8TFX

tRNA 2'-phosphotransferase (Tpt1) from Pyrococcus horikoshii in complex with 2',5'-ADP

Summary for 8TFX

• Entry DOI: 10.2210/pdb8tfx/pdb
• Related: 8TFI
• Descriptor: Probable RNA 2'-phosphotransferase, ADENOSINE-2'-5'-DIPHOSPHATE, 1,2-ETHANEDIOL, ... (7 entities in total)
• Functional Keywords: trna 2'-phosphotransferase, tpt1, trna splicing, 2', 5'-adp, transferase
• Biological source: Pyrococcus horikoshii OT3
• Total number of polymer chains: 1
• Total formula weight: 22036.41

Authors

Jacewicz, A.,Dantuluri, S.,Shuman, S. (deposition date: 2023-07-12, release date: 2023-11-08)

• Primary citation: Jacewicz, A.,Dantuluri, S.,Shuman, S.; Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD.; Proc.Natl.Acad.Sci.USA, 120:e2312999120-e2312999120, 2023; PubMed: 37883434; DOI: 10.1073/pnas.2312999120

Experimental method

X-RAY DIFFRACTION (1.7 Å)