8B9A

S. cerevisiae replisome + Ctf4, bound by pol alpha primase. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand.

This is a non-PDB format compatible entry.

Summary for 8B9A

• Entry DOI: 10.2210/pdb8b9a/pdb
• EMDB information: 15309
• Descriptor: DNA replication licensing factor MCM2, DNA replication complex GINS protein PSF2, DNA replication complex GINS protein PSF3, ... (24 entities in total)
• Functional Keywords: replication, helicase, polymerase, pol alpha, priming
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Total number of polymer chains: 23
• Total formula weight: 1843993.88

Authors

Jones, M.L.,Yeeles, J.T.P. (deposition date: 2022-10-05, release date: 2023-08-09, Last modification date: 2023-08-30)

• Primary citation: Jones, M.L.,Aria, V.,Baris, Y.,Yeeles, J.T.P.; How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.; Mol.Cell, 83:2911-, 2023; PubMed: 37506699; DOI: 10.1016/j.molcel.2023.06.035

Experimental method

ELECTRON MICROSCOPY (3.5 Å)