1XZ3
 
 | | Complex of apoferritin with isoflurane | | Descriptor: | 1-CHLORO-2,2,2-TRIFLUOROETHYL DIFLUOROMETHYL ETHER, CADMIUM ION, Ferritin light chain | | Authors: | Liu, R, Loll, P.J, Eckenhoff, R.G. | | Deposit date: | 2004-11-11 | | Release date: | 2005-05-10 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural basis for high-affinity volatile anesthetic binding in a natural 4-helix bundle protein.
Faseb J., 19, 2005
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1XZ1
 | | Complex of halothane with apoferritin | | Descriptor: | 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE, CADMIUM ION, Ferritin light chain | | Authors: | Liu, R, Loll, P.J, Eckenhoff, R.G. | | Deposit date: | 2004-11-11 | | Release date: | 2005-05-10 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural basis for high-affinity volatile anesthetic binding in a natural 4-helix bundle protein.
Faseb J., 19, 2005
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1QS9
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1QTD
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1QS5
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1QSB
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1QTH
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1QTC
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1QTB
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5YXI
 | | Designed protein dRafX6 | | Descriptor: | Designed protein dRafX6 | | Authors: | Liu, R. | | Deposit date: | 2017-12-05 | | Release date: | 2018-12-05 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | De novo sequence redesign of a functional Ras-binding domain globally inverted the surface charge distribution and led to extreme thermostability.
Biotechnol.Bioeng., 118, 2021
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7VSQ
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3NDP
 | | Crystal structure of human AK4(L171P) | | Descriptor: | Adenylate kinase isoenzyme 4, SULFATE ION | | Authors: | Liu, R, Wang, Y, Wei, Z, Gong, W. | | Deposit date: | 2010-06-07 | | Release date: | 2010-06-23 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of human adenylate kinase 4 (L171P) suggests the role of hinge region in protein domain motion
Biochem.Biophys.Res.Commun., 379, 2009
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3U90
 | | apoferritin: complex with SDS | | Descriptor: | CADMIUM ION, DODECYL SULFATE, Ferritin light chain | | Authors: | Liu, R, Bu, W, Xi, J, Mortazavi, S.R, Cheung-Lau, J.C, Dmochowski, I.J, Loll, P.J. | | Deposit date: | 2011-10-17 | | Release date: | 2012-04-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Beyond the detergent effect: a binding site for sodium dodecyl sulfate (SDS) in mammalian apoferritin.
Acta Crystallogr.,Sect.D, 68, 2012
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6LQE
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6LQF
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8ILX
 | | mCherry-LaM3 complex | | Descriptor: | LAM3, MCherry fluorescent protein | | Authors: | Liang, H, Liu, R, Ding, Y. | | Deposit date: | 2023-03-05 | | Release date: | 2023-06-21 | | Method: | X-RAY DIFFRACTION (3.29 Å) | | Cite: | Structural Insights into the Binding of Red Fluorescent Protein mCherry-Specific Nanobodies.
Int J Mol Sci, 24, 2023
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8IM1
 | | mCherry-LaM1 complex | | Descriptor: | LaM1, MCherry fluorescent protein, SULFATE ION | | Authors: | Liang, H, Liu, R, Ding, Y. | | Deposit date: | 2023-03-05 | | Release date: | 2023-06-21 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural Insights into the Binding of Red Fluorescent Protein mCherry-Specific Nanobodies.
Int J Mol Sci, 24, 2023
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8IM0
 | | mCherry-LaM8 complex | | Descriptor: | LaM8, MCherry fluorescent protein | | Authors: | Liang, H, Liu, R, Ding, Y. | | Deposit date: | 2023-03-05 | | Release date: | 2023-06-21 | | Method: | X-RAY DIFFRACTION (1.31 Å) | | Cite: | Structural Insights into the Binding of Red Fluorescent Protein mCherry-Specific Nanobodies.
Int J Mol Sci, 24, 2023
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8XN7
 | | Crystal structure of HPK1 kinase domain T165E,S171E phosphomimetic mutant in complex with compound 9f | | Descriptor: | 5-amino-2-((6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino)-8-(2-(trifluoromethyl)benzyl)pyrido[2,3-d]pyrimidin-7(8H)-one, Mitogen-activated protein kinase kinase kinase kinase 1 | | Authors: | Huang, W.X, Liu, R, Ding, K. | | Deposit date: | 2023-12-29 | | Release date: | 2024-04-10 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Discovery of 5-aminopyrido[2,3-d]pyrimidin-7(8H)-one derivatives as new hematopoietic progenitor kinase 1 (HPK1) inhibitors.
Eur.J.Med.Chem., 269, 2024
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4WOY
 | | Crystal structure and functional analysis of MiD49, a receptor for the mitochondrial fission protein Drp1 | | Descriptor: | Mitochondrial dynamics protein MID49 | | Authors: | Loson, O.C, Meng, S, Ngo, H.B, Liu, R, Kaiser, J.T, Chan, D.C. | | Deposit date: | 2014-10-17 | | Release date: | 2015-01-28 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure and functional analysis of MiD49, a receptor for the mitochondrial fission protein Drp1.
Protein Sci., 24, 2015
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4DE6
 | | Horse spleen apo-ferritin complex with arachidonic acid | | Descriptor: | ARACHIDONIC ACID, CADMIUM ION, Ferritin light chain, ... | | Authors: | Bu, W, Liu, R, Dmochowski, I.J, Loll, P.J, Eckenhoff, R.G. | | Deposit date: | 2012-01-19 | | Release date: | 2012-03-07 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Ferritin couples iron and fatty acid metabolism.
Faseb J., 26, 2012
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7ARO
 | | Crystal structure of the non-ribose partial agonist LUF5833 bound to the adenosine A2A receptor | | Descriptor: | 2-azanyl-6-(1~{H}-imidazol-2-ylmethylsulfanyl)-4-phenyl-pyridine-3,5-dicarbonitrile, Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, CHOLESTEROL, ... | | Authors: | Verdon, G, Amelia, T, van Veldhoven, J, Falsini, M, Liu, R, Heitman, L, van Westen, G, Segala, E, Cheng, R, Cooke, R, van der Es, D, Ijzerman, A. | | Deposit date: | 2020-10-25 | | Release date: | 2021-04-07 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.119 Å) | | Cite: | Crystal Structure and Subsequent Ligand Design of a Nonriboside Partial Agonist Bound to the Adenosine A 2A Receptor.
J.Med.Chem., 64, 2021
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8GZ3
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8HBE
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8HBF
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