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6NUH
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BU of 6nuh by Molmil
Non-covalent DNA-protein complex between E. coli YedK and ssDNA containing an abasic site analog
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(*GP*TP*CP*(PDI)P*GP*GP*A)-3'), SOS response-associated peptidase YedK
Authors:Eichman, B.F, Amidon, K.M.
Deposit date:2019-02-01
Release date:2019-06-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.594 Å)
Cite:Protection of abasic sites during DNA replication by a stable thiazolidine protein-DNA cross-link.
Nat.Struct.Mol.Biol., 26, 2019
1URJ
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BU of 1urj by Molmil
Single stranded DNA-binding protein(ICP8) from Herpes simplex virus-1
Descriptor: MAJOR DNA-BINDING PROTEIN, MERCURY (II) ION, ZINC ION
Authors:Panjikar, S, Mapelli, M, Tucker, P.A.
Deposit date:2003-10-30
Release date:2004-11-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of the herpes simplex virus 1 ssDNA-binding protein suggests the structural basis for flexible, cooperative single-stranded DNA binding.
J. Biol. Chem., 280, 2005
6LMJ
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ASFV pA104R in complex with double-strand DNA
Descriptor: A104R, DNA (5'-D(*TP*GP*CP*TP*TP*AP*TP*CP*AP*AP*TP*TP*TP*GP*TP*TP*GP*CP*A)-3')
Authors:Wang, H, Qi, J, Chai, Y, Gao, F, Liu, R.
Deposit date:2019-12-25
Release date:2020-05-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structural basis of African swine fever virus pA104R binding to DNA and its inhibition by stilbene derivatives.
Proc.Natl.Acad.Sci.USA, 117, 2020
3SWP
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BU of 3swp by Molmil
ANAC019 NAC domain in complex with DNA
Descriptor: NAC domain-containing protein 19, oligonucleotide forward, oligonucleotide reverse
Authors:Welner, D, Lo Leggio, L.
Deposit date:2011-07-14
Release date:2012-04-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4.113 Å)
Cite:DNA binding by the plant-specific NAC transcription factors in crystal and solution: a firm link to WRKY and GCM transcription factors.
Biochem.J., 444, 2012
6YMG
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BU of 6ymg by Molmil
VcaM4I restriction endonuclease in complex with 5mC-modified dsDNA
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*A)-3'), DNA (5'-D(P*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3'), ...
Authors:Pastor, M, Czapinska, H, Lutz, T, Helbrecht, I, Xu, S, Bochtler, M.
Deposit date:2020-04-08
Release date:2020-12-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Crystal structures of the EVE-HNH endonuclease VcaM4I in the presence and absence of DNA.
Nucleic Acids Res., 49, 2021
3SWM
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BU of 3swm by Molmil
The NAC domain of ANAC019 in complex with DNA, gold derivative
Descriptor: GOLD ION, NAC domain-containing protein 19, oligonucleotide forward, ...
Authors:Welner, D, Lo Leggio, L.
Deposit date:2011-07-14
Release date:2012-04-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4.25 Å)
Cite:DNA binding by the plant-specific NAC transcription factors in crystal and solution: a firm link to WRKY and GCM transcription factors.
Biochem.J., 444, 2012
6YJB
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BU of 6yjb by Molmil
VcaM4I restriction endonuclease 5hmC-ssDNA complex
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*AP*(5HC)P*AP*G)-3'), GLYCEROL, ...
Authors:Pastor, M, Czapinska, H, Lutz, T, Helbrecht, I, Xu, S, Bochtler, M.
Deposit date:2020-04-02
Release date:2020-12-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures of the EVE-HNH endonuclease VcaM4I in the presence and absence of DNA.
Nucleic Acids Res., 49, 2021
8B9B
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BU of 8b9b by Molmil
S. cerevisiae replisome + Ctf4, bound by pol alpha. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand.
Descriptor: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ...
Authors:Jones, M.L, Yeeles, J.T.P.
Deposit date:2022-10-05
Release date:2023-08-09
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
8B9A
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BU of 8b9a by Molmil
S. cerevisiae replisome + Ctf4, bound by pol alpha primase. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand.
Descriptor: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ...
Authors:Jones, M.L, Yeeles, J.T.P.
Deposit date:2022-10-05
Release date:2023-08-09
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
6DSW
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BU of 6dsw by Molmil
Bst DNA polymerase I pre-chemistry (n) structure
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*G)-3'), DNA (5'-D(P*AP*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ...
Authors:Chim, N, Jackson, L.N, Chaput, J.C.
Deposit date:2018-06-14
Release date:2018-10-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.589 Å)
Cite:Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway.
Elife, 7, 2018
6OEB
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BU of 6oeb by Molmil
Crystal structure of HMCES SRAP domain in complex with 3' overhang DNA
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*CP*AP*GP*AP*CP*GP*TP*T)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*G)-3'), ...
Authors:Halabelian, L, Ravichandran, M, Li, Y, Zeng, H, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
Deposit date:2019-03-27
Release date:2019-04-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition.
Nat.Struct.Mol.Biol., 26, 2019
6DSU
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BU of 6dsu by Molmil
Bst DNA polymerase I pre-insertion complex structure
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ...
Authors:Chim, N, Jackson, L.N, Chaput, J.C.
Deposit date:2018-06-14
Release date:2018-10-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway.
Elife, 7, 2018
5BUA
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BU of 5bua by Molmil
Lysine 120-acetylated P53 DNA binding domain in a complex with DNA.
Descriptor: Cellular tumor antigen p53, DNA (5'-D(P*GP*GP*AP*CP*AP*TP*GP*TP*CP*C)-3'), ZINC ION
Authors:Arbely, E, Vainer, R.
Deposit date:2015-06-03
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.812 Å)
Cite:Structural Basis for p53 Lys120-Acetylation-Dependent DNA-Binding Mode.
J.Mol.Biol., 428, 2016
3C2L
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BU of 3c2l by Molmil
Ternary complex of DNA POLYMERASE BETA with a C:DAPCPP mismatch in the active site
Descriptor: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine, DNA (5'-D(*DCP*DCP*DGP*DAP*DCP*DCP*DGP*DCP*DGP*DCP*DAP*DTP*DCP*DAP*DGP*DC)-3'), DNA (5'-D(*DGP*DCP*DTP*DGP*DAP*DTP*DGP*DCP*DGP*DC)-3'), ...
Authors:Batra, V.K, Beard, W.A, Shock, D.D, Pedersen, L.C, Wilson, S.H.
Deposit date:2008-01-25
Release date:2008-05-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of DNA polymerase beta with active-site mismatches suggest a transient abasic site intermediate during misincorporation.
Mol.Cell, 30, 2008
6YKF
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BU of 6ykf by Molmil
VcaM4I restriction endonuclease in the presence of 5mC-modified ssDNA
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*AP*(5CM)P*AP*G)-3'), GLYCEROL, ...
Authors:Pastor, M, Czapinska, H, Lutz, T, Helbrecht, I, Xu, S, Bochtler, M.
Deposit date:2020-04-06
Release date:2020-12-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Crystal structures of the EVE-HNH endonuclease VcaM4I in the presence and absence of DNA.
Nucleic Acids Res., 49, 2021
7W1M
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BU of 7w1m by Molmil
Cryo-EM structure of human cohesin-CTCF-DNA complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cohesin subunit SA-1, ...
Authors:Shi, Z.B, Bai, X.C, Yu, H.
Deposit date:2021-11-19
Release date:2023-05-31
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:CTCF and R-loops are boundaries of cohesin-mediated DNA looping.
Mol.Cell, 83, 2023
3C2M
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BU of 3c2m by Molmil
Ternary complex of DNA POLYMERASE BETA with a G:dAPCPP mismatch in the active site
Descriptor: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine, DNA (5'-D(*DCP*DCP*DGP*DAP*DCP*DGP*DGP*DCP*DGP*DCP*DAP*DTP*DCP*DAP*DGP*DC)-3'), ...
Authors:Batra, V.K, Beard, W.A, Shock, D.D, Pedersen, L.C, Wilson, S.H.
Deposit date:2008-01-25
Release date:2008-05-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structures of DNA polymerase beta with active-site mismatches suggest a transient abasic site intermediate during misincorporation.
Mol.Cell, 30, 2008
3JPP
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BU of 3jpp by Molmil
Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-MonoMethyl Methylene triphosphate
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy({(S)-hydroxy[(1R)-1-phosphonoethyl]phosphoryl}oxy)phosphoryl]guanosine, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ...
Authors:Batra, V.K, Upton, J, Kashmerov, B, Beard, W.A, Wilson, S.H, Goodman, M.F, McKenna, C.E.
Deposit date:2009-09-04
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues.
J.Am.Chem.Soc., 132, 2010
3JPT
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BU of 3jpt by Molmil
Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-fluoro chloro methylene triphosphate
Descriptor: 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
Authors:Batra, V.K, Upton, J, Kashmerov, B, Beard, W.A, Wilson, S.H, Goodman, M.F, McKenna, C.E.
Deposit date:2009-09-04
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues.
J.Am.Chem.Soc., 132, 2010
2W9C
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BU of 2w9c by Molmil
Ternary complex of Dpo4 bound to N2,N2-dimethyl-deoxyguanosine modified DNA with incoming dTTP
Descriptor: 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*DOCP)-3', 5'-D(*TP*CP*AP*CP*O2GP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', DNA POLYMERASE IV, ...
Authors:Eoff, R.L, Zhang, H, Kosekov, I.D, Rizzo, C.J, Egli, M, Guengerich, F.P.
Deposit date:2009-01-22
Release date:2009-05-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-Function Relationships in Miscoding by Sulfolobus Solfataricus DNA Polymerase Dpo4: Guanine N2,N2-Dimethyl Substitution Produces Inactive and Miscoding Polymerase Complexes.
J.Biol.Chem., 284, 2009
2W9A
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BU of 2w9a by Molmil
Ternary complex of Dpo4 bound to N2,N2-dimethyl-deoxyguanosine modified DNA with incoming dGTP
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*DOC)-3', 5'-D(*TP*CP*AP*CP*O2GP*GP*AP*AP*TP*CP *CP*TP*TP*CP*CP*CP*CP*C)-3', ...
Authors:Eoff, R.L, Zhang, H, Kosekov, I.D, Rizzo, C.J, Egli, M, Guengerich, F.P.
Deposit date:2009-01-22
Release date:2009-05-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-Function Relationships in Miscoding by Sulfolobus Solfataricus DNA Polymerase Dpo4: Guanine N2,N2-Dimethyl Substitution Produces Inactive and Miscoding Polymerase Complexes.
J.Biol.Chem., 284, 2009
2W9B
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BU of 2w9b by Molmil
Binary complex of Dpo4 bound to N2,N2-dimethyl-deoxyguanosine modified DNA
Descriptor: 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*DOCP)-3', 5'-D(*TP*CP*AP*TP*M2GP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', DNA POLYMERASE IV, ...
Authors:Eoff, R.L, Zhang, H, Kosekov, I.D, Rizzo, C.J, Egli, M, Guengerich, F.P.
Deposit date:2009-01-22
Release date:2009-05-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structure-Function Relationships in Miscoding by Sulfolobus Solfataricus DNA Polymerase Dpo4: Guanine N2,N2-Dimethyl Substitution Produces Inactive and Miscoding Polymerase Complexes.
J.Biol.Chem., 284, 2009
6Q4V
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BU of 6q4v by Molmil
KlenTaq DNA polymerase in complex with dATP
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*CP*TP*GP*TP*GP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ...
Authors:Kropp, H.M, Diederichs, K, Marx, A.
Deposit date:2018-12-06
Release date:2019-02-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:The Structure of an Archaeal B-Family DNA Polymerase in Complex with a Chemically Modified Nucleotide.
Angew.Chem.Int.Ed.Engl., 58, 2019
5KTQ
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BU of 5ktq by Molmil
LARGE FRAGMENT OF TAQ DNA POLYMERASE BOUND TO DCTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, PROTEIN (DNA POLYMERASE I)
Authors:Li, Y, Kong, Y, Korolev, S, Waksman, G.
Deposit date:1998-09-22
Release date:1998-09-30
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of the Klenow fragment of Thermus aquaticus DNA polymerase I complexed with deoxyribonucleoside triphosphates.
Protein Sci., 7, 1998
1WTV
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BU of 1wtv by Molmil
Hyperthermophile chromosomal protein SAC7D single mutant M29A in complex with DNA GTAATTAC
Descriptor: 5'-D(*GP*TP*AP*AP*TP*TP*AP*C)-3', DNA-binding proteins 7a/7b/7d
Authors:Chen, C.-Y, Ko, T.-P, Lin, T.-W, Chou, C.-C, Chen, C.-J, Wang, A.H.-J.
Deposit date:2004-11-29
Release date:2005-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d
NUCLEIC ACIDS RES., 33, 2005

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