6JEH
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7VVY
| TRA module of NuA4 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ... | Authors: | Chen, Z, Qu, K. | Deposit date: | 2021-11-09 | Release date: | 2022-08-10 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of the NuA4 acetyltransferase complex bound to the nucleosome. Nature, 610, 2022
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7VVZ
| NuA4 bound to the nucleosome | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ... | Authors: | Qu, K, Chen, Z. | Deposit date: | 2021-11-09 | Release date: | 2022-08-10 | Last modified: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (8.8 Å) | Cite: | Structure of the NuA4 acetyltransferase complex bound to the nucleosome. Nature, 610, 2022
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6JEG
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6JCO
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1ST6
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8JJS
| Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP10343 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAA-ILE-SAR-SAR-7T2-SAR-IAE-LEU-MEA-MLE-7TK, ... | Authors: | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | Deposit date: | 2023-05-31 | Release date: | 2023-07-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.534 Å) | Cite: | Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor. J.Am.Chem.Soc., 145, 2023
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1JHW
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6YCX
| Plasmodium falciparum Myosin A full-length, pre-powerstroke state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin A tail domain interacting protein, ... | Authors: | Moussaoui, D, Robblee, J.P, Auguin, D, Krementsova, E.B, Robert-Paganin, J, Trybus, K.M, Houdusse, A. | Deposit date: | 2020-03-19 | Release date: | 2020-11-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.99 Å) | Cite: | Full-length Plasmodium falciparum myosin A and essential light chain PfELC structures provide new anti-malarial targets. Elife, 9, 2020
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1CEE
| SOLUTION STRUCTURE OF CDC42 IN COMPLEX WITH THE GTPASE BINDING DOMAIN OF WASP | Descriptor: | GTP-BINDING RHO-LIKE PROTEIN, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | Authors: | Abdul-Manan, N, Aghazadeh, B, Liu, G.A, Majumdar, A, Ouerfelli, O, Rosen, M.K. | Deposit date: | 1999-03-08 | Release date: | 1999-06-30 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein. Nature, 399, 1999
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6YCZ
| Plasmodium falciparum Myosin A delta-Nter, Post-Rigor state | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Moussaoui, D, Robblee, J.P, Auguin, D, Krementsova, E.B, Robert-Paganin, J, Trybus, K.M, Houdusse, A. | Deposit date: | 2020-03-19 | Release date: | 2020-11-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.27 Å) | Cite: | Full-length Plasmodium falciparum myosin A and essential light chain PfELC structures provide new anti-malarial targets. Elife, 9, 2020
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7LWH
| Human neurofibromin 2/merlin residues 1-339 in complex with LATS1 | Descriptor: | GLYCEROL, IMIDAZOLE, Merlin, ... | Authors: | Primi, M.C, Rangarajan, E.S, Izard, T. | Deposit date: | 2021-03-01 | Release date: | 2021-08-11 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.606 Å) | Cite: | Conformational flexibility determines the Nf2/merlin tumor suppressor functions. Matrix Biol Plus, 12, 2021
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3EG5
| Crystal structure of MDIA1-TSH GBD-FH3 in complex with CDC42-GMPPNP | Descriptor: | Cell division control protein 42 homolog, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Lammers, M, Meyer, S, Kuehlmann, D, Wittinghofer, A. | Deposit date: | 2008-09-10 | Release date: | 2008-10-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Specificity of Interactions between mDia Isoforms and Rho Proteins J.Biol.Chem., 283, 2008
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5GJK
| Crystal Structure of BAF47 and BAF155 Complex | Descriptor: | GLYCEROL, PHOSPHATE ION, SWI/SNF complex subunit SMARCC1, ... | Authors: | Yan, L, Qian, C. | Deposit date: | 2016-06-30 | Release date: | 2017-06-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.052 Å) | Cite: | Structural Insights into BAF47 and BAF155 Complex Formation. J. Mol. Biol., 429, 2017
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5LEF
| Rab6A:Kif20A complex | Descriptor: | GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ISOPROPYL ALCOHOL, ... | Authors: | Bressanelli, G, Pylypenko, O, Houdusse, A. | Deposit date: | 2016-06-29 | Release date: | 2017-11-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.088 Å) | Cite: | Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions. Nat Commun, 8, 2017
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4XH9
| CRYSTAL STRUCTURE OF HUMAN RHOA IN COMPLEX WITH DH/PH FRAGMENT OF THE GUANINE NUCLEOTIDE EXCHANGE FACTOR NET1 | Descriptor: | Neuroepithelial cell-transforming gene 1 protein, Transforming protein RhoA | Authors: | Garcia, C, Petit, P, Boutin, J.A, Ferry, G, Vuillard, L. | Deposit date: | 2015-01-05 | Release date: | 2015-01-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A structural study of the complex between neuroepithelial cell transforming gene 1 (Net1) and RhoA reveals a potential anticancer drug hot spot. J. Biol. Chem., 293, 2018
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3D9Y
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3DAV
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5FR2
| Farnesylated RhoA-GDP in complex with RhoGDI-alpha, lysine acetylated at K178 | Descriptor: | FARNESYL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Kuhlmann, N, Wroblowski, S, Knyphausen, P, de Boor, S, Brenig, J, Zienert, A.Y, Meyer-Teschendorf, K, Praefcke, G.J.K, Nolte, H, Krueger, M, Schacherl, M, Baumann, U, James, L.C, Chin, J.W, Lammers, M. | Deposit date: | 2015-12-15 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Structural and Mechanistic Insights Into the Regulation of the Fundamental Rho-Regulator Rhogdi Alpha by Lysine Acetylation. J.Biol.Chem., 291, 2016
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2VTG
| Crystal Structure of Human Iba2, trigonal crystal form | Descriptor: | ACETATE ION, IONIZED CALCIUM-BINDING ADAPTER MOLECULE 2, ZINC ION | Authors: | Schulze, J.O, Quedenau, C, Roske, Y, Turnbull, A, Mueller, U, Heinemann, U, Buessow, K. | Deposit date: | 2008-05-15 | Release date: | 2009-07-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural and Functional Characterization of Human Iba Proteins. FEBS J., 275, 2008
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3THF
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7B1A
| Myosin-II-AA mutant motor domain | Descriptor: | 1,2-ETHANEDIOL, ADP METAVANADATE, MAGNESIUM ION, ... | Authors: | Ewert, W, Preller, M. | Deposit date: | 2020-11-24 | Release date: | 2021-01-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Unraveling a Force-Generating Allosteric Pathway of Actomyosin Communication Associated with ADP and P i Release. Int J Mol Sci, 22, 2020
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7B19
| Mutant Myosin-II-GGG motor domain | Descriptor: | ADP METAVANADATE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Ewert, W, Preller, M. | Deposit date: | 2020-11-24 | Release date: | 2021-01-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Unraveling a Force-Generating Allosteric Pathway of Actomyosin Communication Associated with ADP and P i Release. Int J Mol Sci, 22, 2020
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1Y2O
| Structure of N-terminal domain IRSp53/BAIAP2 | Descriptor: | BAI1-associated protein 2 isoform 1 | Authors: | Millard, T.H, Bompard, G, Heung, M.-Y, Dafforn, T.R, Scott, D.J, Machesky, L.M, Futterer, K. | Deposit date: | 2004-11-23 | Release date: | 2005-02-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53 Embo J., 24, 2005
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7RTX
| Actophorin grown in microgravity | Descriptor: | Actophorin | Authors: | Lieberman, R.L, Quirk, S. | Deposit date: | 2021-08-16 | Release date: | 2021-12-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Improved resolution crystal structure of Acanthamoeba actophorin reveals structural plasticity not induced by microgravity. Acta Crystallogr.,Sect.F, 77, 2021
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