5A3I

Crystal Structure of a Complex formed between FLD194 Fab and Transmissible Mutant H5 Haemagglutinin

Summary for 5A3I

• Entry DOI: 10.2210/pdb5a3i/pdb
• Descriptor: HEMAGGLUTININ, ANTI-HAEMAGGLUTININ HA1 FAB HEAVY CHAIN, ANTI-HAEMAGGLUTININ HA1 FAB LIGHT CHAIN, ... (7 entities in total)
• Functional Keywords: viral protein, haemagglutinin, neutralizing antibody, bird flu, h5n1, influenza virus, glycoprotein
• Biological source: INFLUENZA A VIRUS (A/VIETNAM/1203/2004(H5N1)) (INFLUENZA VIRUS); More
• Total number of polymer chains: 8
• Total formula weight: 210512.78

Authors

Xiong, X.,Corti, D.,Liu, J.,Pinna, D.,Foglierini, M.,Calder, L.J.,Martin, S.R.,Lin, Y.P.,Walker, P.A.,Collins, P.J.,Monne, I.,Suguitan Jr, A.L.,Santos, C.,Temperton, N.J.,Subbarao, K.,Lanzavecchia, A.,Gamblin, S.J.,Skehel, J.J. (deposition date: 2015-06-01, release date: 2015-07-22, Last modification date: 2024-01-10)

• Primary citation: Xiong, X.,Corti, D.,Liu, J.,Pinna, D.,Foglierini, M.,Calder, L.J.,Martin, S.R.,Lin, Y.P.,Walker, P.A.,Collins, P.J.,Monne, I.,Suguitan, A.L.J.,Santos, C.,Temperton, N.J.,Subbarao, K.,Lanzavecchia, A.,Gamblin, S.J.,Skehel, J.J.; Structures of Complexes Formed by H5 Influenza Hemagglutinin with a Potent Broadly Neutralizing Human Monoclonal Antibody.; Proc.Natl.Acad.Sci.USA, 112:9430-, 2015; PubMed: 26170284; DOI: 10.1073/PNAS.1510816112

Experimental method

X-RAY DIFFRACTION (2.89 Å)