1CEE

SOLUTION STRUCTURE OF CDC42 IN COMPLEX WITH THE GTPASE BINDING DOMAIN OF WASP

Summary for 1CEE

DescriptorGTP-BINDING RHO-LIKE PROTEIN, WISKOTT-ALDRICH SYNDROME PROTEIN WASP, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordscdc42 actin regulator gtpase and the gtpase binding domain of its effector wasp, structural protein regulation
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Lipid-anchor; Cytoplasmic side (Potential) P60953
Cytoplasm, cytoskeleton P42768
Total number of polymer chains2
Total molecular weight26809.4
Authors
Abdul-Manan, N.,Aghazadeh, B.,Liu, G.A.,Majumdar, A.,Ouerfelli, O.,Rosen, M.K. (deposition date: 1999-03-08, release date: 1999-06-30, Last modification date: 2011-07-13)
Primary citation
Abdul-Manan, N.,Aghazadeh, B.,Liu, G.A.,Majumdar, A.,Ouerfelli, O.,Siminovitch, K.A.,Rosen, M.K.
Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein.
Nature, 399:379-383, 1999
PubMed: 10360578 (PDB entries with the same primary citation)
DOI: 10.1038/20726
MImport into Mendeley
Experimental method
SOLUTION NMR
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers314.6%20.9%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation reportDownload