5FR2

Farnesylated RhoA-GDP in complex with RhoGDI-alpha, lysine acetylated at K178

Summary for 5FR2

• Entry DOI: 10.2210/pdb5fr2/pdb
• Related: 5FR1
• Descriptor: TRANSFORMING PROTEIN RHOA, RHO GDP-DISSOCIATION INHIBITOR 1, FARNESYL, ... (7 entities in total)
• Functional Keywords: signaling protein, lysine-acetylation, rhoa, ras-superfamily, rhogdi, cytoskeleton, gdp
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 2
• Total formula weight: 47461.04

Authors

Kuhlmann, N.,Wroblowski, S.,Knyphausen, P.,de Boor, S.,Brenig, J.,Zienert, A.Y.,Meyer-Teschendorf, K.,Praefcke, G.J.K.,Nolte, H.,Krueger, M.,Schacherl, M.,Baumann, U.,James, L.C.,Chin, J.W.,Lammers, M. (deposition date: 2015-12-15, release date: 2016-01-13, Last modification date: 2024-01-10)

• Primary citation: Kuhlmann, N.,Wroblowski, S.,Knyphausen, P.,De Boor, S.,Brenig, J.,Zienert, A.Y.,Meyer-Teschendorf, K.,Praefcke, G.J.K.,Nolte, H.,Kruger, M.,Schacherl, M.,Baumann, U.,James, L.C.,Chin, J.W.,Lammers, M.; Structural and Mechanistic Insights Into the Regulation of the Fundamental Rho-Regulator Rhogdi Alpha by Lysine Acetylation.; J.Biol.Chem., 291:5484-, 2016; PubMed: 26719334; DOI: 10.1074/JBC.M115.707091

Experimental method

X-RAY DIFFRACTION (3.35 Å)