1NY2
 
 | | Human alpha thrombin inhibited by RPPGF and hirugen | | Descriptor: | Hirugen, Inhibitor peptide RPPGF, thrombin Heavy chain, ... | | Authors: | Krishnan, R, Tulinsky, A, Schmaier, A.H, Hasan, A.A, Warnock, M, Srikanth, S, Mahdi, F. | | Deposit date: | 2003-02-11 | | Release date: | 2003-03-04 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Mechanisms of Arg-Pro-Pro-Gly-Phe inhibition of thrombin.
Am.J.Physiol.Heart Circ.Physiol., 285, 2003
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1P01
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1OKX
 | | Binding Structure of Elastase Inhibitor Scyptolin A | | Descriptor: | ELASTASE 1, SCYPTOLIN A | | Authors: | Matern, U, Schleberger, C, Jelakovic, S, Weckesser, J, Schulz, G.E. | | Deposit date: | 2003-07-31 | | Release date: | 2003-10-24 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Binding Structure of Elastase Inhibitor Scyptolin A
Chem.Biol., 10, 2003
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1ORF
 | | The Oligomeric Structure of Human Granzyme A Reveals the Molecular Determinants of Substrate Specificity | | Descriptor: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Granzyme A, SULFATE ION | | Authors: | Bell, J.K, Goetz, D.H, Mahrus, S, Harris, J.L, Fletterick, R.J, Craik, C.S. | | Deposit date: | 2003-03-12 | | Release date: | 2003-07-01 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The oligomeric structure of human granzyme A is a determinant of its extended substrate specificity.
Nat.Struct.Biol., 10, 2003
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1OOK
 | | Crystal Structure of the Complex of Platelet Receptor GPIb-alpha and Human alpha-Thrombin | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Human Alpha Thrombin, ... | | Authors: | Varughese, K.I, Celikel, R, Ruggeri, Z.M. | | Deposit date: | 2003-03-03 | | Release date: | 2003-07-22 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Modulation of alpha-thrombin function by distinct interactions with platelet
glycoprotein Ibalpha
Science, 301, 2003
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1P0S
 | | Crystal Structure of Blood Coagulation Factor Xa in Complex with Ecotin M84R | | Descriptor: | Coagulation factor X precursor, Ecotin precursor, MAGNESIUM ION, ... | | Authors: | Wang, S.X, Hur, E, Sousa, C.A, Brinen, L, Slivka, E.J, Fletterick, R.J. | | Deposit date: | 2003-04-10 | | Release date: | 2003-08-26 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The Extended Interactions and Gla Domain of Blood Coagulation Factor Xa
Biochemistry, 42, 2003
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1P11
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1P12
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1P09
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5AJM
 | | H5 (VN1194) Asn186Lys Mutant Haemagglutinin in Complex with Avian Receptor Analogue 3'SLN | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ... | | Authors: | Xiong, X, Xiao, H, Martin, S.R, Coombs, P.J, Liu, J, Collins, P.J, Vachieri, S.G, Walker, P.A, Lin, Y.P, McCauley, J.W, Gamblin, S.J, Skehel, J.J. | | Deposit date: | 2015-02-25 | | Release date: | 2015-03-25 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Enhanced Human Receptor Binding by H5 Haemagglutinins.
Virology, 456, 2014
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5A3I
 | | Crystal Structure of a Complex formed between FLD194 Fab and Transmissible Mutant H5 Haemagglutinin | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTI-HAEMAGGLUTININ HA1 FAB HEAVY CHAIN, ... | | Authors: | Xiong, X, Corti, D, Liu, J, Pinna, D, Foglierini, M, Calder, L.J, Martin, S.R, Lin, Y.P, Walker, P.A, Collins, P.J, Monne, I, Suguitan Jr, A.L, Santos, C, Temperton, N.J, Subbarao, K, Lanzavecchia, A, Gamblin, S.J, Skehel, J.J. | | Deposit date: | 2015-06-01 | | Release date: | 2015-07-22 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | Structures of Complexes Formed by H5 Influenza Hemagglutinin with a Potent Broadly Neutralizing Human Monoclonal Antibody.
Proc.Natl.Acad.Sci.USA, 112, 2015
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1E0F
 | | Crystal structure of the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor | | Descriptor: | HAEMADIN, THROMBIN | | Authors: | Richardson, J.L, Kroeger, B, Hoefken, W, Pereira, P, Huber, R, Bode, W, Fuentes-Prior, P. | | Deposit date: | 2000-03-27 | | Release date: | 2000-11-03 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal Structure of the Human Alpha-Thrombin-Haemadin Complex: An Exosite II-Binding Inhibitor
Embo J., 19, 2000
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1DIT
 | | COMPLEX OF A DIVALENT INHIBITOR WITH THROMBIN | | Descriptor: | ALPHA-THROMBIN, PEPTIDE INHIBITOR CVS995 | | Authors: | Tulinsky, A, Krishnan, R. | | Deposit date: | 1995-07-20 | | Release date: | 1996-06-10 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Synthesis, structure, and structure-activity relationships of divalent thrombin inhibitors containing an alpha-keto-amide transition-state mimetic.
Protein Sci., 5, 1996
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1GBK
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1GBB
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1GBI
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1GBL
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1GBC
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1GBH
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2AIP
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1LQX
 | | Crystal structure of V45E mutant of cytochrome b5 | | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, cytochrome b5 | | Authors: | Gan, J.-H, Wu, J, Wang, Z.-Q, Wang, Y.-H, Huang, Z.-X, Xia, Z.-X. | | Deposit date: | 2002-05-14 | | Release date: | 2002-09-04 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structures of V45E and V45Y mutants and structure comparison of a variety of cytochrome b5 mutants.
Acta Crystallogr.,Sect.D, 58, 2002
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1LR6
 | | Crystal structure of V45Y mutant of cytochrome b5 | | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, cytochrome b5 | | Authors: | Gan, J.-H, Wu, J, Wang, Z.-Q, Wang, Y.-H, Huang, Z.-X, Xia, Z.-X. | | Deposit date: | 2002-05-15 | | Release date: | 2002-09-04 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structures of V45E and V45Y mutants and structure comparison of a variety of cytochrome b5 mutants.
Acta Crystallogr.,Sect.D, 58, 2002
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5MF5
 | | PA3825-EAL Mg-CdG Structure | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Diguanylate phosphodiesterase, MAGNESIUM ION | | Authors: | Horrell, S, Bellini, D, Strange, R, Wagner, A, Walsh, M. | | Deposit date: | 2016-11-17 | | Release date: | 2016-12-21 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases.
Sci Rep, 7, 2017
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6AOD
 | | FXIa antibody complex | | Descriptor: | COBALT (II) ION, Coagulation factor XI, FXIa Antibody FAB Heavy Chain, ... | | Authors: | Lolicato, M, Minor, D.L. | | Deposit date: | 2017-08-15 | | Release date: | 2018-03-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Basis for Activity and Specificity of an Anticoagulant Anti-FXIa Monoclonal Antibody and a Reversal Agent.
Structure, 26, 2018
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7M1P
 | | Human ABCA4 structure in the unbound state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Retinal-specific phospholipid-transporting ATPase ABCA4, ... | | Authors: | Scortecci, J.F, Van Petegem, F, Molday, R.S. | | Deposit date: | 2021-03-14 | | Release date: | 2021-09-08 | | Last modified: | 2021-10-20 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease.
Nat Commun, 12, 2021
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