1F93
CRYSTAL STRUCTURE OF A COMPLEX BETWEEN THE DIMERIZATION DOMAIN OF HNF-1 ALPHA AND THE COACTIVATOR DCOH
Summary for 1F93
Entry DOI | 10.2210/pdb1f93/pdb |
Descriptor | DIMERIZATION COFACTOR OF HEPATOCYTE NUCLEAR FACTOR 1-ALPHA, HEPATOCYTE NUCLEAR FACTOR 1-ALPHA (3 entities in total) |
Functional Keywords | four-helix bundle, transcriptional activator-coactivator complex, dimerization domain, transcription |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Cytoplasm: P61459 Nucleus: P22361 |
Total number of polymer chains | 8 |
Total formula weight | 62180.96 |
Authors | Rose, R.B.,Bayle, J.H.,Endrizzi, J.A.,Cronk, J.D.,Crabtree, G.R.,Alber, T. (deposition date: 2000-07-06, release date: 2000-09-20, Last modification date: 2011-07-13) |
Primary citation | Rose, R.B.,Bayle, J.H.,Endrizzi, J.A.,Cronk, J.D.,Crabtree, G.R.,Alber, T. Structural basis of dimerization, coactivator recognition and MODY3 mutations in HNF-1alpha. Nat.Struct.Biol., 7:744-748, 2000 Cited by PubMed: 10966642DOI: 10.1038/78966 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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