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1W80
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BU of 1w80 by Molmil
Crystal structure of the alpha-adaptin appendage domain, from the AP2 adaptor complex, bound to 2 peptides from Synaptojanin170
Descriptor: ADAPTER-RELATED PROTEIN COMPLEX 2 ALPHA 2 SUBUNIT, BENZAMIDINE, CARBONATE ION, ...
Authors:Ford, M.G.J, Praefcke, G.J.K, McMahon, H.T.
Deposit date:2004-09-14
Release date:2004-10-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Evolving Nature of the Ap2 Alpha-Appendage Hub During Clathrin-Coated Vesicle Endocytosis.
Embo J., 23, 2004
2VJ0
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BU of 2vj0 by Molmil
Crystal structure of the alpha-adaptin appendage domain, from the AP2 adaptor complex, in complex with an FXDNF peptide from amphiphysin1 and a WVXF peptide from synaptojanin P170
Descriptor: AMPHIPHYSIN, AP-2 COMPLEX SUBUNIT ALPHA-2, BENZAMIDINE, ...
Authors:Ford, M.G.J, Praefcke, G.J.K, McMahon, H.T.
Deposit date:2007-12-06
Release date:2007-12-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Solitary and Repetitive Binding Motifs for the Ap2 Complex {Alpha}-Appendage in Amphiphysin and Other Accessory Proteins.
J.Biol.Chem., 283, 2008
1OM9
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BU of 1om9 by Molmil
Structure of the GGA1-appendage in complex with the p56 binding peptide
Descriptor: 15-mer peptide fragment of p56, ADP-ribosylation factor binding protein GGA1
Authors:Collins, B.M, Praefcke, G.J.K, Robinson, M.S, Owen, D.J.
Deposit date:2003-02-25
Release date:2003-07-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for binding of accessory proteins by the appendage domain of GGAs
Nat.Struct.Biol., 10, 2003
5FR2
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BU of 5fr2 by Molmil
Farnesylated RhoA-GDP in complex with RhoGDI-alpha, lysine acetylated at K178
Descriptor: FARNESYL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kuhlmann, N, Wroblowski, S, Knyphausen, P, de Boor, S, Brenig, J, Zienert, A.Y, Meyer-Teschendorf, K, Praefcke, G.J.K, Nolte, H, Krueger, M, Schacherl, M, Baumann, U, James, L.C, Chin, J.W, Lammers, M.
Deposit date:2015-12-15
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Structural and Mechanistic Insights Into the Regulation of the Fundamental Rho-Regulator Rhogdi Alpha by Lysine Acetylation.
J.Biol.Chem., 291, 2016
1F5N
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BU of 1f5n by Molmil
HUMAN GUANYLATE BINDING PROTEIN-1 IN COMPLEX WITH THE GTP ANALOGUE, GMPPNP.
Descriptor: INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Prakash, B, Renault, L, Praefcke, G.J.K, Herrmann, C, Wittinghofer, A.
Deposit date:2000-06-15
Release date:2000-09-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism.
EMBO J., 19, 2000
1DG3
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BU of 1dg3 by Molmil
STRUCTURE OF HUMAN GUANYLATE BINDING PROTEIN-1 IN NUCLEOTIDE FREE FORM
Descriptor: PROTEIN (INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1)
Authors:Prakash, B, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C.
Deposit date:1999-11-23
Release date:2000-10-11
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins.
Nature, 403, 2000
4BKG
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BU of 4bkg by Molmil
crystal structure of human diSUMO-2
Descriptor: SMALL UBIQUITIN-RELATED MODIFIER 2
Authors:Keusekotten, K, Bade, V.N, Meyer-Teschendorf, K, Sriramachandran, A, Fischer-Schrader, K, Krause, A, Horst, C, Hofmann, K, Dohmen, R.J, Praefcke, G.J.K.
Deposit date:2013-04-25
Release date:2013-11-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Multivalent Interactions of the Sumo-Interaction Motifs in the Ring-Finger Protein 4 (Rnf4) Determine the Specificity for Chains of the Small Ubiquitin-Related Modifier (Sumo).
Biochem.J., 457, 2014
2IV9
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BU of 2iv9 by Molmil
B2-appendage from AP2 in complex with Eps15 peptide
Descriptor: AP-2 COMPLEX SUBUNIT BETA-2, EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE 15 ISOFORM B, SULFATE ION
Authors:Ford, M.G.J, Schmid, E.M, McMahon, H.T.
Deposit date:2006-06-08
Release date:2007-03-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Role of the Ap2 Beta-Appendage Hub in Recruiting Partners for Clathrin-Coated Vesicle Assembly
Plos Biol., 4, 2006
2IV8
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BU of 2iv8 by Molmil
beta appendage in complex with b-arrestin peptide
Descriptor: AP-2 COMPLEX SUBUNIT BETA-1, BETA-ARRESTIN-1
Authors:Ford, M.G.J, Schmid, E.M, McMahon, H.T.
Deposit date:2006-06-08
Release date:2007-06-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Role of the Ap2 Beta-Appendage Hub in Recruiting Partners for Clathrin-Coated Vesicle Assembly.
Plos Biol., 4, 2006
2B8W
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BU of 2b8w by Molmil
Crystal-structure of the N-terminal Large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with GMP/AlF4
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, Interferon-induced guanylate-binding protein 1, MAGNESIUM ION, ...
Authors:Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C.
Deposit date:2005-10-10
Release date:2006-03-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
2B92
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BU of 2b92 by Molmil
Crystal-structure of the N-terminal Large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with GDP/AlF3
Descriptor: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Interferon-induced guanylate-binding protein 1, ...
Authors:Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C.
Deposit date:2005-10-10
Release date:2006-03-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
2BC9
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BU of 2bc9 by Molmil
Crystal-structure of the N-terminal large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with non-hydrolysable GTP analogue GppNHp
Descriptor: Interferon-induced guanylate-binding protein 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C.
Deposit date:2005-10-19
Release date:2006-03-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
2D4H
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BU of 2d4h by Molmil
Crystal-structure of the N-terminal large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with GMP
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, Interferon-induced guanylate-binding protein 1
Authors:Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C.
Deposit date:2005-10-19
Release date:2006-03-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
1TQ2
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BU of 1tq2 by Molmil
Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E.
Deposit date:2004-06-16
Release date:2004-09-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases
Mol.Cell, 15, 2004
1TQ6
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BU of 1tq6 by Molmil
Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, interferon-inducible GTPase
Authors:Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E.
Deposit date:2004-06-16
Release date:2004-09-21
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases
Mol.Cell, 15, 2004
1TQD
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BU of 1tqd by Molmil
Crystal structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, interferon-inducible GTPase
Authors:Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E.
Deposit date:2004-06-17
Release date:2004-09-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases
Mol.Cell, 15, 2004
1TQ4
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BU of 1tq4 by Molmil
Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, interferon-inducible GTPase
Authors:Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E.
Deposit date:2004-06-16
Release date:2004-09-21
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases
Mol.Cell, 15, 2004
1TPZ
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BU of 1tpz by Molmil
Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E.
Deposit date:2004-06-16
Release date:2004-09-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases
Mol.Cell, 15, 2004

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