5FR2

Farnesylated RhoA-GDP in complex with RhoGDI-alpha, lysine acetylated at K178

Summary for 5FR2

Related5FR1
DescriptorTRANSFORMING PROTEIN RHOA, RHO GDP-DISSOCIATION INHIBITOR 1, FARNESYL, ... (7 entities in total)
Functional Keywordssignaling protein, lysine-acetylation, rhoa, ras-superfamily, rhogdi, cytoskeleton, gdp
Biological sourceHOMO SAPIENS (HUMAN)
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Total number of polymer chains2
Total molecular weight47461.04
Authors
Primary citation
Kuhlmann, N.,Wroblowski, S.,Knyphausen, P.,De Boor, S.,Brenig, J.,Zienert, A.Y.,Meyer-Teschendorf, K.,Praefcke, G.J.K.,Nolte, H.,Kruger, M.,Schacherl, M.,Baumann, U.,James, L.C.,Chin, J.W.,Lammers, M.
Structural and Mechanistic Insights Into the Regulation of the Fundamental Rho-Regulator Rhogdi Alpha by Lysine Acetylation.
J.Biol.Chem., 291:5484-, 2016
PubMed: 26719334 (PDB entries with the same primary citation)
DOI: 10.1074/JBC.M115.707091
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.35 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26940 0.6% 1.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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171916
PDB entries from 2020-12-02