8FOR
| |
8TFX
| tRNA 2'-phosphotransferase (Tpt1) from Pyrococcus horikoshii in complex with 2',5'-ADP | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-2'-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Jacewicz, A, Dantuluri, S, Shuman, S. | Deposit date: | 2023-07-12 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
6F4P
| Human JMJD5 in complex with MN, NOG and RPS6 (129-144) (complex-1) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 40S ribosomal protein S6, JmjC domain-containing protein 5, ... | Authors: | Chowdhury, R, Islam, M.S, Schofield, C.J. | Deposit date: | 2017-11-29 | Release date: | 2018-04-04 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | JMJD5 is a human arginyl C-3 hydroxylase. Nat Commun, 9, 2018
|
|
6F6T
| |
4LE0
| Crystal structure of the receiver domain of DesR in complex with beryllofluoride and magnesium | Descriptor: | ACETATE ION, BERYLLIUM TRIFLUORIDE ION, GLYCEROL, ... | Authors: | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | Deposit date: | 2013-06-25 | Release date: | 2014-07-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation. MBio, 5, 2014
|
|
7OR4
| Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, B142 | Descriptor: | Dipeptidyl peptidase 8, methyl 3-[4-[(4-bromophenyl)methyl]piperazin-1-yl]carbonyl-5-[(2-ethyl-2-methanoyl-butanoyl)amino]benzoate, trimethylamine oxide | Authors: | Ross, B, Huber, R. | Deposit date: | 2021-06-04 | Release date: | 2021-07-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9. Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
8TFY
| |
7OLE
| Cryo-EM structure of the TELO2-TTI1-TTI2-RUVBL1-RUVBL2 complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2, ... | Authors: | Pal, M, Llorca, O, Pearl, L. | Deposit date: | 2021-05-19 | Release date: | 2021-07-07 | Last modified: | 2021-10-06 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone. Cell Rep, 36, 2021
|
|
7OZ7
| Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, L84 | Descriptor: | Dipeptidyl peptidase 8, trimethylamine oxide, ~{N}-[3-[[4-[(4-bromophenyl)methyl]piperazin-1-yl]methyl]phenyl]-2-ethyl-2-methanoyl-butanamide | Authors: | Ross, B, Huber, R. | Deposit date: | 2021-06-26 | Release date: | 2021-07-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9. Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
6F6B
| |
7OW0
| |
7OXS
| |
8FTA
| |
6F9K
| |
4LIW
| |
6F8L
| |
8FO9
| |
7ORF
| Crystal structure of JNK3 in complex with FMU-001-367 (compound 1) | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Mitogen-activated protein kinase 10, ... | Authors: | Chaikuad, A, Koch, P, Laufer, S, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2021-06-05 | Release date: | 2021-07-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Controlling the Covalent Reactivity of a Kinase Inhibitor with Light. Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
8TRG
| |
4LO0
| Apo HA17-HA33 | Descriptor: | HA-17, HA-33 | Authors: | Lee, K, Gu, S, Jin, L, Le, T.T, Cheng, L.W, Strotmeier, J, Kruel, A.M, Yao, G, Perry, K, Rummel, A, Jin, R. | Deposit date: | 2013-07-12 | Release date: | 2013-10-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.055 Å) | Cite: | Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity. Plos Pathog., 9, 2013
|
|
8TNS
| |
4LAP
| |
7P18
| Crystal structure of 3-ketosteroid delta1-dehydrogenase from Sterolibacterium denitrificans in complex with 1,4-androstadiene-3,17-dione | Descriptor: | 3-oxosteroid 1-dehydrogenase, ANDROSTA-1,4-DIENE-3,17-DIONE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Wojcik, P, Mrugala, B, Kurpiewska, K, Szaleniec, M. | Deposit date: | 2021-07-01 | Release date: | 2021-07-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structure, Mutagenesis, and QM:MM Modeling of 3-Ketosteroid Delta 1 -Dehydrogenase from Sterolibacterium denitrificans ─The Role of a New Putative Membrane-Associated Domain and Proton-Relay System in Catalysis. Biochemistry, 62, 2023
|
|
4LNF
| B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of GS-Q | Descriptor: | GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ... | Authors: | Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L. | Deposit date: | 2013-07-11 | Release date: | 2013-11-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.949 Å) | Cite: | Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism. J.Biol.Chem., 288, 2013
|
|
7P7X
| Crystal structure of D-amino acid transaminase from Haliscomenobacter hydrossis (holo form). | Descriptor: | ACETATE ION, Aminotransferase class IV, PHOSPHATE ION, ... | Authors: | Boyko, K.M, Nikolaeva, A.Y, Bakunova, A.K, Rakitina, T.V, Bezsudnova, E.Y, Popov, V.O. | Deposit date: | 2021-07-20 | Release date: | 2021-07-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Uncommon Active Site of D-Amino Acid Transaminase from Haliscomenobacter hydrossis : Biochemical and Structural Insights into the New Enzyme. Molecules, 26, 2021
|
|