
To Be Published
6Z0K
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BU of 6z0k by Molmil
Crystal structure of laccase from Pediococcus acidilactici Pp5930 (Hepes pH 7.5)
Descriptor: 1,2-ETHANEDIOL, COPPER (II) ION, Putative multicopper oxidase mco
Authors:Casino, P, Huesa, J, Pardo, I.
Deposit date:2020-05-09
Release date:2021-03-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis and biochemical properties of laccase enzymes from two Pediococcus species.
Microb Biotechnol, 14, 2021
6XYV
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BU of 6xyv by Molmil
NMR solution structure of the Iron-Sulfur protein PioC from Rhodopseudomonas palustris TIE-1
Descriptor: IRON/SULFUR CLUSTER, PioC
Authors:Cantini, F, Trindade, I.
Deposit date:2020-01-31
Release date:2020-11-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:PRE-driven protein NMR structures: an alternative approach in highly paramagnetic systems.
Febs J., 288, 2021
5FAA
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BU of 5faa by Molmil
Crystal structure of C-terminal domain of shaft pilin spaA from Lactobacillus rhamnosus GG, - I422 space group
Descriptor: 1,2-ETHANEDIOL, Cell surface protein SpaA
Authors:Chaurasia, P, Pratap, S, von Ossowski, I, Palva, A, Krishnan, V.
Deposit date:2015-12-11
Release date:2016-07-20
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:New insights about pilus formation in gut-adapted Lactobacillus rhamnosus GG from the crystal structure of the SpaA backbone-pilin subunit
Sci Rep, 6, 2016
6X83
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BU of 6x83 by Molmil
Crystal Structure of TNFalpha with fragment compound 6
Descriptor: 1-benzyl-1H-benzimidazole, Tumor necrosis factor
Authors:Longenecker, K.L, Stoll, V.S.
Deposit date:2020-06-01
Release date:2021-01-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Development of Orally Efficacious Allosteric Inhibitors of TNF alpha via Fragment-Based Drug Design.
J.Med.Chem., 64, 2021
7S6F
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BU of 7s6f by Molmil
Crystal structure of UrtA1 from Synechococcus WH8102 in complex with urea and calcium
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Putative urea ABC transporter, ...
Authors:Shah, B.S, Mikolajek, H, Orr, C.M, Mykhaylyk, V, Owens, R.J, Paulsen, I.T.
Deposit date:2021-09-14
Release date:2021-10-20
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of UrtA1 from Synechococcus WH8102 in complex with urea and calcium
To Be Published
8EHB
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BU of 8ehb by Molmil
Structure of Tannerella forsythia selenomethionine-derivatized potempin D mutant I53M
Descriptor: 1,2-ETHANEDIOL, Putative lipoprotein
Authors:Gomis-Ruth, F.X.
Deposit date:2022-09-14
Release date:2022-12-21
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A unique network of attack, defence and competence on the outer membrane of the periodontitis pathogen Tannerella forsythia.
Chem Sci, 14, 2023
9AX1
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BU of 9ax1 by Molmil
Structure of full-length amyloidogenic immunoglobulin light chain H9 in complex with 2-(6-methyl-2-oxo-4-(2-phenylpropoxy)pyridin-1(2H)-yl)ethyl (3-(1H-imidazol-4-yl)benzyl)carbamate
Descriptor: 2-{6-methyl-2-oxo-4-[(2S)-2-phenylpropoxy]pyridin-1(2H)-yl}ethyl {[(3P)-3-(1H-imidazol-4-yl)phenyl]methyl}carbamate, H9 Immunoglobulin Light Chain, PHOSPHATE ION
Authors:Lederberg, O.L, Yan, N.L, Stanfield, R.L, Wilson, I.A, Kelly, J.W.
Deposit date:2024-03-05
Release date:2024-12-18
Last modified:2024-12-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of Potent and Selective Pyridone-Based Small Molecule Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains.
J.Med.Chem., 67, 2024
8FWE
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BU of 8fwe by Molmil
Neck structure of Agrobacterium phage Milano, C3 symmetry
Descriptor: Collar sheath protein, gp13, Neck 1 protein, ...
Authors:Sonani, R.R, Wang, F, Esteves, N.C, Kelly, R.J, Sebastian, A, Kreutzberger, M.A.B, Leiman, P.G, Scharf, B.E, Egelman, E.H.
Deposit date:2023-01-21
Release date:2023-12-06
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Neck and capsid architecture of the robust Agrobacterium phage Milano.
Commun Biol, 6, 2023
8XQU
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BU of 8xqu by Molmil
The Crystal Structure of ClpC1-NTD from Biortus.
Descriptor: 1,2-ETHANEDIOL, ATP-dependent Clp protease ATP-binding subunit ClpC1, DI(HYDROXYETHYL)ETHER, ...
Authors:Wang, F, Cheng, W, Lv, Z, Ju, C, Ni, C.
Deposit date:2024-01-05
Release date:2024-03-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The Crystal Structure of ClpC1-NTD from Biortus.
To Be Published
8DYS
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BU of 8dys by Molmil
Crystal structure of human Eukaryotic translation initiation factor 2A (eIF2A)
Descriptor: 1,2-ETHANEDIOL, Eukaryotic translation initiation factor 2A, GLYCEROL, ...
Authors:Righetto, G.L, Zeng, H, Dong, A, Li, Y, Hutchinson, A, Seitova, A, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC)
Deposit date:2022-08-05
Release date:2022-08-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of human Eukaryotic translation initiation factor 2A (eIF2A)
To Be Published
8G1T
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BU of 8g1t by Molmil
Crystal structure of Bax core domain BH3-groove dimer - tetrameric fraction P21
Descriptor: 1,2-ETHANEDIOL, Apoptosis regulator BAX
Authors:Cowan, A.D, Colman, P.M, Czabotar, P.E, Miller, M.S.
Deposit date:2023-02-02
Release date:2023-12-27
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.092 Å)
Cite:Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids.
Febs J., 291, 2024

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